Article
Biochemistry & Molecular Biology
Bingren Tian, Wanrong Li, Jie Wang, Yumei Liu
Summary: In this study, beta-acids/chitosan complex films were successfully prepared and characterized. The films showed improved mechanical strength, antimicrobial properties, and excellent UV barrier capability, making them a promising alternative for active packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Bingren Tian, Jie Wang, Qiang Liu, Yumei Liu, Dejun Chen
Summary: By modifying the preparation method of hydrogel films, this study successfully improved the physical properties and antibacterial activity of the films. The introduction of nano-silica in different ways had a significant impact on the tensile strength of the films. Additionally, the loading of beta-acids not only blocked ultraviolet rays but also exhibited inhibitory effects on bacteria.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Applied
Bingren Tian, Dan Xu, Jianhua Cheng, Yumei Liu
Summary: This study improved the properties of chitosan films by adding silica and beta-acids, resulting in significant tensile strength, antimicrobial effects, and antioxidant activity. The release mechanism of beta-acids from the films exhibited Fickian diffusion, effectively controlling changes in soybean oil and prolonging food storage time.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Applied
Chunhua Wu, Zijian Zhi, Mengxia Duan, Jishuang Sun, Haixin Jiang, Jie Pang
Summary: Nisin-loaded carboxymethyl chitosan nanogels (CN NGs) were prepared through a combination method of electrostatic self-assembly and chemical cross-linking, demonstrating good dispersion and spherical structure. The main driving force in the formation of CN NGs was found to be the electrostatic interactions and hydrogen bonding between nisin and CMCS. Additionally, the CN NGs exhibited controlled release behavior of nisin and excellent antimicrobial activity, indicating their potential as a bio-preservative in the food industry.
Article
Chemistry, Physical
Hui Yun Zhou, Pei Yan Hao, Shuai Qiang Jiang, Wan Hui Zhang, Li Jun Ren, Hui Jie Zheng, Ya Wei Chen, Jun Liang Chen, Hyun Jin Park
Summary: In this paper, cyclodextrin-grafted-chitosan (CD-g-CS) with different degrees of substitution (DS) was successfully synthesized for the development of an injectable thermosensitive hydrogel. The hydrogel showed rapid gelation and had a three-dimensional porous structure. It exhibited good swelling ratio, degradable behavior, sustained drug release, and excellent antibacterial activity against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli). The CD-g-CS/GP-SHC hydrogels have great potential in biomedical drug delivery systems and antibacterial materials.
JOURNAL OF MOLECULAR STRUCTURE
(2024)
Article
Polymer Science
Dan Xu, Ting Chen, Yumei Liu
Summary: The study developed active films based on blends of gelatin and/or chitosan with different bioactive agents, showing improved mechanical properties and better UV light barrier properties with the addition of bioactive agents. The films exhibited strong antioxidant and antimicrobial activities, especially against Gram-positive bacteria, indicating potential for food preservation and safety. Interaction between bioactive agents and biopolymers was confirmed by FTIR analysis.
Article
Biochemistry & Molecular Biology
Yanzhen Zhao, Liu Yang, Meirong Xu, Huifang Wang, Xianghua Gao, Baolong Niu, Wenfeng Li
Summary: In this study, silver nanoparticles were reduced and immobilized in situ using gallic acid-functionalized chitosan to achieve a long-lasting and stable controlled release of silver ions. The CG/PVA/AgNPs composite film demonstrated persistent antibacterial effects and improved freshness preservation, showing potential as an effective and safe packaging material to extend the shelf life of food products.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Materials Science, Coatings & Films
Anike H. Virgili, Daniela C. Laranja, Patricia S. Malheiros, Marcelo B. Pereira, Tania M. H. Costa, Eliana W. de Menezes
Summary: This study investigated the role of APTMS in the chitosan-gold nanoparticles system, finding that its addition significantly decreased the system's dynamic viscosity, contributing to greater miscibility, and evaluated antimicrobial activity through the construction of a gold nanoparticle film.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Chemistry, Medicinal
Sivarasan Ganesan, Jagadeesh Kumar Alagarasan, Mohandoss Sonaimuthu, Kanakaraj Aruchamy, Fatemah Homoud Alkallas, Amira Ben Gouider Trabelsi, Fedor Vasilievich Kusmartsev, Veerababu Polisetti, Moonyong Lee, Huang-Mu Lo
Summary: This study formulated and characterized salsalate-loaded chitosan nanoparticles prepared using the ionic gelation method and investigated their release behavior, antibacterial activity, and ability to inhibit biofilm production. The optimized nanoparticles showed sustained drug release and exhibited excellent antibacterial and antibiofilm activities. CSNPs could be a promising dosage form for sustained drug delivery and enhanced therapeutic effects.
Article
Materials Science, Ceramics
Pei Yan Hao, Hui Yun Zhou, Li Jun Ren, Hui Jie Zheng, Jia Nan Tong, Ya Wei Chen, Hyun Jin Park
Summary: In this study, the β-cyclodextrin-grafted chitosan/glycerophosphate (CD-g-CS/GP) hydrogels were successfully synthesized and exhibited great potential for the controlled release of hydrophobic drugs. The hydrogels had a short gelation time, superior injection performance, suitable swelling behavior, and enhanced solubility and bioavailability of curcumin. Furthermore, the hydrogels showed good hemocompatibility and antibacterial activity against Staphylococcus aureus and Escherichia coli.
JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Pascale Chevallier, Helton Jose Wiggers, Francesco Copes, Cecilia Zorzi Bueno, Diego Mantovani
Summary: Healthcare-associated infections (HAIs) are a global burden, causing significant mortality and financial costs. Microbiological contamination of implantable medical devices is an important cause of HAIs. A novel antimicrobial drug-eluting system was developed using chitosan and loaded with gentamicin, a broad-spectrum antibiotic. The addition of tannic acid and iron decreased swelling and degradation, resulting in sustained gentamicin release for up to 35 days.
Article
Biochemistry & Molecular Biology
Hossein Ghasemzadeh, Shiravan Afraz, Mohadeseh Moradi, Samira Hassanpour
Summary: The study focuses on the production and characterization of antibacterial and biocompatible films made from chitosan and agarose, as well as the structural analysis of activated agarose. The research demonstrates the potential of these films for applications in food packaging and wound healing due to their strong antibacterial properties against gram-negative and gram-positive bacteria.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biochemistry & Molecular Biology
Lingyu Zhang, Zhaoyu Zhang, Chengpeng Li, Zhang Hu, Youling Liang, Ziming Yang, Yu Cheng, Dejian Huang
Summary: The study successfully synthesized the PACSC-I composite film and tested its various properties, showing good physicochemical properties and biocompatibility. The composite film exhibited excellent antibacterial activity and controlled release of iodine, promising applications as antibacterial material in the medical field.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Biochemistry & Molecular Biology
Hao Gong, Li Liu, Jieru Zhou, Helin Li, Jiaxing Qiu, Weini Cheng
Summary: In recent years, antibiotic-resistant bacteria have become a global problem due to the irrational use of antibiotics. Few studies have introduced customized antibacterial nanoplatforms to combat antibiotic resistance based on the specific characteristics of bacteria, instead of relying on the abuse of antibiotics. Therefore, we have designed a novel antibiotic delivery nanocarrier composed of polyaniline-grafted-chitosan, which exhibits pH-responsive, conductive, photothermal, and biodegradable properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Ioana-Victoria Platon, Claudiu-Augustin Ghiorghita, Maria Marinela Lazar, Irina Elena Raschip, Maria Valentina Dinu
Summary: New chitosan sponges with multiple functions were prepared by glutaraldehyde cross-linking and showed excellent antibacterial, antioxidant, and controlled delivery properties. The sponges exhibited complete shape recovery after compression, effective antibacterial activity against different strains, and good radical scavenging activity. The release of curcumin from the sponges relied on their composition and preparation strategy, and a pseudo-Fickian diffusion release mechanism was observed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Chemistry, Applied
Bingren Tian, Shiyao Hua, Jiayue Liu
CARBOHYDRATE POLYMERS
(2020)
Review
Agriculture, Multidisciplinary
Bingren Tian, Jiayue Liu
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2020)
Review
Polymer Science
Bingren Tian, Dong Xiao, Tingting Hei, Rui Ping, Shiyao Hua, Jiayue Liu
POLYMER INTERNATIONAL
(2020)
Review
Chemistry, Applied
Bingren Tian, Yumei Liu, Jiayue Liu
CARBOHYDRATE POLYMERS
(2020)
Review
Chemistry, Applied
Bingren Tian, Yumei Liu, Jiayue Liu
Summary: Research in materials chemistry and medicine has led to the development of advanced drug delivery systems based on stimuli-responsive cyclodextrin. These systems respond to different stimuli such as pH, light, temperature, magnet, redox, and enzymes. Current research focuses on the classification, characteristics, and applications of these smart drug delivery systems.
CARBOHYDRATE POLYMERS
(2021)
Review
Polymer Science
Bingren Tian, Yumei Liu
POLYMERS FOR ADVANCED TECHNOLOGIES
(2020)
Review
Environmental Sciences
Bingren Tian, Shiyao Hua, Yu Tian, Jiayue Liu
Summary: Cyclodextrin derivatives are regarded as a new generation of adsorbents with significant effects in treating wastewater. Different pollutants are influenced by various types of cyclodextrin-based adsorbents. Furthermore, cost-effectiveness and regeneration performance of cyclodextrin-based adsorbents are also highlighted.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Materials Science, Ceramics
Bingren Tian, Yumei Liu
Summary: This paper reviews the advantages, safety issues, and applications of silica-based antibacterial materials, highlighting the preparation, application, and antimicrobial efficiency of materials with different structure/size. It also outlines the possible antimicrobial mechanisms of silica-based materials and potential challenges for researchers. Additionally, corresponding antibacterial material preparation strategies are proposed in response to increasing concerns regarding bacterial contamination in the food and medical industries.
INTERNATIONAL JOURNAL OF APPLIED CERAMIC TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Bingren Tian, Wanrong Li, Jie Wang, Yumei Liu
Summary: In this study, beta-acids/chitosan complex films were successfully prepared and characterized. The films showed improved mechanical strength, antimicrobial properties, and excellent UV barrier capability, making them a promising alternative for active packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biotechnology & Applied Microbiology
Bingren Tian, Dan Xu, Wanrong Li, Jie Wang, Jianhua Cheng, Yumei Liu
Summary: This study aimed to investigate the regulatory and shaping effects of HBA/HP-beta-CD on the proteome of L. monocytogenes. The results showed that HBA/HP-beta-CD exhibited significant antibacterial activity against L. monocytogenes, and the changes in the proteome were mainly associated with carbohydrate metabolism, protein synthesis, cell wall composition, and cell division.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Review
Biochemistry & Molecular Biology
Jiayue Liu, Bingren Tian, Yumei Liu, Jian-Bo Wan
Summary: Cyclodextrin (CD) can be incorporated into hydrogels to form chemically or physically cross-linked networks, making it an ideal vehicle for delivering active ingredients to target tissues. This review discusses preparation methods, biomedical applications, release and degradation processes of CD-containing hydrogels under different conditions, as well as current challenges and future research directions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Food Science & Technology
Bingren Tian, Jiayue Liu, Yumei Liu, Jian-Bo Wan
Summary: The popularity of plant bioactive ingredients in the food industry is increasing. However, these ingredients have some deficiencies. Cyclodextrins (CDs) have been extensively studied as excellent carriers for plant bioactive ingredients and can be added to film materials to create bioactive food packaging. This review summarizes the extraction methods of plant bioactive ingredients, the addition of CD inclusion compounds to thin-film materials, and their applications in food packaging. The release model and mechanism of active film materials based on various plant bioactive ingredients with CDs are also highlighted.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Materials Science, Biomaterials
Bingren Tian, Shiyao Hua, Yu Tian, Jiayue Liu
JOURNAL OF MATERIALS CHEMISTRY B
(2020)
Review
Chemistry, Multidisciplinary
Jia Yue Liu, Xiao Zhang, Bing Ren Tian
TURKISH JOURNAL OF CHEMISTRY
(2020)
Article
Chemistry, Applied
Deepika Sharma, Gregory R. Ziegler, Federico M. Harte
Summary: Fabrication of bead-free nanofibers from pure casein is challenging due to its self-aggregation tendency. In this study, the influence of pH, ethanol content, ionic environment, and casein concentration on the solubility and solution characteristics of casein-based spinning dopes was analyzed. The addition of tetrasodium pyrophosphate (TSPP) reduced bead defects and improved the properties of the nanofibers. The viscosity of the solution depended on the casein concentration, and bead-free nanofibers were obtained at a concentration higher than the entanglement concentration (C-e).
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Smriti Shrestha, Leonie Van't Hag, Victoria Haritos, Sushil Dhital
Summary: This study investigated the pasting properties, structural formation, and molecular changes of mungbean, green lentil, and yellow pea proteins during high moisture extrusion (HME). The results showed that protein composition and conformation played important roles in the structural development and molecular changes during HME.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Shi Liu, Na Sun, Kunyu Ren, Xubin Tan, Lanxin Li, Zhe Wang, Shicheng Dai, Xiaohong Tong, Huan Wang, Lianzhou Jiang
Summary: In this study, self-assembled soy protein nanoparticles (SPN) were successfully prepared and used for encapsulation of lutein, 8-carotene, and curcumin. The encapsulated natural pigments showed improved stability, especially curcumin. This study provides a new approach for extending the use of lipophilic natural edible pigments in food products.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Jianming Wang, Ziyun Liu, Kaiwen Zheng, Zhe Yuan, Chen Yang
Summary: By combining with high methoxyl pectin (HMP), the emulsifying properties of oat protein isolate (OPI) were improved. The OPI-HMP complex formed soluble complexes under specific pH conditions, exhibiting excellent emulsifying activity and stability, making it suitable as a delivery system for lipid soluble bioactive compounds in food and biomedical applications.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Zihao Yin, Junzhe Zou, Mengwei Wang, Ruonan Huang, Yuemiao Qian, Mingyong Zeng, Fangwei Li
Summary: Phycocyanin, a protein prone to degradation under acidic conditions and unstable at high temperatures, has limited application in food. This study successfully combined phycocyanin with whey protein isolate using protein coprecipitation and chitosan coating to form composite particles, which maintained the color and colloidal stability of phycocyanin. The composite particles showed minimal color changes and retained high pigment retention rates after heating. Furthermore, the composite particles exhibited excellent antioxidant capacity. This breakthrough expands the application of phycocyanin in acidic beverages and other food forms.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Yuting Su, Qian Zhou, Hui Xu, Manting Huang, Siqian Li, Jiayi He, Ka-Wing Cheng, Mingfu Wang
Summary: By developing the CM-Cur/QT complex, the solubility and stability of quercetin were improved, leading to enhanced bioavailability. The complex showed increased bio-accessibility and antioxidant efficacy during in vitro digestion, and facilitated the internalization of quercetin in macrophages, exerting a potential synergistic anti-inflammatory effect.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Sheliang Zhao, David Julian Mcclements, Xuebo Liu, Fuguo Liu
Summary: The low oral bioavailability of some bioactive ingredients is a challenge in the supplement and functional food areas. This study designs natural carriers that can simultaneously deliver both hydrophobic and hydrophilic bioactive ingredients, thereby increasing their ability to exert synergistic effects.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Md Easdani, Shabbir Ahammed, Md Nazmus Saqib, Fei Liu, Fang Zhong
Summary: Compiling hydrophobic and hydrophilic proteins to form a mechanically reliable bilayer film with improved water barrier properties and hydrophobicity is challenging. By introducing cross-linkers, the film exhibits compatible and flexible surfaces, enhanced color and transparency, and controlled water vapor permeability. The bilayer film shows potential for improving value-added functional properties.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Tian-Qi Zhou, Xue-Chen Wang, Ling-Yi Gao, Jia-Nan Yan, Hai-Tao Wu
Summary: This study investigated the synergetic gelation of curdlan gum (CG) and gellan gum (GG) at different ratios. The optimal gelation was achieved at a mass ratio of 1:1 and a total concentration of 0.6%. The gel properties were influenced by the CG/GG ratio, with the strongest gel observed at a ratio of 5:5. The improved gel properties were attributed to hydrogen bonds between CG and GG. The CG/GG binary composite gel exhibited increased water holding capacity as the CG/GG ratio decreased. Furthermore, the microstructure of the CG/GG gel was denser and more homogeneous, supporting its stronger gel rigidity and water holding capacity.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Jialin Sun, Zihao Wei, Changhu Xue
Summary: In this study, porous gelatin microspheres (PGMs) with surface and internal porous structure were developed for the controlled release and rapid functional response of anthocyanins (ANCs). The loading of ACNs was achieved through electrostatic interaction, resulting in a high loading capacity. ACN@PGMs exhibited long-term controlled release, improved storage stability, and ammonia responsiveness, making them suitable for applications as antioxidant factors and food freshness indicators in the food industry.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Xinlai Dou, Yanling Hao, Ying Sun, Pin Yang, Linlin Liu, Yinyuan He, Yanguo Shi, Chunhua Yang, Fenglian Chen
Summary: In this study, chitosan hydrochloride/carboxymethyl starch sodium (CHC-CMS-Na) nanogels were prepared as a baking additive and showed potential in improving bread quality.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Xinya Wang, H. Douglas Goff, Steve W. Cui
Summary: This study thoroughly investigated the synergistic gelation between yellow mustard gum (YMG) and kappa-carrageenan using multiple techniques. The results showed that the interaction between YMG and kappa-carrageenan was mainly polymer associations, and YMG affected the gel formation process of kappa-carrageenan.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Jielong Zhang, Dasong Liu, Xiumei Tao, Jun Tang, Xiaoyu Peng, Thom Huppertz, Xiaoming Liu, Peng Zhou
Summary: The effect of enzymatic dephosphorylation on the structure of casein micelles in caprine micellar casein concentrate was studied. The results showed that with increasing dephosphorylation, the molar mass decreased, the radii decreased, the hydration increased, and the internal protein inhomogeneity disappeared.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Wentao Ma, Chao Yuan, Bo Cui, Tian Gao, Li Guo, Bin Yu, Meng Zhao, Feixue Zou
Summary: This study investigated the influence of highly-branched cyclic dextrin (HBCD) on the physiochemical properties of x-carrageenan (KC) gels. The addition of HBCD significantly enhanced the storage modulus and freeze-thaw stability of KC gels. HBCD promoted the distribution of KC chains and aggregation of KC helixes, resulting in a compact network structure and reduced water loss. Furthermore, HBCD strengthened the thermal reversibility of KC gels through enhanced hydrogen-bonding interactions.
FOOD HYDROCOLLOIDS
(2024)
Article
Chemistry, Applied
Ya-Ru Wang, Qin Yang, Yi-Xuan Jiang, Han-Qing Chen
Summary: This study successfully improved the aqueous solubility, thermal stability, and antioxidant activity of RES by using ovalbumin fibrils as nanocarriers. The pH value was found to have an impact on the formation and properties of the complex, with the best interaction observed at pH 2.0.
FOOD HYDROCOLLOIDS
(2024)