Endothelial FGFR1 (Fibroblast Growth Factor Receptor 1) Deficiency Contributes Differential Fibrogenic Effects in Kidney and Heart of Diabetic Mice

Inhibition of Angiotensin-Converting Enzyme Ameliorates Renal Fibrosis by Mitigating DPP-4 Level and Restoring Antifibrotic MicroRNAs

(2020) Swayam Prakash Srivastava et al.   Genes

Metabolic reprogramming by N‐acetyl‐seryl‐aspartyl‐lysyl‐proline protects against diabetic kidney disease

(2020) Swayam Prakash Srivastava et al.   BRITISH JOURNAL OF PHARMACOLOGY

Altered VEGF Splicing Isoform Balance in Tumor Endothelium Involves Activation of Splicing Factors Srpk1 and Srsf1 by the Wilms’ Tumor Suppressor Wt1

(2019) Kay-Dietrich Wagner et al.   Cells

lncRNA ZEB1-AS1 promotes pulmonary fibrosis through ZEB1-mediated epithelial–mesenchymal transition by competitively binding miR-141-3p

(2019) Weibin Qian et al.   Cell Death & Disease

LRG1 Promotes Diabetic Kidney Disease Progression by Enhancing TGF-β–Induced Angiogenesis

(2019) Quan Hong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

C-reactive protein exacerbates epithelial-mesenchymal transition through Wnt/β-catenin and ERK signaling in streptozocin-induced diabetic nephropathy

(2019) Lin Zhang et al.   FASEB JOURNAL

A KDM6A–KLF10 reinforcing feedback mechanism aggravates diabetic podocyte dysfunction

(2019) Chun‐Liang Lin et al.   EMBO Molecular Medicine

βklotho is essential for the anti‐endothelial mesenchymal transition effects of N ‐acetyl‐seryl‐aspartyl‐lysyl‐proline

(2019) Rongfen Gao et al.   FEBS Open Bio

microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney

(2019) Swayam Prakash Srivastava et al.   Frontiers in Pharmacology

FGFR1 is essential for N -acetyl-seryl-aspartyl-lysyl-proline regulation of mitochondrial dynamics by upregulating microRNA let-7b-5p

(2018) Qiongying Hu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Single-Cell Transcriptome Atlas of the Mouse Glomerulus

(2018) Nikos Karaiskos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

N-acetyl-seryl-aspartyl-lysyl-proline mediates the anti-fibrotic properties of captopril in unilateral ureteric obstructed BALB/C mice

(2018) Gary C.W. Chan et al.   NEPHROLOGY

SIRT3 deficiency leads to induction of abnormal glycolysis in diabetic kidney with fibrosis

(2018) Swayam Prakash Srivastava et al.   Cell Death & Disease

Catechol-O-Methyltransferase Deficiency Leads to Hypersensitivity of the Pressor Response Against Angiotensin IINovelty and Significance

(2017) Norikazu Ueki et al.   HYPERTENSION

TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases

(2017) Evangelia Pardali et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

FGFR1 is critical for the anti-endothelial mesenchymal transition effect of N-acetyl-seryl-aspartyl-lysyl-proline via induction of the MAP4K4 pathway

(2017) Jinpeng Li et al.   Cell Death & Disease

The molecular basis of endothelial cell plasticity

(2017) Elisabetta Dejana et al.   Nature Communications

Visualization of kidney fibrosis in diabetic nephropathy by long diffusion tensor imaging MRI with spin-echo sequence

(2017) Jun-Ya Kaimori et al.   Scientific Reports

Epithelial-mesenchymal transition in tissue repair and fibrosis

(2016) Rivka C. Stone et al.   CELL AND TISSUE RESEARCH

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

(2016) Marco Sciacovelli et al.   NATURE

Interactions between kidney disease and diabetes: dangerous liaisons

(2016) Roberto Pecoits-Filho et al.   Diabetology & Metabolic Syndrome

Oral Administration of N-Acetyl-seryl-aspartyl-lysyl-proline Ameliorates Kidney Disease in Both Type 1 and Type 2 Diabetic Mice via a Therapeutic Regimen

(2016) Kyoko Nitta et al.   Biomed Research International

Effect of Antifibrotic MicroRNAs Crosstalk on the Action of N-acetyl-seryl-aspartyl-lysyl-proline in Diabetes-related Kidney Fibrosis

(2016) Swayam Prakash Srivastava et al.   Scientific Reports

Fibroblast Growth Factor Signaling in the Vasculature

(2015) Xuehui Yang et al.   Current Atherosclerosis Reports

N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP): Potential target molecule in research of heart, kidney and brain

(2015) Jaroslav Hrenak et al.   CURRENT PHARMACEUTICAL DESIGN

Renal Protective Effect ofN-Acetyl-Seryl-Aspartyl-Lysyl-Proline in Dahl Salt-Sensitive RatsNovelty and Significance

(2015) Morel E. Worou et al.   HYPERTENSION

Interactions of DPP-4 and integrin β1 influences endothelial-to-mesenchymal transition

(2015) Sen Shi et al.   KIDNEY INTERNATIONAL

Linagliptin-Mediated DPP-4 Inhibition Ameliorates Kidney Fibrosis in Streptozotocin-Induced Diabetic Mice by Inhibiting Endothelial-to-Mesenchymal Transition in a Therapeutic Regimen

(2014) Keizo Kanasaki et al.   DIABETES

Endothelial cell FGF signaling is required for injury response but not for vascular homeostasis

(2014) Sunday S. Oladipupo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fibroblast growth factor receptor 1 is a key inhibitor of TGF  signaling in the endothelium

(2014) P.-Y. Chen et al.   Science Signaling

N-acetyl-seryl-aspartyl-lysyl-proline Inhibits Diabetes-Associated Kidney Fibrosis and Endothelial-Mesenchymal Transition

(2014) Takako Nagai et al.   Biomed Research International

N-acetyl-seryl-aspartyl-lysyl-proline: a valuable endogenous anti-fibrotic peptide for combating kidney fibrosis in diabetes

(2014) Keizo Kanasaki et al.   Frontiers in Pharmacology

Functional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancers

(2013) Kai Hung Tiong et al.   APOPTOSIS

Thymosin β4 and its degradation product, Ac-SDKP, are novel reparative factors in renal fibrosis

(2013) Yiqin Zuo et al.   KIDNEY INTERNATIONAL

MicroRNAs in Kidney Fibrosis and Diabetic Nephropathy: Roles on EMT and EndMT

(2013) Swayam Prakash Srivastava et al.   Biomed Research International

FGF Regulates TGF-β Signaling and Endothelial-to-Mesenchymal Transition via Control of let-7 miRNA Expression

(2012) Pei-Yu Chen et al.   Cell Reports

FGF-dependent regulation of VEGF receptor 2 expression in mice

(2011) Masahiro Murakami et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphorylation of VE-cadherin controls endothelial phenotypes via p120-catenin coupling and Rac1 activation

(2010) Kunihiko Hatanaka et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

TGF-β-induced epithelial to mesenchymal transition

(2009) Jian Xu et al.   CELL RESEARCH

N-acetyl-seryl-aspartyl-lysyl-proline prevents cardiac remodeling and dysfunction induced by galectin-3, a mammalian adhesion/growth-regulatory lectin

(2008) Yun-He Liu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Frs2 -deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis

(2008) J. Zhang et al.   DEVELOPMENT

The FGF system has a key role in regulating vascular integrity

(2008) Masahiro Murakami et al.   JOURNAL OF CLINICAL INVESTIGATION