The Time-Course of Antioxidant Irisin Activity: Role of the Nrf2/HO-1/HMGB1 Axis

Epigallocatechin 3-Gallate Has a Neuroprotective Effect in Retinas of Rabbits with Ischemia/Reperfusion through the Activation of Nrf2/HO-1

(2020) Josué Rivera-Pérez et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification of irisin as a therapeutic agent that inhibits oxidative stress and fibrosis in a murine model of chronic pancreatitis

(2020) Yifan Ren et al.   BIOMEDICINE & PHARMACOTHERAPY

Irisin as a Multifunctional Protein: Implications for Health and Certain Diseases

(2019) Paulina Korta et al.   Medicina-Lithuania

Self-defense of macrophages against oxidative injury: Fighting for their own survival

(2019) László Virág et al.   Redox Biology

Superiority of the Non-Glycosylated Form Over the Glycosylated Form of Irisin in the Attenuation of Adipocytic Meta-Inflammation: A Potential Factor in the Fight Against Insulin Resistance

(2019) Mazur-Bialy   Biomolecules

HMGB1 participates in LPS‑induced acute lung injury by�activating the AIM2 inflammasome in macrophages�and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF‑κB signaling pathways

(2019) Jing Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Role of Catalase in Oxidative Stress- and Age-Associated Degenerative Diseases

(2019) Ankita Nandi et al.   Oxidative Medicine and Cellular Longevity

The macrophage heme-heme oxygenase-1 system and its role in inflammation

(2018) Vijith Vijayan et al.   BIOCHEMICAL PHARMACOLOGY

The mitochondrial respiratory chain: A metabolic rheostat of innate immune cell-mediated antibacterial responses

(2018) Leif E. Sander et al.   MITOCHONDRION

Nrf2 activation and down-regulation of HMGB1 and MyD88 expression by amnion membrane extracts in response to the hypoxia-induced injury in cardiac H9c2 cells

(2018) Yousef Faridvand et al.   BIOMEDICINE & PHARMACOTHERAPY

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

(2018) Hyeonwoo Kim et al.   CELL

Downregulation of HMGB1 is required for the protective role of Nrf2 in EMT-mediated PF

(2018) Jiao Qu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Irisin alleviates liver ischemia-reperfusion injury by inhibiting excessive mitochondrial fission, promoting mitochondrial biogenesis and decreasing oxidative stress

(2018) Jianbin Bi et al.   Redox Biology

The Phagocytic Function of Macrophage-Enforcing Innate Immunity and Tissue Homeostasis

(2017) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Anti-Inflammatory Properties of Irisin, Mediator of Physical Activity, Are Connected with TLR4/MyD88 Signaling Pathway Activation

(2017) Agnieszka Irena Mazur-Bialy et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macrophages in oxidative stress and models to evaluate the antioxidant function of dietary natural compounds

(2017) Omir Adrian Castaneda et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Irisin acts as a regulator of macrophages host defense

(2017) Agnieszka Irena Mazur-Bialy   LIFE SCIENCES

Hydrogen Gas Protects Against Intestinal Injury in Wild Type But Not NRF2 Knockout Mice With Severe Sepsis by Regulating HO-1 and HMGB1 Release

(2017) Yang Yu et al.   SHOCK

The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases

(2016) Hor-Yue Tan et al.   Oxidative Medicine and Cellular Longevity

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

(2016) Eri H. Kobayashi et al.   Nature Communications

Irisin protects against endothelial injury and ameliorates atherosclerosis in apolipoprotein E-Null diabetic mice

(2015) Junyan Lu et al.   ATHEROSCLEROSIS

Beta-1-Adrenergic Receptors Mediate Nrf2-HO-1-HMGB1 Axis Regulation to Attenuate Hypoxia/Reoxygenation-Induced Cardiomyocytes Injury in Vitro

(2015) Jichun Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Higenamine regulates Nrf2-HO-1-Hmgb1 axis and attenuates intestinal ischemia–reperfusion injury in mice

(2015) Chao Liu et al.   INFLAMMATION RESEARCH

Oxidative stress-mediated HMGB1 biology

(2015) Yan Yu et al.   Frontiers in Physiology

Nrf-2–HO-1–HMGB1 axis: An important therapeutic approach for protection against myocardial ischemia and reperfusion injury

(2014) Jichun Wang et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Are Reactive Oxygen Species Always Detrimental to Pathogens?

(2013) Claudia N. Paiva et al.   ANTIOXIDANTS & REDOX SIGNALING

Induction of HO-1 through p38 MAPK/Nrf2 signaling pathway by ethanol extract of Inula helenium L. reduces inflammation in LPS-activated RAW 264.7 cells and CLP-induced septic mice

(2013) Eun Jung Park et al.   FOOD AND CHEMICAL TOXICOLOGY

Glutathione Peroxidase-1 Primes Pro-Inflammatory Cytokine Production after LPS Challenge In Vivo

(2012) Steven Bozinovski et al.   PLoS One

Regulation of Redox Signaling by Selenoproteins

(2010) Wayne Chris Hawkes et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

HMGB1, a potent proinflammatory cytokine in sepsis

(2010) Wenchang Huang et al.   CYTOKINE

Heme-Oxygenase-1 Induction and Carbon Monoxide-Releasing Molecule Inhibit Lipopolysaccharide (LPS)-Induced High-Mobility Group Box 1 Release in Vitro and Improve Survival of Mice in LPS- and Cecal Ligation and Puncture-Induced Sepsis Model in Vivo

(2009) K. Tsoyi et al.   MOLECULAR PHARMACOLOGY

Glutathione peroxidase family - an evolutionary overview

(2008) Rogerio Margis et al.   FEBS Journal