Alternative Mitophagy Protects the Heart Against Obesity-Associated Cardiomyopathy

Nampt Potentiates Antioxidant Defense in Diabetic Cardiomyopathy

(2021) Shin-ichi Oka et al.   CIRCULATION RESEARCH

Increased Drp1 Acetylation by Lipid Overload Induces Cardiomyocyte Death and Heart Dysfunction

(2020) Qingxun Hu et al.   CIRCULATION RESEARCH

Increasing Fatty Acid Oxidation Prevents High Fat Diet Induced Cardiomyopathy through Regulating Parkin Mediated Mitophagy

(2020) Dan Shao et al.   CIRCULATION

Molecular Mechanisms And Clinical Implications Of Multiple Forms Of Mitophagy In The Heart

(2020) Toshiro Saito et al.   CARDIOVASCULAR RESEARCH

Hippo Deficiency Leads to Cardiac Dysfunction Accompanied by Cardiomyocyte Dedifferentiation During Pressure Overload

(2019) Shohei Ikeda et al.   CIRCULATION RESEARCH

The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation

(2019) Haixia Xu et al.   Molecular Metabolism

Cardiomyopathy in obesity, insulin resistance or diabetes

(2019) Michinari Nakamura et al.   JOURNAL OF PHYSIOLOGY-LONDON

Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy

(2019) Mingming Tong et al.   CIRCULATION RESEARCH

Glycogen Synthase Kinase-3α Promotes Fatty Acid Uptake and Lipotoxic Cardiomyopathy

(2019) Michinari Nakamura et al.   Cell Metabolism

BNIP3L/NIX and FUNDC1-mediated mitophagy is required for mitochondrial network remodeling during cardiac progenitor cell differentiation

(2019) Mark A. Lampert et al.   Autophagy

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Trehalose-Induced Activation of Autophagy Improves Cardiac Remodeling After Myocardial Infarction

(2018) Sebastiano Sciarretta et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Evolving Concepts of Mitochondrial Dynamics

(2018) Gerald W. Dorn   Annual Review of Physiology

An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

(2018) Toshiro Saito et al.   JOURNAL OF CLINICAL INVESTIGATION

A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance

(2017) Babette C. Hammerling et al.   Nature Communications

Altered gene expression and repressed markers of autophagy in skeletal muscle of insulin resistant patients with type 2 diabetes

(2017) Andreas Buch Møller et al.   Scientific Reports

Circulating miR-19b and miR-181b are potential biomarkers for diabetic cardiomyopathy

(2017) Camila Uribe Copier et al.   Scientific Reports

TFEB and TFE3: Linking Lysosomes to Cellular Adaptation to Stress

(2016) Nina Raben et al.   Annual Review of Cell and Developmental Biology

Glucolipotoxicity diminishes cardiomyocyte TFEB and inhibits lysosomal autophagy during obesity and diabetes

(2016) Purvi C. Trivedi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Drp1-Dependent Mitochondrial Autophagy Plays a Protective Role Against Pressure Overload–Induced Mitochondrial Dysfunction and Heart FailureCLINICAL PERSPECTIVE

(2016) Akihiro Shirakabe et al.   CIRCULATION

A Simplified, Langendorff-Free Method for Concomitant Isolation of Viable Cardiac Myocytes and Nonmyocytes From the Adult Mouse HeartNovelty and Significance

(2016) Matthew Ackers-Johnson et al.   CIRCULATION RESEARCH

TFEB and TFE3 are novel components of the integrated stress response

(2016) J. A. Martina et al.   EMBO JOURNAL

Evaluating mitochondrial autophagy in the mouse heart

(2016) Akihiro Shirakabe et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Mitochondrial Cristae: Where Beauty Meets Functionality

(2016) Sara Cogliati et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mitophagy is primarily due to alternative autophagy and requires the MAPK1 and MAPK14 signaling pathways

(2015) Yuko Hirota et al.   Autophagy

MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5

(2015) Catherine L. Nezich et al.   JOURNAL OF CELL BIOLOGY

Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice

(2015) G. Gong et al.   SCIENCE

A method to measure cardiac autophagic flux in vivo

(2014) Eri Iwai-Kanai et al.   Autophagy

Molecular mechanisms of diabetic cardiomyopathy

(2014) Heiko Bugger et al.   DIABETOLOGIA

Ulk1-mediated Atg5-independent macroautophagy mediates elimination of mitochondria from embryonic reticulocytes

(2014) Shinya Honda et al.   Nature Communications

Mitochondrial fatty acid oxidation alterations in heart failure, ischaemic heart disease and diabetic cardiomyopathy

(2013) N Fillmore et al.   BRITISH JOURNAL OF PHARMACOLOGY

Diminished Autophagy Limits Cardiac Injury in Mouse Models of Type 1 Diabetes

(2013) Xianmin Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mice Long-Term High-Fat Diet Feeding Recapitulates Human Cardiovascular Alterations: An Animal Model to Study the Early Phases of Diabetic Cardiomyopathy

(2013) Sebastián D. Calligaris et al.   PLoS One

Suppression of autophagy is protective in high glucose-induced cardiomyocyte injury

(2012) Satoru Kobayashi et al.   Autophagy

Rheb is a Critical Regulator of Autophagy During Myocardial Ischemia

(2012) Sebastiano Sciarretta et al.   CIRCULATION

PPARα-Sirt1 Complex Mediates Cardiac Hypertrophy and Failure through Suppression of the ERR Transcriptional Pathway

(2011) Shinichi Oka et al.   Cell Metabolism

A Sensitive and Quantitative Technique for Detecting Autophagic Events Based on Lysosomal Delivery

(2011) Hiroyuki Katayama et al.   CHEMISTRY & BIOLOGY

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

Measurement of cardiac function using pressure–volume conductance catheter technique in mice and rats

(2008) Pál Pacher et al.   Nature Protocols