Targeting β-catenin in hepatocellular cancers induced by coexpression of mutant β-catenin and K-Ras in mice

Postponing the Hypoglycemic Response to Partial Hepatectomy Delays Mouse Liver Regeneration

(2016) Jiansheng Huang et al.   AMERICAN JOURNAL OF PATHOLOGY

The global decrease in cancer mortality: trends and disparities

(2016) D. Hashim et al.   ANNALS OF ONCOLOGY

Annual Report to the Nation on the Status of Cancer, 1975-2012, featuring the increasing incidence of liver cancer

(2016) A. Blythe Ryerson et al.   CANCER

Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point-mutant β-catenin

(2016) Junyan Tao et al.   HEPATOLOGY

Direct Pharmacological Inhibition of  -Catenin by RNA Interference in Tumors of Diverse Origin

(2016) S. Ganesh et al.   MOLECULAR CANCER THERAPEUTICS

Nanotechnological carriers for cancer chemotherapy: The state of the art

(2015) Marilene Estanqueiro et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

The Ras/MAPK pathway and hepatocarcinoma: pathogenesis and therapeutic implications

(2015) Bénédicte Delire et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

β-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis

(2015) Satdarshan Pal Monga   GASTROENTEROLOGY

Genetic Landscape and Biomarkers of Hepatocellular Carcinoma

(2015) Jessica Zucman-Rossi et al.   GASTROENTEROLOGY

Complete response of Ctnnb1-mutated tumours to β-catenin suppression by locked nucleic acid antisense in a mouse hepatocarcinogenesis model

(2015) Evan Delgado et al.   JOURNAL OF HEPATOLOGY

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

(2015) Saverio Tardito et al.   NATURE CELL BIOLOGY

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

(2015) Kornelius Schulze et al.   NATURE GENETICS

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice

(2015) Salvatore Delogu et al.   Oncotarget

Hydrodynamic Transfection for Generation of Novel Mouse Models for Liver Cancer Research

(2014) Xin Chen et al.   AMERICAN JOURNAL OF PATHOLOGY

Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts

(2014) M Chiu et al.   BRITISH JOURNAL OF CANCER

 -Catenin Activation in a Novel Liver Progenitor Cell Type Is Sufficient to Cause Hepatocellular Carcinoma and Hepatoblastoma

(2014) S. Mokkapati et al.   CANCER RESEARCH

Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer

(2014) Supriya K. Saha et al.   NATURE

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

(2014) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Role of Leukocyte Cell-Derived Chemotaxin 2 as a Biomarker in Hepatocellular Carcinoma

(2014) Hirohisa Okabe et al.   PLoS One

KrasG12D and p53 Mutation Cause Primary Intrahepatic Cholangiocarcinoma

(2012) M. R. O'Dell et al.   CANCER RESEARCH

Oncogenic β-catenin triggers an inflammatory response that determines the aggressiveness of hepatocellular carcinoma in mice

(2012) Marie Anson et al.   JOURNAL OF CLINICAL INVESTIGATION

L-Asparaginase and Inhibitors of Glutamine Synthetase Disclose Glutamine Addiction of β-Catenin-Mutated Human Hepatocellular Carcinoma Cells

(2011)   CURRENT CANCER DRUG TARGETS

AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2,

(2011) Coral Ho et al.   HEPATOLOGY

The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation

(2011) Michelle C. Mendoza et al.   TRENDS IN BIOCHEMICAL SCIENCES

Accelerated liver regeneration and hepatocarcinogenesis in mice overexpressing serine-45 mutant β-catenin

(2010) Kari N. Nejak-Bowen et al.   HEPATOLOGY

Integrative Transcriptome Analysis Reveals Common Molecular Subclasses of Human Hepatocellular Carcinoma

(2009) Y. Hoshida et al.   CANCER RESEARCH

β-Catenin Regulates Vitamin C Biosynthesis and Cell Survival in Murine Liver

(2009) Kari N. Nejak-Bowen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo

(2009) Pippa Newell et al.   JOURNAL OF HEPATOLOGY

Ras oncogenes: split personalities

(2008) Antoine E. Karnoub et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY