Impaired NF-κB signalling underlies cyclophilin D-mediated mitochondrial permeability transition pore opening in doxorubicin cardiomyopathy

Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy

(2017) Tania Zaglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

F 1 F 0 ATP Synthase–Cyclophilin D Interaction Contributes to Diabetes-Induced Synaptic Dysfunction and Cognitive Decline

(2016) Shijun Yan et al.   DIABETES

Cyclosporine before PCI in Acute Myocardial Infarction

(2016)   NEW ENGLAND JOURNAL OF MEDICINE

PDK2-mediated alternative splicing switches Bnip3 from cell death to cell survival

(2015) Hongying Gang et al.   JOURNAL OF CELL BIOLOGY

The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology

(2015) Paolo Bernardi et al.   PHYSIOLOGICAL REVIEWS

Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation

(2014) Yoshihiko Ichikawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Bnip3 mediates doxorubicin-induced cardiac myocyte necrosis and mortality through changes in mitochondrial signaling

(2014) Rimpy Dhingra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic regulation of canonical TNFα pathway by HDAC1 determines survival of cardiac myocytes

(2013) Hongying Gang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Bidirectional Regulation of Nuclear Factor-κB and Mammalian Target of Rapamycin Signaling Functionally Links Bnip3 Gene Repression and Cell Survival of Ventricular Myocytes

(2013) Rimpy Dhingra et al.   Circulation-Heart Failure

Treatment-related cardiotoxicity in survivors of childhood cancer

(2013) Steven E. Lipshultz et al.   Nature Reviews Clinical Oncology

Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies

(2012) Yanti Octavia et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A Novel Hypoxia-Inducible Spliced Variant of Mitochondrial Death Gene Bnip3 Promotes Survival of Ventricular Myocytes

(2011) Hongying Gang et al.   CIRCULATION RESEARCH

Multiple Facets of NF-κB in the Heart

(2011) Joseph W. Gordon et al.   CIRCULATION RESEARCH

Cysteine 203 of Cyclophilin D Is Critical for Cyclophilin D Activation of the Mitochondrial Permeability Transition Pore

(2011) Tiffany T. Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Epigenetic Regulation of E2F-1-Dependent Bnip3 Transcription and Cell Death by Nuclear Factor-κB and Histone Deacetylase-1

(2011) Hongying Gang et al.   PEDIATRIC CARDIOLOGY

Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

(2010) John W. Elrod et al.   JOURNAL OF CLINICAL INVESTIGATION

Akt-dependent regulation of NF- B is controlled by mTOR and Raptor in association with IKK

(2008) H. C. Dan et al.   GENES & DEVELOPMENT

The Cell Cycle Factor E2F-1 Activates Bnip3 and the Intrinsic Death Pathway in Ventricular Myocytes

(2007) Natalia Yurkova et al.   CIRCULATION RESEARCH