Precision medicine for mood disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

(2019) David M. Howard et al.   NATURE NEUROSCIENCE

Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs

(2019) A. B. Niculescu et al.   MOLECULAR PSYCHIATRY

Towards precision medicine for stress disorders: diagnostic biomarkers and targeted drugs

(2019) H. Le-Niculescu et al.   MOLECULAR PSYCHIATRY

Genome-wide association study identifies 30 loci associated with bipolar disorder

(2019) Eli A. Stahl et al.   NATURE GENETICS

Convergence of recent GWAS data for suicidality with previous blood biomarkers: independent reproducibility using independent methodologies in independent cohorts

(2019) A. B. Niculescu et al.   MOLECULAR PSYCHIATRY

Time Course of Changes in Peripheral Blood Gene Expression During Medication Treatment for Major Depressive Disorder

(2019) Ian A. Cook et al.   Frontiers in Genetics

Cell-Type-Specific Methylome-wide Association Studies Implicate Neurotrophin and Innate Immune Signaling in Major Depressive Disorder

(2019) Robin F. Chan et al.   BIOLOGICAL PSYCHIATRY

The genetics of the mood disorder spectrum: genome-wide association analyses of over 185,000 cases and 439,000 controls

(2019) Jonathan R.I. Coleman et al.   BIOLOGICAL PSYCHIATRY

Blood biomarkers for memory: toward early detection of risk for Alzheimer disease, pharmacogenomics, and repurposed drugs

(2019) A. B. Niculescu et al.   MOLECULAR PSYCHIATRY

Precision medicine for suicidality: from universality to subtypes and personalization

(2017) A B Niculescu et al.   MOLECULAR PSYCHIATRY

Sex-specific transcriptional signatures in human depression

(2017) Benoit Labonté et al.   NATURE MEDICINE

Whole-Genome Sequencing of a Healthy Aging Cohort

(2016) Galina A. Erikson et al.   CELL

Mood, stress and longevity: convergence on ANK3

(2016) S Rangaraju et al.   MOLECULAR PSYCHIATRY

Towards understanding and predicting suicidality in women: biomarkers and clinical risk assessment

(2016) D F Levey et al.   MOLECULAR PSYCHIATRY

Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility

(2016) Rosemary C. Bagot et al.   NEURON

Dissecting Suicidality Using a Combined Genomic and Clinical Approach

(2016) Alexander B Niculescu et al.   NEUROPSYCHOPHARMACOLOGY

Effects of Long-Term Environmental Enrichment on Anxiety, Memory, Hippocampal Plasticity and Overall Brain Gene Expression in C57BL6 Mice

(2016) Melanie Hüttenrauch et al.   Frontiers in Molecular Neuroscience

Understanding and predicting suicidality using a combined genomic and clinical risk assessment approach

(2015) A B Niculescu et al.   MOLECULAR PSYCHIATRY

The transcriptional landscape of age in human peripheral blood

(2015) Marjolein J. Peters et al.   Nature Communications

Blood biomarkers of depression track clinical changes during cognitive-behavioral therapy

(2014) Szabolcs Kéri et al.   JOURNAL OF AFFECTIVE DISORDERS

Discovery and validation of blood biomarkers for suicidality

(2013) H Le-Niculescu et al.   MOLECULAR PSYCHIATRY

Personal Omics Profiling Reveals Dynamic Molecular and Medical Phenotypes

(2012) Rui Chen et al.   CELL

Cellular Circadian Clocks in Mood Disorders

(2012) Michael J. McCarthy et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Increased peripheral blood expression of electron transport chain genes in bipolar depression

(2010) Robert D Beech et al.   BIPOLAR DISORDERS

Clinical variations modulate patterns of gene expression and define blood biomarkers in major depression

(2010) Raoul Belzeaux et al.   JOURNAL OF PSYCHIATRIC RESEARCH

A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

(2009) Eric E. Zhang et al.   CELL

Identification of blood biomarkers for psychosis using convergent functional genomics

(2009) S M Kurian et al.   MOLECULAR PSYCHIATRY

Phenomic, Convergent Functional Genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism

(2008) H. Le-Niculescu et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Identifying blood biomarkers for mood disorders using convergent functional genomics

(2008) H Le-Niculescu et al.   MOLECULAR PSYCHIATRY