Research progress of endothelial‐mesenchymal transition in diabetic kidney disease

circRNA_010383 Acts as a Sponge for miR-135a, and Its Downregulated Expression Contributes to Renal Fibrosis in Diabetic Nephropathy

(2021) Fenfen Peng et al.   DIABETES

Qishen Yiqi Dripping Pill Protects Against Diabetic Nephropathy by Inhibiting the Wnt/β-Catenin and Transforming Growth Factor-β/Smad Signaling Pathways in Rats

(2021) Qian Zhang et al.   Frontiers in Physiology

Sox9 and Rbpj differentially regulate endothelial to mesenchymal transition and wound scarring in murine endovascular progenitors

(2021) Jilai Zhao et al.   Nature Communications

Loss of endothelial glucocorticoid receptor accelerates diabetic nephropathy

(2021) Swayam Prakash Srivastava et al.   Nature Communications

Endothelial SIRT3 regulates myofibroblast metabolic shifts in diabetic kidneys

(2021) Swayam Prakash Srivastava et al.   iScience

MiR-126-3p Is Dynamically Regulated in Endothelial-to-Mesenchymal Transition during Fibrosis

(2021) Nina P. Jordan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy

(2021) Lihong Lu et al.   MOLECULAR MEDICINE

Tripterygium glycoside suppresses epithelial‑to‑mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

(2021) Mei Tao et al.   Molecular Medicine Reports

Melatonin Treatment Improves Renal Fibrosis via miR-4516/SIAH3/PINK1 Axis

(2021) Yeo Min Yoon et al.   Cells

FGF9/FGFR1 promotes cell proliferation, epithelial-mesenchymal transition, M2 macrophage infiltration and liver metastasis of lung cancer

(2021) Ming-Min Chang et al.   Translational Oncology

AZD4547 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting Inflammation: The Role of FGFR1 in Renal Tubular Epithelial Cells

(2020) Xuemei Chen et al.   Drug Design Development and Therapy

Inhibition of Angiotensin-Converting Enzyme Ameliorates Renal Fibrosis by Mitigating DPP-4 Level and Restoring Antifibrotic MicroRNAs

(2020) Swayam Prakash Srivastava et al.   Genes

Sirt3 modulates fatty acid oxidation and attenuates cisplatin‐induced AKI in mice

(2020) Ming Li et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The MicroRNA MiR-29c Alleviates Renal Fibrosis via TPM1-Mediated Suppression of the Wnt/β-Catenin Pathway

(2020) Huiya Huang et al.   Frontiers in Physiology

MicroRNA-27a targets Sfrp1 to induce renal fibrosis in diabetic nephropathy by activating Wnt/β-Catenin signalling

(2020) MingJun Shi et al.   BIOSCIENCE REPORTS

Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis

(2020) Sara Lovisa et al.   Science Signaling

Effects of ZnT8 on epithelial-to-mesenchymal transition and tubulointerstitial fibrosis in diabetic kidney disease

(2020) Xiuli Zhang et al.   Cell Death & Disease

Endothelial FGFR1 (Fibroblast Growth Factor Receptor 1) Deficiency Contributes Differential Fibrogenic Effects in Kidney and Heart of Diabetic Mice

(2020) Jinpeng Li et al.   HYPERTENSION

Knockdown of LncRNA-H19 Ameliorates Kidney Fibrosis in Diabetic Mice by Suppressing miR-29a-Mediated EndMT

(2020) Sen Shi et al.   Frontiers in Pharmacology

Myeloid differentiation protein 2 mediates angiotensin II-induced inflammation and mesenchymal transition in vascular endothelium

(2020) Jinfu Qian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

China Kidney Disease Network (CK-NET) 2015 Annual Data Report

(2019) Luxia Zhang et al.   Kidney International Supplements

C-reactive protein exacerbates epithelial-mesenchymal transition through Wnt/β-catenin and ERK signaling in streptozocin-induced diabetic nephropathy

(2019) Lin Zhang et al.   FASEB JOURNAL

Challenges in the Pathophysiology, Diagnosis and Management of Intestinal Fibrosis in Inflammatory Bowel Disease

(2019) Geert D’Haens et al.   GASTROENTEROLOGY

SIRT6-mediated transcriptional suppression of MALAT1 is a key mechanism for endothelial to mesenchymal transition

(2019) Wei Qin et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Inhibition of prostaglandin E2 receptor 4 by lnc000908 to promote the endothelial‐mesenchymal transition participation in cardiac remodelling

(2019) Xingxing Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Group 2 Innate Lymphoid Cells Participate in Renal Fibrosis in Diabetic Kidney Disease Partly via TGF-β1 Signal Pathway

(2019) Cuiping Liu et al.   Journal of Diabetes Research

Liraglutide Inhibits Endothelial-to-Mesenchymal Transition and Attenuates Neointima Formation after Endovascular Injury in Streptozotocin-Induced Diabetic Mice

(2019) Tzu-Hsien Tsai et al.   Cells

Emerging role of miRNAs in renal fibrosis

(2019) Youling Fan et al.   RNA Biology

microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney

(2019) Swayam Prakash Srivastava et al.   Frontiers in Pharmacology

Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis

(2019) Ki Wung Chung et al.   Cell Metabolism

Mechanisms of Renal Fibrosis

(2018) Benjamin D. Humphreys   Annual Review of Physiology

Suppression of Endothelial-to-Mesenchymal Transition by SIRT (Sirtuin) 3 Alleviated the Development of Hypertensive Renal InjuryNovelty and Significance

(2018) Jing-rong Lin et al.   HYPERTENSION

LincRNA 1700020I14Rik alleviates cell proliferation and fibrosis in diabetic nephropathy via miR-34a-5p/Sirt1/HIF-1α signaling

(2018) Ailing Li et al.   Cell Death & Disease

The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2

(2018) Philipp Neumann et al.   Nature Communications

Hedgehog Interacting Protein Promotes Fibrosis and Apoptosis in Glomerular Endothelial Cells in Murine Diabetes

(2018) Xin-Ping Zhao et al.   Scientific Reports

Endothelial to Mesenchymal Transition Represents a Key Link in the Interaction between Inflammation and Endothelial Dysfunction

(2018) Jin Gu Cho et al.   Frontiers in Immunology

Inflammation induces endothelial-to-mesenchymal transition and promotes vascular calcification through downregulation of BMPR2

(2018) Gonzalo Sánchez-Duffhues et al.   JOURNAL OF PATHOLOGY

Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury

(2017) Ying-Ying Wang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway

(2017) Jinpeng Li et al.   Cell Death & Disease

How to prevent the microvascular complications of type 2 diabetes beyond glucose control

(2017) Willy Marcos Valencia et al.   BMJ-British Medical Journal

How to prevent the microvascular complications of type 2 diabetes beyond glucose control

(2017) Willy Marcos Valencia et al.   BMJ-British Medical Journal

Lovastatin Alleviates Endothelial-to-Mesenchymal Transition in Glomeruli via Suppression of Oxidative Stress and TGF-β1 Signaling

(2017) Zejun Ma et al.   Frontiers in Pharmacology

Low molecular weight fucoidan ameliorates the inflammation and glomerular filtration function of diabetic nephropathy

(2016) Yingjie Xu et al.   JOURNAL OF APPLIED PHYCOLOGY

TGF-β Signaling from Receptors to Smads

(2016) Akiko Hata et al.   Cold Spring Harbor Perspectives in Biology

Non-Smad Signaling Pathways of the TGF-β Family

(2016) Ying E. Zhang   Cold Spring Harbor Perspectives in Biology

ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy

(2016) Hui Peng et al.   Scientific Reports

Effect of Antifibrotic MicroRNAs Crosstalk on the Action of N-acetyl-seryl-aspartyl-lysyl-proline in Diabetes-related Kidney Fibrosis

(2016) Swayam Prakash Srivastava et al.   Scientific Reports

Secreted HHIP1 interacts with heparan sulfate and regulates Hedgehog ligand localization and function

(2015) Alexander M. Holtz et al.   JOURNAL OF CELL BIOLOGY

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Epithelial-to-Mesenchymal Transition in Diabetic Nephropathy: Fact or Fiction?

(2015) Ivonne Loeffler et al.   Cells

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

Long Noncoding RNAs: Past, Present, and Future

(2013) J. T. Y. Kung et al.   GENETICS

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Origin and function of myofibroblasts in kidney fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Myofibroblasts, regeneration or renal fibrosis--is there a decisive hint?

(2013) J. A. Lindquist et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Role of the Wnt-Frizzled system in cardiac pathophysiology: a rapidly developing, poorly understood area with enormous potential

(2012) Kristin Dawson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Experimental diabetic nephropathy is accelerated in matrix metalloproteinase-2 knockout mice

(2012) Yoshimi Takamiya et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Endothelial glucocorticoid receptor is required for protection against sepsis

(2012) J. E. Goodwin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial-mesenchymal transition in renal fibrosis - evidence for and against

(2011) Maria Fragiadaki et al.   INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY

Tissue inhibitor of metalloproteinase-1 promotes NIH3T3 fibroblast proliferation by activating p-Akt and cell cycle progression

(2011) Yang Lu et al.   MOLECULES AND CELLS

Glucocorticoid enhances hypoxia- and/or transforming growth factor-β-induced plasminogen activator inhibitor-1 production in human proximal renal tubular cells

(2010) Hideki Kimura et al.   Clinical and Experimental Nephrology

The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling

(2009) Ivan Bosanac et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Fibroblasts in Kidney Fibrosis Emerge via Endothelial-to-Mesenchymal Transition

(2008) E. M. Zeisberg et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY