The mammalian rhomboid protein RHBDL4 protects against endoplasmic reticulum stress by regulating the morphology and distribution of ER sheets

RHBDD1 silencing inhibited cell growth and invasion of non-small cell lung cancer by mediating ZEB1/PI3K/AKT signaling pathway

(2021) Zheyuan Xu et al.   JOURNAL OF MOLECULAR HISTOLOGY

Endoplasmic reticulum contact sites regulate the dynamics of membraneless organelles

(2020) Jason E. Lee et al.   SCIENCE

Mechanisms, regulation and functions of the unfolded protein response

(2020) Claudio Hetz et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microtubule-dependent and independent roles of spastin in lipid droplet dispersion and biogenesis

(2020) Nimesha Tadepalle et al.   Life Science Alliance

Reconstituting the reticular ER network – mechanistic implications and open questions

(2019) Ning Wang et al.   JOURNAL OF CELL SCIENCE

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4

(2019) Kyojiro N. Ikeda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spastin tethers lipid droplets to peroxisomes and directs fatty acid trafficking through ESCRT-III

(2019) Chi-Lun Chang et al.   JOURNAL OF CELL BIOLOGY

RHBDD1 promotes colorectal cancer metastasis through the Wnt signaling pathway and its downstream target ZEB1

(2018) Mengmeng Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Membrane cholesterol as regulator of human rhomboid protease RHBDL4.

(2018) Sandra Paschkowsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Here, there, and everywhere: The importance of ER membrane contact sites

(2018) Haoxi Wu et al.   SCIENCE

Visualizing Intracellular Organelle and Cytoskeletal Interactions at Nanoscale Resolution on Millisecond Timescales

(2018) Yuting Guo et al.   CELL

Dynamics and functions of lipid droplets

(2018) James A. Olzmann et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Reconstitution of the tubular endoplasmic reticulum network with purified components

(2017) Robert E. Powers et al.   NATURE

Stability properties of neuronal microtubules

(2016) Peter W. Baas et al.   Cytoskeleton

Non-Catalytic Roles of Presenilin Throughout Evolution

(2016) Grant P. Otto et al.   JOURNAL OF ALZHEIMERS DISEASE

Substrates and physiological functions of secretase rhomboid proteases

(2016) Viorica L. Lastun et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Inactive rhomboid proteins: New mechanisms with implications in health and disease

(2016) Marius K. Lemberg et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Structural Basis for the Non-catalytic Functions of Protein Kinases

(2016) Jennifer E. Kung et al.   STRUCTURE

Calcium at the Center of Cell Signaling: Interplay between Endoplasmic Reticulum, Mitochondria, and Lysosomes

(2016) Anna Raffaello et al.   TRENDS IN BIOCHEMICAL SCIENCES

Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFα

(2016) Lina Wunderle et al.   Scientific Reports

Moving targets: Emerging roles for MMPs in cancer progression and metastasis

(2015) Gemma Shay et al.   MATRIX BIOLOGY

Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway

(2015) Wei Song et al.   Nature Communications

ER sheet persistence is coupled to myosin 1c–regulated dynamic actin filament arrays

(2014) Merja Joensuu et al.   MOLECULAR BIOLOGY OF THE CELL

E-CRISP: fast CRISPR target site identification

(2014) Florian Heigwer et al.   NATURE METHODS

A model for the generation and interconversion of ER morphologies

(2014) Tom Shemesh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation

(2013) Yonka Christova et al.   EMBO REPORTS

Endoplasmic reticulum–endosome contact increases as endosomes traffic and mature

(2013) Jonathan R. Friedman et al.   MOLECULAR BIOLOGY OF THE CELL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

A Conserved Role for Atlastin GTPases in Regulating Lipid Droplet Size

(2013) Robin W. Klemm et al.   Cell Reports

Presenilins and  -Secretase: Structure, Function, and Role in Alzheimer Disease

(2013) B. De Strooper et al.   Cold Spring Harbor Perspectives in Medicine

Palmitoylated calnexin is a key component of the ribosome-translocon complex

(2012) Asvin KK Lakkaraju et al.   EMBO JOURNAL

Progressive sheet-to-tubule transformation is a general mechanism for endoplasmic reticulum partitioning in dividing mammalian cells

(2012) Maija Puhka et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquitin-Dependent Intramembrane Rhomboid Protease Promotes ERAD of Membrane Proteins

(2012) Lina Fleig et al.   MOLECULAR CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Weaving the Web of ER Tubules

(2011) Junjie Hu et al.   CELL

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Mechanisms Determining the Morphology of the Peripheral ER

(2010) Yoko Shibata et al.   CELL

ER sliding dynamics and ER–mitochondrial contacts occur on acetylated microtubules

(2010) Jonathan R. Friedman et al.   JOURNAL OF CELL BIOLOGY

Induction of Liver Steatosis and Lipid Droplet Formation in ATF6α-Knockout Mice Burdened with Pharmacological Endoplasmic Reticulum Stress

(2010) Keisuke Yamamoto et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane expansion alleviates endoplasmic reticulum stress independently of the unfolded protein response

(2009) Sebastian Schuck et al.   JOURNAL OF CELL BIOLOGY

Cisternal Organization of the Endoplasmic Reticulum during Mitosis

(2009) Lei Lu et al.   MOLECULAR BIOLOGY OF THE CELL

Homotypic fusion of ER membranes requires the dynamin-like GTPase Atlastin

(2009) Genny Orso et al.   NATURE

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

The Reticulon and Dp1/Yop1p Proteins Form Immobile Oligomers in the Tubular Endoplasmic Reticulum

(2008) Yoko Shibata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY