Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications

The acute stress response in the multi-omic era

(2021) Amalia Floriou-Servou et al.   BIOLOGICAL PSYCHIATRY

State-dependent responses to intracranial brain stimulation in a patient with depression

(2021) Katherine W. Scangos et al.   NATURE MEDICINE

Precision clinical trials: a framework for getting to precision medicine for neurobehavioural disorders

(2021) Eric J. Lenze et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Evidences for Adult Hippocampal Neurogenesis in Humans

(2021) Elena P. Moreno-Jiménez et al.   JOURNAL OF NEUROSCIENCE

Precision medicine for mood disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs

(2021) H. Le-Niculescu et al.   MOLECULAR PSYCHIATRY

Personalising transcranial magnetic stimulation for depression using neuroimaging: A systematic review

(2021) Anish Modak et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

CD47 in the Brain and Neurodegeneration: An Update on the Role in Neuroinflammatory Pathways

(2021) Seyed Mohammad Gheibihayat et al.   MOLECULES

Ventromedial prefrontal cortex/anterior cingulate cortex Glx, glutamate, and GABA levels in medication-free major depressive disorder

(2021) Joshua T. Kantrowitz et al.   Translational Psychiatry

How do serotonergic psychedelics treat depression: The potential role of neuroplasticity

(2021) Hewa Artin et al.   World Journal of Psychiatry

An assessment of the existence of adult neurogenesis in humans and value of its rodent models for neuropsychiatric diseases

(2021) Alvaro Duque et al.   MOLECULAR PSYCHIATRY

Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells

(2021) Daniel Franjic et al.   NEURON

Sub-regional hippocampal volumes in first-episode drug-naïve major depression disorder

(2021) Mu-N Liu et al.   NEUROSCIENCE LETTERS

Impact of neurodegenerative diseases on human adult hippocampal neurogenesis

(2021) J. Terreros-Roncal et al.   SCIENCE

Abnormal resting-state functional connectivity of hippocampal subfields in patients with major depressive disorder

(2020) Zi Yu Hao et al.   BMC Psychiatry

Unraveling human adult hippocampal neurogenesis

(2020) Miguel Flor-García et al.   Nature Protocols

Predictors of Cognitive Improvement Following Treatment for Late-Life Depression

(2020) Prabha Siddarth et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

Aluminum trichloride caused hippocampal neural cells death and subsequent depression-like behavior in rats via the activation of IL-1β/JNK signaling pathway

(2020) Haiyang Zhang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Regulation of Adult Neurogenesis in Mammalian Brain

(2020) Maria Victoria Niklison-Chirou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Smaller left hippocampal subfield CA1 volume is associated with reported childhood physical and/or sexual abuse in major depression: A pilot study

(2020) Minlan Yuan et al.   JOURNAL OF AFFECTIVE DISORDERS

Compromised Hippocampal Neuroplasticity in the Interferon-α and Toll-like Receptor-3 Activation-Induced Mouse Depression Model

(2020) Eduardo H. Sanchez-Mendoza et al.   MOLECULAR NEUROBIOLOGY

Pro-BDNF Knockout Causes Abnormal Motor Behaviours and Early Death in Mice

(2020) Hua Li et al.   NEUROSCIENCE

Combinatorial Pharmacogenomic Algorithm is Predictive of Citalopram and Escitalopram Metabolism in Patients with Major Depressive Disorder

(2020) Richard C. Shelton et al.   PSYCHIATRY RESEARCH

Network-based approach to identify molecular signatures in the brains of depressed suicides

(2020) Duan Zeng et al.   PSYCHIATRY RESEARCH

Ketamine and Serotonergic Psychedelics: Common Mechanisms Underlying the Effects of Rapid-Acting Antidepressants

(2020) Bashkim Kadriu et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Early life stress and development: potential mechanisms for adverse outcomes

(2020) Karen E. Smith et al.   Journal of Neurodevelopmental Disorders

Deep brain stimulation for psychiatric disorders: From focal brain targets to cognitive networks

(2020) Christi R.P. Sullivan et al.   NEUROIMAGE

Resilience Is Associated with Larger Dentate Gyrus while Suicide Decedents with Major Depressive Disorder have Fewer Granule Neurons

(2019) Maura Boldrini et al.   BIOLOGICAL PSYCHIATRY

Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease

(2019) Elena P. Moreno-Jiménez et al.   NATURE MEDICINE

A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis

(2019) Daniel A. Berg et al.   CELL

Parsing the Hippocampus in Depression: Chronic Stress, Hippocampal Volume, and Major Depressive Disorder

(2019) Yvette I. Sheline et al.   BIOLOGICAL PSYCHIATRY

Human Hippocampal Neurogenesis Persists in Aged Adults and Alzheimer’s Disease Patients

(2019) Matthew K. Tobin et al.   Cell Stem Cell

S-Ketamine Reverses Hippocampal Dendritic Spine Deficits in Flinders Sensitive Line Rats Within 1 h of Administration

(2019) Giulia Treccani et al.   MOLECULAR NEUROBIOLOGY

Altered Development of Hippocampus-Dependent Associative Learning following Early-Life Adversity

(2019) Hilary K. Lambert et al.   Developmental Cognitive Neuroscience

Effects of early life adversity and FKBP5 genotype on hippocampal subfields volume in major depression

(2019) Pavol Mikolas et al.   JOURNAL OF AFFECTIVE DISORDERS

Novel Neuroimmunologic Therapeutics in Depression: A Clinical Perspective on What We Know So Far

(2019) Michael Roman et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model

(2019) Rebecca B. Price et al.   MOLECULAR PSYCHIATRY

Evidence for additionally increased apoptosis in the peripheral blood mononuclear cells of major depressive patients with a high risk for suicide

(2018) Meysam Amidfar et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Human Hippocampal Neurogenesis Persists throughout Aging

(2018) Maura Boldrini et al.   Cell Stem Cell

Hippocampal Radial Glial Subtypes and Their Neurogenic Potential in Human Fetuses and Healthy and Alzheimer’s Disease Adults

(2018) Sara Cipriani et al.   CEREBRAL CORTEX

Ventral Hippocampal CA1 and CA3 Differentially Mediate Learned Approach-Avoidance Conflict Processing

(2018) Anett Schumacher et al.   CURRENT BIOLOGY

Mechanisms of ketamine action as an antidepressant

(2018) P Zanos et al.   MOLECULAR PSYCHIATRY

Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

(2018) Shawn F. Sorrells et al.   NATURE

Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single-cell RNA sequencing

(2018) Hannah Hochgerner et al.   NATURE NEUROSCIENCE

Serotonergic psychedelics and personality: A systematic review of contemporary research

(2018) José Carlos Bouso et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Empirical evidence for discrete neurocognitive subgroups in patients with non-psychotic major depressive disorder: clinical implications

(2018) Shenghong Pu et al.   PSYCHOLOGICAL MEDICINE

The Hippocampus in Depression: More than the sum of its parts? Advanced Hippocampal Substructure Segmentation in Depression

(2018) Darren W. Roddy et al.   BIOLOGICAL PSYCHIATRY

Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus

(2018) Christoph Anacker et al.   NATURE

The risk factors for depression in cancer patients undergoing chemotherapy: a systematic review

(2018) Shuangshuang Wen et al.   SUPPORTIVE CARE IN CANCER

Considerations for Assessing the Extent of Hippocampal Neurogenesis in the Adult and Aging Human Brain

(2018) Alexandria N. Tartt et al.   Cell Stem Cell

Glutamatergic neurometabolite levels in major depressive disorder: a systematic review and meta-analysis of proton magnetic resonance spectroscopy studies

(2018) Sho Moriguchi et al.   MOLECULAR PSYCHIATRY

Integration of gene expression and brain-wide connectivity reveals the multiscale organization of mouse hippocampal networks

(2018) Michael S. Bienkowski et al.   NATURE NEUROSCIENCE

Influence of mTOR signaling pathway on ketamine-induced injuries in the hippocampal neurons of rats

(2018) Fei-fei Liu et al.   NEUROLOGICAL RESEARCH

Integral Characterization of Defective BDNF/TrkB Signalling in Neurological and Psychiatric Disorders Leads the Way to New Therapies

(2017) Gonzalo Tejeda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Analysing UK clinicians’ understanding of cognitive symptoms in major depression: A survey of primary care physicians and psychiatrists

(2017) R. Hamish McAllister-Williams et al.   JOURNAL OF AFFECTIVE DISORDERS

Antidepressant effects of ketamine and the roles of AMPA glutamate receptors and other mechanisms beyond NMDA receptor antagonism

(2017) Lily R. Aleksandrova et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Serotonin and neuroplasticity – Links between molecular, functional and structural pathophysiology in depression

(2017) Christoph Kraus et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

From Serotonin to Neuroplasticity: Evolvement of Theories for Major Depressive Disorder

(2017) Bangshan Liu et al.   Frontiers in Cellular Neuroscience

Efficacy and Safety of Selective Serotonin Reuptake Inhibitors, Serotonin-Norepinephrine Reuptake Inhibitors, and Placebo for Common Psychiatric Disorders Among Children and Adolescents

(2017) Cosima Locher et al.   JAMA Psychiatry

Depletion of adult neurogenesis using the chemotherapy drug temozolomide in mice induces behavioural and biological changes relevant to depression

(2017) M Egeland et al.   Translational Psychiatry

Efficacy of antidepressants: bias in randomized clinical trials and related issues

(2017) Sheng-Min Wang et al.   Expert Review of Clinical Pharmacology

Chronic Stress Triggers Expression of Immediate Early Genes and Differentially Affects the Expression of AMPA and NMDA Subunits in Dorsal and Ventral Hippocampus of Rats

(2017) Anibal Pacheco et al.   Frontiers in Molecular Neuroscience

Effects of the Social Environment and Stress on Glucocorticoid Receptor Gene Methylation: A Systematic Review

(2016) Gustavo Turecki et al.   BIOLOGICAL PSYCHIATRY

Ketamine: NMDA Receptors and Beyond

(2016) C. F. Zorumski et al.   JOURNAL OF NEUROSCIENCE

Erratum: State-Dependent Partial Occlusion of Cortical LTP-Like Plasticity in Major Depression

(2016) Marion Kuhn et al.   NEUROPSYCHOPHARMACOLOGY

Cognition as a treatment target in depression

(2016) M. Kaser et al.   PSYCHOLOGICAL MEDICINE

Abnormality in glutamine–glutamate cycle in the cerebrospinal fluid of cognitively intact elderly individuals with major depressive disorder: a 3-year follow-up study

(2016) K Hashimoto et al.   Translational Psychiatry

Dentate gyrus volume and memory performance in major depressive disorder

(2015) Scott Travis et al.   JOURNAL OF AFFECTIVE DISORDERS

Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors

(2015) Alexis S Hill et al.   NEUROPSYCHOPHARMACOLOGY

Norbin ablation results in defective adult hippocampal neurogenesis and depressive-like behavior in mice

(2015) Hong Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression and function of Neuregulin 1 and its signaling system ERBB2/3 in the enteric nervous system

(2015) Martina Barrenschee et al.   Frontiers in Cellular Neuroscience

Adult Neurogenesis: An Evolutionary Perspective

(2015) Gerd Kempermann   Cold Spring Harbor Perspectives in Biology

Consequences of cancer treatments on adult hippocampal neurogenesis: implications for cognitive function and depressive symptoms

(2014) G. Pereira Dias et al.   NEURO-ONCOLOGY

Dynamic study of the hippocampal volume by structural MRI in a rat model of depression

(2014) Yifeng Luo et al.   NEUROLOGICAL SCIENCES

Deep Brain Stimulation of the Human Reward System for Major Depression—Rationale, Outcomes and Outlook

(2014) Thomas E Schlaepfer et al.   NEUROPSYCHOPHARMACOLOGY

Acute hypernatremia dampens stress-induced enhancement of long-term potentiation in the dentate gyrus of rat hippocampus

(2014) Chiung-Chun Huang et al.   PSYCHONEUROENDOCRINOLOGY

Neurogenesis in the embryonic and adult brain: same regulators, different roles

(2014) Noelia Urbán et al.   Frontiers in Cellular Neuroscience

Abnormal Amygdala Resting-State Functional Connectivity in Adolescent Depression

(2014) Kathryn R. Cullen et al.   JAMA Psychiatry

mTOR signaling and its roles in normal and abnormal brain development

(2014) Nobuyuki Takei et al.   Frontiers in Molecular Neuroscience

Relation Between Structural and Functional Connectivity in Major Depressive Disorder

(2013) Bart de Kwaasteniet et al.   BIOLOGICAL PSYCHIATRY

Structural Changes in Hippocampal Subfields in Major Depressive Disorder: A High-Field Magnetic Resonance Imaging Study

(2013) Yushan Huang et al.   BIOLOGICAL PSYCHIATRY

Real-time fMRI brain computer interfaces: Self-regulation of single brain regions to networks

(2013) Sergio Ruiz et al.   BIOLOGICAL PSYCHOLOGY

Dynamics of Hippocampal Neurogenesis in Adult Humans

(2013) Kirsty L. Spalding et al.   CELL

COGNITIVE DEFICITS AND FUNCTIONAL OUTCOMES IN MAJOR DEPRESSIVE DISORDER: DETERMINANTS, SUBSTRATES, AND TREATMENT INTERVENTIONS

(2013) Roger S. McIntyre et al.   DEPRESSION AND ANXIETY

Prediction of antidepressant treatment response from gray matter volume across diagnostic categories

(2013) Philipp G. Sämann et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Distinctive population ofGfap-expressing neural progenitors arising around the dentate notch migrate and form the granule cell layer in the developing hippocampus

(2013) Tatsunori Seki et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Glucocorticoid receptor protein expression in human hippocampus; stability with age

(2013) Qian Wang et al.   NEUROBIOLOGY OF AGING

The Ventral Hippocampus Is the Embryonic Origin for Adult Neural Stem Cells in the Dentate Gyrus

(2013) Guangnan Li et al.   NEURON

AMPARs and Synaptic Plasticity: The Last 25 Years

(2013) Richard L. Huganir et al.   NEURON

Neuroplasticity in Depressed Individuals Compared with Healthy Controls

(2013) Michael J Player et al.   NEUROPSYCHOPHARMACOLOGY

Hippocampal Granule Neuron Number and Dentate Gyrus Volume in Antidepressant-Treated and Untreated Major Depression

(2013) Maura Boldrini et al.   NEUROPSYCHOPHARMACOLOGY

Amelioration of Cognitive Control in Depression by Transcranial Direct Current Stimulation

(2012) Larissa Wolkenstein et al.   BIOLOGICAL PSYCHIATRY

Impaired Cognitive Function and Hippocampal Neurogenesis following Cancer Chemotherapy

(2012) L.-A. Christie et al.   CLINICAL CANCER RESEARCH

Adult-born hippocampal neurons promote cognitive flexibility in mice

(2012) Nesha S. Burghardt et al.   HIPPOCAMPUS

Altered expression of synapse and glutamate related genes in post-mortem hippocampus of depressed subjects

(2012) Vanja Duric et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Disrupted resting-state functional connectivity of the hippocampus in medication-naïve patients with major depressive disorder

(2012) Xiaohua Cao et al.   JOURNAL OF AFFECTIVE DISORDERS

Antidepressant effects of sertraline associated with volume increases in dorsolateral prefrontal cortex

(2012) Ryan Smith et al.   JOURNAL OF AFFECTIVE DISORDERS

BDNF Promotes Differentiation and Maturation of Adult-born Neurons through GABAergic Transmission

(2012) E. G. Waterhouse et al.   JOURNAL OF NEUROSCIENCE

Monoamine Theories of Depression: Historical Impact on Biomedical Research

(2012) Shai Mulinari   Journal of the History of the Neurosciences

Epigenetic regulation of BDNF expression according to antidepressant response

(2012) J P Lopez et al.   MOLECULAR PSYCHIATRY

State-dependent changes in hippocampal grey matter in depression

(2012) D Arnone et al.   MOLECULAR PSYCHIATRY

New neurons for 'survival of the fittest'

(2012) Gerd Kempermann   NATURE REVIEWS NEUROSCIENCE

Repeated Stress Causes Cognitive Impairment by Suppressing Glutamate Receptor Expression and Function in Prefrontal Cortex

(2012) Eunice Y. Yuen et al.   NEURON

Blockade of Astrocytic Glutamate Uptake in the Prefrontal Cortex Induces Anhedonia

(2012) Catherine S John et al.   NEUROPSYCHOPHARMACOLOGY

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

Early life adversity is associated with brain changes in subjects at family risk for depression

(2012) Angela Carballedo et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Synapses and Memory Storage

(2012) M. Mayford et al.   Cold Spring Harbor Perspectives in Biology

Limbic Scars: Long-Term Consequences of Childhood Maltreatment Revealed by Functional and Structural Magnetic Resonance Imaging

(2011) Udo Dannlowski et al.   BIOLOGICAL PSYCHIATRY

Cell atrophy and loss in depression: reversal by antidepressant treatment

(2011) Mounira Banasr et al.   CURRENT OPINION IN CELL BIOLOGY

Neural mechanisms of the cognitive model of depression

(2011) Seth G. Disner et al.   NATURE REVIEWS NEUROSCIENCE

Pattern Separation: A Common Function for New Neurons in Hippocampus and Olfactory Bulb

(2011) Amar Sahay et al.   NEURON

The neurogenesis hypothesis of affective and anxiety disorders: Are we mistaking the scaffolding for the building?

(2011) David Petrik et al.   NEUROPHARMACOLOGY

Interleukin-1β: A New Regulator of the Kynurenine Pathway Affecting Human Hippocampal Neurogenesis

(2011) Patricia A Zunszain et al.   NEUROPSYCHOPHARMACOLOGY

The Cell Biology of Synaptic Plasticity

(2011) V. M. Ho et al.   SCIENCE

Neuronal Calcium Homeostasis and Dysregulation

(2010) Marc Gleichmann et al.   ANTIOXIDANTS & REDOX SIGNALING

Effect of brain-derived neurotrophic factor haploinsufficiency on stress-induced remodeling of hippocampal neurons

(2010) A.M. Magariños et al.   HIPPOCAMPUS

Altered expression of glutamate signaling, growth factor and glia genes in the locus coeruleus of patients with major depression

(2010) R Bernard et al.   MOLECULAR PSYCHIATRY

Presence of individual (residual) symptoms during depressive episodes and periods of remission: a 3-year prospective study

(2010) H. J. Conradi et al.   PSYCHOLOGICAL MEDICINE

The change in plasma GABA, glutamine and glutamate levels in fluoxetine- or S-citalopram-treated female patients with major depression

(2009) Esra Küçükibrahimoğlu et al.   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Adult hippocampal neurogenesis is involved in anxiety-related behaviors

(2009) J-M Revest et al.   MOLECULAR PSYCHIATRY

Network perspectives on the mechanisms of deep brain stimulation

(2009) Cameron C. McIntyre et al.   NEUROBIOLOGY OF DISEASE

Neurogenesis-Dependent and -Independent Effects of Fluoxetine in an Animal Model of Anxiety/Depression

(2009) Denis J. David et al.   NEURON

Translational Control of Long-Lasting Synaptic Plasticity and Memory

(2009) Mauro Costa-Mattioli et al.   NEURON

Antidepressants increase neural progenitor cells in the human hippocampus

(2009) Maura Boldrini et al.   NEUROPSYCHOPHARMACOLOGY

Neurocircuitry of Mood Disorders

(2009) Joseph L Price et al.   NEUROPSYCHOPHARMACOLOGY

Adult-Generated Hippocampal Neurons Allow the Flexible Use of Spatially Precise Learning Strategies

(2009) Alexander Garthe et al.   PLoS One

Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis

(2009) M Bryant Howren et al.   PSYCHOSOMATIC MEDICINE

A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation

(2009) C. D. Clelland et al.   SCIENCE

Balancing Structure and Function at Hippocampal Dendritic Spines

(2008) Jennifer N Bourne et al.   Annual Review of Neuroscience

Neural Substrates of Increased Memory Sensitivity for Negative Stimuli in Major Depression

(2008) J. Paul Hamilton et al.   BIOLOGICAL PSYCHIATRY

Differential regulation of central BDNF protein levels by antidepressant and non-antidepressant drug treatments

(2008) Darrick T. Balu et al.   BRAIN RESEARCH

Antidepressant treatment normalizes hypoactivity in dorsolateral prefrontal cortex during emotional interference processing in major depression

(2008) Christina L. Fales et al.   JOURNAL OF AFFECTIVE DISORDERS

Protein Synthesis and Neurotrophin-Dependent Structural Plasticity of Single Dendritic Spines

(2008) J.-i. Tanaka et al.   SCIENCE

Altered Emotional Interference Processing in Affective and Cognitive-Control Brain Circuitry in Major Depression

(2007) Christina L. Fales et al.   BIOLOGICAL PSYCHIATRY

Molecular and cellular mechanisms of memory allocation in neuronetworks

(2007) Jaejoon Won et al.   NEUROBIOLOGY OF LEARNING AND MEMORY