The role of autophagy in death of cardiomyocytes

The roles of the inhibitory autophagy regulator Rubicon in the heart: A new therapeutic target to prevent cardiac cell death

(2021) Jihoon Nah et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Autophagic Cell Death During Development – Ancient and Mysterious

(2021) Lawrence M. Schwartz   Frontiers in Cell and Developmental Biology

atg7-Based Autophagy Activation Reverses Doxorubicin-Induced Cardiotoxicity

(2021) Yong Wang et al.   CIRCULATION RESEARCH

Alleviation of a polyglucosan storage disorder by enhancement of autophagic glycogen catabolism

(2021) Or Kakhlon et al.   EMBO Molecular Medicine

Alternative Mitophagy Protects the Heart Against Obesity-Associated Cardiomyopathy

(2021) Mingming Tong et al.   CIRCULATION RESEARCH

Exaggerated mitophagy: a weapon of striatal destruction in the brain?

(2020) Srinivasa Subramaniam   BIOCHEMICAL SOCIETY TRANSACTIONS

Activation of autophagy inhibits NLRP3 inflammasome activation and attenuates myocardial ischemia‐reperfusion injury in diabetic rats

(2020) Dengwen Zhang et al.   Journal of Diabetes Investigation

Autophagosome biogenesis: From membrane growth to closure

(2020) Thomas J. Melia et al.   JOURNAL OF CELL BIOLOGY

Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury

(2020) Jihoon Nah et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy as a decisive process for cell death

(2020) Seonghee Jung et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Autophagy in Human Diseases

(2020) Noboru Mizushima et al.   NEW ENGLAND JOURNAL OF MEDICINE

Decoding three distinct states of the Syntaxin17 SNARE motif in mediating autophagosome–lysosome fusion

(2020) Ying Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired autophagy: The collateral damage of lysosomal storage disorders

(2020) Rachel Myerowitz et al.   EBioMedicine

YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases

(2020) Shohei Ikeda et al.   JOURNAL OF CLINICAL INVESTIGATION

Doxorubicin-induced cardiomyocyte death is mediated by unchecked mitochondrial fission and mitophagy

(2019) Michael P. Catanzaro et al.   FASEB JOURNAL

Loss of Rubicon ameliorates doxorubicin-induced cardiotoxicity through enhancement of mitochondrial quality

(2019) Xiaoyun Liu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Impaired NF-κB signalling underlies cyclophilin D-mediated mitochondrial permeability transition pore opening in doxorubicin cardiomyopathy

(2019) Rimpy Dhingra et al.   CARDIOVASCULAR RESEARCH

3,4‐Dimethoxychalcone induces autophagy through activation of the transcription factors TFE 3 and TFEB

(2019) Guo Chen et al.   EMBO Molecular Medicine

The Role of Autophagy in the Heart

(2018) Sebastiano Sciarretta et al.   Annual Review of Physiology

Diabetic Cardiomyopathy

(2018) Guanghong Jia et al.   CIRCULATION RESEARCH

Trehalose-Induced Activation of Autophagy Improves Cardiac Remodeling After Myocardial Infarction

(2018) Sebastiano Sciarretta et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Therapeutic Benefit of Autophagy Modulation in Pompe Disease

(2018) Jeong-A Lim et al.   MOLECULAR THERAPY

Autophagy-dependent cell death

(2018) Donna Denton et al.   CELL DEATH AND DIFFERENTIATION

LAMP-2B regulates human cardiomyocyte function by mediating autophagosome–lysosome fusion

(2018) Congwu Chi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ellagic acid antagonizes Bnip3-mediated mitochondrial injury and necrotic cell death of cardiac myocytes

(2017) Abhinav Dhingra et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy and mitophagy in the context of doxorubicin-induced cardiotoxicity

(2017) Navid Koleini et al.   Oncotarget

Doxorubicin Blocks Cardiomyocyte Autophagic Flux by Inhibiting Lysosome AcidificationCLINICAL PERSPECTIVE

(2016) Dan L. Li et al.   CIRCULATION

Regulation of autophagy by Beclin 1 in the heart

(2016) Yasuhiro Maejima et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts

(2015) Moshi Song et al.   Cell Metabolism

Autosis occurs in the liver of patients with severe anorexia nervosa

(2015) Marouane Kheloufi et al.   HEPATOLOGY

Parkin‐independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain

(2014) Yusuke Kageyama et al.   EMBO JOURNAL

Historical landmarks of autophagy research

(2013) Yoshinori Ohsumi   CELL RESEARCH

p53 Mediates Autophagy and Cell Death by a Mechanism Contingent On Bnip3

(2013) Erika Yan Wang et al.   HYPERTENSION

Diminished Autophagy Limits Cardiac Injury in Mouse Models of Type 1 Diabetes

(2013) Xianmin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a candidate therapeutic autophagy-inducing peptide

(2013) Sanae Shoji-Kawata et al.   NATURE

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

(2013) Yasuhiro Maejima et al.   NATURE MEDICINE

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

(2013) Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death

(2012) Xiucui Ma et al.   Autophagy

Identification of the molecular basis of doxorubicin-induced cardiotoxicity

(2012) Sui Zhang et al.   NATURE MEDICINE

Autophagic cell death: Loch Ness monster or endangered species?

(2011) Han-Ming Shen et al.   Autophagy

Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during lateDrosophila melanogasteroogenesis

(2010) Ioannis P. Nezis et al.   JOURNAL OF CELL BIOLOGY

Is Autophagy in Response to Ischemia and Reperfusion Protective or Detrimental for the Heart?

(2010) Sebastiano Sciarretta et al.   PEDIATRIC CARDIOLOGY

Autophagy, Not Apoptosis, Is Essential for Midgut Cell Death in Drosophila

(2009) Donna Denton et al.   CURRENT BIOLOGY

Transcription Factor GATA4 Inhibits Doxorubicin-induced Autophagy and Cardiomyocyte Death

(2009) Satoru Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recycle or die: The role of autophagy in cardioprotection

(2008) Åsa B. Gustafsson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY