Combination of melatonin and irisin ameliorates lipopolysaccharide‐induced cardiac dysfunction through suppressing the Mst1–JNK pathways

Pericardial fluid: an underrated molecular library of heart conditions and a potential vehicle for cardiac therapy

(2019) Fábio Trindade et al.   BASIC RESEARCH IN CARDIOLOGY

Sepsis-related myocardial injury is associated with Mst1 upregulation, mitochondrial dysfunction and the Drp1/F-actin signaling pathway

(2019) Xiuling Shang et al.   JOURNAL OF MOLECULAR HISTOLOGY

Mst1 inhibition attenuates non-alcoholic fatty liver disease via reversing Parkin-related mitophagy

(2019) Tao Zhou et al.   Redox Biology

Blocking the IL-1β signalling pathway prevents chronic viral myocarditis and cardiac remodeling

(2019) Lisa Kraft et al.   BASIC RESEARCH IN CARDIOLOGY

Acute and chronic remote ischemic conditioning attenuate septic cardiomyopathy, improve cardiac output, protect systemic organs, and improve mortality in a lipopolysaccharide-induced sepsis model

(2019) Takashi Honda et al.   BASIC RESEARCH IN CARDIOLOGY

The different response of cardiomyocytes and cardiac fibroblasts to mitochondria inhibition and the underlying role of STAT3

(2019) Jing Zhao et al.   BASIC RESEARCH IN CARDIOLOGY

Remote ischaemic preconditioning ameliorates sinus rhythm restoration rate through Cox maze radiofrequency procedure associated with inflammation reaction reduction

(2019) Qin Jiang et al.   BASIC RESEARCH IN CARDIOLOGY

Things get broken: the hypoxia-inducible factor prolyl hydroxylases in ischemic heart disease

(2019) Timm Schreiber et al.   BASIC RESEARCH IN CARDIOLOGY

Protection against cardiac ischemia-reperfusion injury by hypothermia and by inhibition of succinate accumulation and oxidation is additive

(2019) M. Kohlhauer et al.   BASIC RESEARCH IN CARDIOLOGY

Atrial fibrillation is associated with alterations in HDL function, metabolism, and particle number

(2019) Markus Trieb et al.   BASIC RESEARCH IN CARDIOLOGY

Reduced ambient temperature exacerbates SIRS-induced cardiac autonomic dysregulation and myocardial dysfunction in mice

(2019) Bernadin Ndongson-Dongmo et al.   BASIC RESEARCH IN CARDIOLOGY

Irisin ameliorates septic cardiomyopathy via inhibiting DRP1-related mitochondrial fission and normalizing the JNK-LATS2 signaling pathway

(2019) Ying Tan et al.   CELL STRESS & CHAPERONES

Blockade of AMPA Receptor Regulates Mitochondrial Dynamics by Modulating ERK1/2 and PP1/PP2A-Mediated DRP1-S616 Phosphorylations in the Normal Rat Hippocampus

(2019) Ji-Eun Kim et al.   Frontiers in Cellular Neuroscience

Therapeutic contribution of melatonin to the treatment of septic cardiomyopathy: A novel mechanism linking Ripk3-modified mitochondrial performance and endoplasmic reticulum function

(2019) Jiankai Zhong et al.   Redox Biology

Enhancement of cardiac lymphangiogenesis by transplantation of CD34+VEGFR-3+ endothelial progenitor cells and sustained release of VEGF-C

(2019) Hai-feng Zhang et al.   BASIC RESEARCH IN CARDIOLOGY

Coronary microvascular obstruction: the new frontier in cardioprotection

(2019) Gerd Heusch   BASIC RESEARCH IN CARDIOLOGY

Glucocorticoids preserve the t-tubular system in ventricular cardiomyocytes by upregulation of autophagic flux

(2019) Thomas Seidel et al.   BASIC RESEARCH IN CARDIOLOGY

Therapies to limit myocardial injury in animal models of myocarditis: a systematic review and meta-analysis

(2019) Joshua A. Silverblatt et al.   BASIC RESEARCH IN CARDIOLOGY

BI1 is associated with microvascular protection in cardiac ischemia reperfusion injury via repressing Syk–Nox2–Drp1-mitochondrial fission pathways

(2018) Hao Zhou et al.   ANGIOGENESIS

DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway

(2018) Yoshinobu Saito et al.   CELL DEATH AND DIFFERENTIATION

The Ectodysplasin receptor EDAR acts as a tumor suppressor in melanoma by conditionally inducing cell death

(2018) Jonathan Vial et al.   CELL DEATH AND DIFFERENTIATION

SREBP1, targeted by miR-18a-5p, modulates epithelial-mesenchymal transition in breast cancer via forming a co-repressor complex with Snail and HDAC1/2

(2018) Ning Zhang et al.   CELL DEATH AND DIFFERENTIATION

p73 coordinates with Δ133p53 to promote DNA double-strand break repair

(2018) Hongjian Gong et al.   CELL DEATH AND DIFFERENTIATION

Exploring the genetics and non-cell autonomous mechanisms underlying ALS/FTLD

(2018) Hongbo Chen et al.   CELL DEATH AND DIFFERENTIATION

Sex disparity in cancer: roles of microRNAs and related functional players

(2018) Alessandra Carè et al.   CELL DEATH AND DIFFERENTIATION

Orai3 calcium channel and resistance to chemotherapy in breast cancer cells: the p53 connection

(2018) Jessy Hasna et al.   CELL DEATH AND DIFFERENTIATION

Enhanced PAPSS2/VCAN sulfation axis is essential for Snail-mediated breast cancer cell migration and metastasis

(2018) Yihong Zhang et al.   CELL DEATH AND DIFFERENTIATION

Mammalian endoreplication emerges to reveal a potential developmental timer

(2018) Alberto Gandarillas et al.   CELL DEATH AND DIFFERENTIATION

Melatonin therapy for diabetic cardiomyopathy: A mechanism involving Syk-mitochondrial complex I-SERCA pathway

(2018) Hao Zhou et al.   CELLULAR SIGNALLING

Irisin Protects Heart Against Ischemia-Reperfusion Injury Through a SOD2-Dependent Mitochondria Mechanism

(2018) Zhen Wang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Mst1 promotes cardiac ischemia–reperfusion injury by inhibiting the ERK-CREB pathway and repressing FUNDC1-mediated mitophagy

(2018) Wancheng Yu et al.   Journal of Physiological Sciences

A unified model of melatonin, 6-sulfatoxymelatonin, and sleep dynamics

(2018) Romesh G. Abeysuriya et al.   JOURNAL OF PINEAL RESEARCH

Inhibitory effect of melatonin on necroptosis via repressing the Ripk3-PGAM5-CypD-mPTP pathway attenuates cardiac microvascular ischemia-reperfusion injury

(2018) Hao Zhou et al.   JOURNAL OF PINEAL RESEARCH

Diabetic retinopathy pathogenesis and the ameliorating effects of melatonin; involvement of autophagy, inflammation and oxidative stress

(2018) Ehsan Dehdashtian et al.   LIFE SCIENCES

Prolonged oxidative stress down-regulates Early B cell factor 1 with inhibition of its tumor suppressive function against cholangiocarcinoma genesis

(2018) Napat Armartmuntree et al.   Redox Biology

Metformin selectively targets redox control of complex I energy transduction

(2018) Amy R. Cameron et al.   Redox Biology

Redox system and phospholipid metabolism in the kidney of hypertensive rats after FAAH inhibitor URB597 administration

(2018) Michał Biernacki et al.   Redox Biology

Mitochondrial dysfunction in Parkinsonian mesenchymal stem cells impairs differentiation

(2018) Plamena R. Angelova et al.   Redox Biology

8-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions

(2018) Xueqing Ba et al.   Redox Biology

Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: A mechanism involving calcium overload/XO/ROS/mPTP pathway

(2018) Pingjun Zhu et al.   Redox Biology

Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission

(2018) Hao Zhou et al.   Redox Biology

Yap promotes hepatocellular carcinoma metastasis and mobilization via governing cofilin/F-actin/lamellipodium axis by regulation of JNK/Bnip3/SERCA/CaMKII pathways

(2018) Chen Shi et al.   Redox Biology

Raf kinase inhibitor protein mediates myocardial fibrosis under conditions of enhanced myocardial oxidative stress

(2018) Andrey Kazakov et al.   BASIC RESEARCH IN CARDIOLOGY

Mechanisms underlying coronary autoregulation continue to await clarification

(2018) Andreas Deussen   BASIC RESEARCH IN CARDIOLOGY

Local metabolic hypothesis is not sufficient to explain coronary autoregulatory behavior

(2018) Alexander M. Kiel et al.   BASIC RESEARCH IN CARDIOLOGY

Intravenous miR-144 reduces left ventricular remodeling after myocardial infarction

(2018) Jing Li et al.   BASIC RESEARCH IN CARDIOLOGY

Increased cardiac sympathetic nerve activity in ovine heart failure is reduced by lesion of the area postrema, but not lamina terminalis

(2018) Yonis Abukar et al.   BASIC RESEARCH IN CARDIOLOGY

Practical guidelines for rigor and reproducibility in preclinical and clinical studies on cardioprotection

(2018) Hans Erik Bøtker et al.   BASIC RESEARCH IN CARDIOLOGY

LXR/RXR signaling and neutrophil phenotype following myocardial infarction classify sex differences in remodeling

(2018) Kristine Y. DeLeon-Pennell et al.   BASIC RESEARCH IN CARDIOLOGY

Paracrine signalling during ZEB1-mediated epithelial–mesenchymal transition augments local myofibroblast differentiation in lung fibrosis

(2018) Liudi Yao et al.   CELL DEATH AND DIFFERENTIATION

Activation of S6 signaling is associated with cell survival and multinucleation in hyperplastic skin after epidermal loss of AURORA-A Kinase

(2018) Weston Kenneth Ryan et al.   CELL DEATH AND DIFFERENTIATION

Innate immune adaptor MyD88 deficiency prevents skin inflammation in SHARPIN-deficient mice

(2018) Bhesh Raj Sharma et al.   CELL DEATH AND DIFFERENTIATION

Superhero Rictor promotes cellular differentiation of mouse embryonic stem cells

(2018) Youming Zhu et al.   CELL DEATH AND DIFFERENTIATION

BI1 alleviates cardiac microvascular ischemia-reperfusion injury via modifying mitochondrial fission and inhibiting XO/ROS/F-actin pathways

(2018) Hao Zhou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Mst1 knockout enhances cardiomyocyte autophagic flux to alleviate angiotensin II-induced cardiac injury independent of angiotensin II receptors

(2018) Zheng Cheng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Irisin alleviates pressure overload-induced cardiac hypertrophy by inducing protective autophagy via mTOR-independent activation of the AMPK-ULK1 pathway

(2018) Ru-Li Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Inflammatory cells and their non-coding RNAs as targets for treating myocardial infarction

(2018) Mira Jung et al.   BASIC RESEARCH IN CARDIOLOGY

Uncoupling protein 3 deficiency impairs myocardial fatty acid oxidation and contractile recovery following ischemia/reperfusion

(2018) Kristin S. Edwards et al.   BASIC RESEARCH IN CARDIOLOGY

Purinergic receptor Y2 (P2Y2)- dependent VCAM-1 expression promotes immune cell infiltration in metabolic syndrome

(2018) Julian Merz et al.   BASIC RESEARCH IN CARDIOLOGY

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection—evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology

(2018) Sean M. Davidson et al.   BASIC RESEARCH IN CARDIOLOGY

Ophiopogonin B induces the autophagy and apoptosis of colon cancer cells by activating JNK/c-Jun signaling pathway

(2018) Guang-Yi Gao et al.   BIOMEDICINE & PHARMACOTHERAPY

Cardiac-specific Mst1 deficiency inhibits ROS-mediated JNK signalling to alleviate Ang II-induced cardiomyocyte apoptosis

(2018) Zheng Cheng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lipoproteins as targets and markers of lipoxidation

(2018) Catarina B. Afonso et al.   Redox Biology

MnSOD is implicated in accelerated wound healing upon Negative Pressure Wound Therapy (NPWT): A case in point for MnSOD mimetics as adjuvants for wound management

(2018) Gregory Lucien Bellot et al.   Redox Biology

A high-throughput real-time in vitro assay using mitochondrial targeted roGFP for screening of drugs targeting mitochondria

(2018) Aneesh Chandrasekharan et al.   Redox Biology

Proteasome lid bridges mitochondrial stress with Cdc53/Cullin1 NEDDylation status

(2018) L. Bramasole et al.   Redox Biology

Metabolic syndrome and cancer risk: The role of xanthine oxidoreductase

(2018) Maria Giulia Battelli et al.   Redox Biology

Dynamin-related protein 1-mediated mitochondrial fission contributes to post-traumatic cardiac dysfunction in rats and the protective effect of melatonin

(2017) Mingge Ding et al.   JOURNAL OF PINEAL RESEARCH

Melatonin Alleviates Intracerebral Hemorrhage-Induced Secondary Brain Injury in Rats via Suppressing Apoptosis, Inflammation, Oxidative Stress, DNA Damage, and Mitochondria Injury

(2017) Zhong Wang et al.   Translational Stroke Research

Mff‐Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS‐Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation‐Involved mPTP Opening

(2017) Hao Zhou et al.   Journal of the American Heart Association

Gefitinib enhances human colon cancer cells to TRAIL-induced apoptosis of via autophagy- and JNK-mediated death receptors upregulation

(2016) Lei Chen et al.   APOPTOSIS

Myocardial apoptosis in heart disease: does the emperor have clothes?

(2016) J. Jose Corbalan et al.   BASIC RESEARCH IN CARDIOLOGY

p38α MAPK inhibits stretch-induced JNK activation in cardiac myocytes through MKP-1

(2016) Hao Feng et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Cardiomyocyte death: mechanisms and translational implications

(2011) M Chiong et al.   Cell Death & Disease

Role of apoptosis in cardiovascular disease

(2009) Youngil Lee et al.   APOPTOSIS