TRIM45 causes neuronal damage by aggravating microglia-mediated neuroinflammation upon cerebral ischemia and reperfusion injury

Annexin-A1 SUMOylation regulates microglial polarization after cerebral ischemia by modulating IKKα stability via selective autophagy

(2021) Xing Li et al.   Science Advances

BK Channel-Mediated Microglial Phagocytosis Alleviates Neurological Deficit After Ischemic Stroke

(2021) Shuxian Huang et al.   Frontiers in Cellular Neuroscience

Inhibition of TRIM8 restrains ischaemia-reperfusion-mediated cerebral injury by regulation of NF-κB activation associated inflammation and apoptosis

(2020) Xue Bai et al.   EXPERIMENTAL CELL RESEARCH

Trim45 is essential to the development of the diencephalon and eye in zebrafish embryos

(2020) Seoyeon Choe et al.   Animal Cells and Systems

Immune responses to stroke: mechanisms, modulation, and therapeutic potential

(2020) Costantino Iadecola et al.   JOURNAL OF CLINICAL INVESTIGATION

Reversal of prolonged obesity-associated cerebrovascular dysfunction by inhibiting microglial Tak1

(2020) Qing Shen et al.   NATURE NEUROSCIENCE

The Local and Peripheral Immune Responses to Stroke: Implications for Therapeutic Development

(2020) Kristy A. Zera et al.   Neurotherapeutics

Glia Crosstalk in Neuroinflammatory Diseases

(2020) Ada Bernaus et al.   Frontiers in Cellular Neuroscience

The ARRIVE guidelines 2.0: Updated guidelines for reporting animal research

(2020) Nathalie Percie du Sert et al.   PLOS BIOLOGY

TRIM proteins

(2019) Milica Vunjak et al.   CURRENT BIOLOGY

Interaction between caspase-3 and caspase-5 in the stretch-induced programmed cell death in the human periodontal ligament cells

(2019) Yaqin Wu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Intracerebroventricular Delivery of Recombinant NAMPT Deters Inflammation and Protects Against Cerebral Ischemia

(2019) Fenghua Chen et al.   Translational Stroke Research

Tribulusterine Containing Tribulus terrestris Extract Exhibited Neuroprotection Through Attenuating Stress Kinases Mediated Inflammatory Mechanism: In Vitro and In Vivo Studies

(2019) R. Ranjithkumar et al.   NEUROCHEMICAL RESEARCH

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice

(2019) Jianxiong Zeng et al.   Cell Reports

Neuroinflammation: friend and foe for ischemic stroke

(2019) Richard L. Jayaraj et al.   Journal of Neuroinflammation

Trim47 is a critical regulator of cerebral ischemia-reperfusion injury through regulating apoptosis and inflammation

(2019) Miao-Qing Hao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cyanidin-3-O-Glucoside Protects PC12 Cells Against Neuronal Apoptosis Mediated by LPS-Stimulated BV2 Microglial Activation

(2019) Chayanut Kaewmool et al.   NEUROTOXICITY RESEARCH

Eicosapentaenoic acid prevents inflammation induced by acute cerebral infarction through inhibition of NLRP3 inflammasome activation

(2019) Zhihuai Mo et al.   LIFE SCIENCES

A novel cell-penetrating peptide protects against neuron apoptosis after cerebral ischemia by inhibiting the nuclear translocation of annexin A1

(2018) Xing Li et al.   CELL DEATH AND DIFFERENTIATION

Molecular mechanisms of Streptococcus pneumoniae -targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination

(2018) Michinaga Ogawa et al.   CELLULAR MICROBIOLOGY

The Innate Immune Receptors TLR2/4 Mediate Repeated Social Defeat Stress-Induced Social Avoidance through Prefrontal Microglial Activation

(2018) Xiang Nie et al.   NEURON

Photobiomodulation prevents DNA fragmentation of alveolar epithelial cells and alters the mRNA levels of caspase 3 and Bcl-2 genes in acute lung injury

(2018) Luiz Philippe da Silva Sergio et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Regulation of RIG-I Activation by K63-Linked Polyubiquitination

(2018) Masaaki Okamoto et al.   Frontiers in Immunology

Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation

(2018) Chan Hee Lee et al.   Cell Reports

Fish antiviral tripartite motif (TRIM) proteins

(2018) Christelle Langevin et al.   FISH & SHELLFISH IMMUNOLOGY

Post-Translational Modifications of the TAK1-TAB Complex

(2017) Yusuke Hirata et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The IMPROVE Guidelines (Ischaemia Models: Procedural Refinements Of in Vivo Experiments)

(2017) Nathalie Percie du Sert et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TRIM Family Proteins: Roles in Autophagy, Immunity, and Carcinogenesis

(2017) Shigetsugu Hatakeyama   TRENDS IN BIOCHEMICAL SCIENCES

Inflammation and the Metabolic Syndrome: The Tissue-Specific Functions of NF-κB

(2017) Leen Catrysse et al.   TRENDS IN CELL BIOLOGY

Pyridoxine 5′-phosphate oxidase is a novel therapeutic target and regulated by the TGF-β signalling pathway in epithelial ovarian cancer

(2017) Lingyun Zhang et al.   Cell Death & Disease

Anti-Inflammatory Targets for the Treatment of Reperfusion Injury in Stroke

(2017) Atsushi Mizuma et al.   Frontiers in Neurology

The ubiquitin E3 ligase TRIM31 promotes aggregation and activation of the signaling adaptor MAVS through Lys63-linked polyubiquitination

(2016) Bingyu Liu et al.   NATURE IMMUNOLOGY

MG53 permeates through blood-brain barrier to protect ischemic brain injury

(2016) Yonggang Yao et al.   Oncotarget

Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Deficiency Attenuates Phagocytic Activities of Microglia and Exacerbates Ischemic Damage in Experimental Stroke

(2015) M. Kawabori et al.   JOURNAL OF NEUROSCIENCE

Immune interventions in stroke

(2015) Ying Fu et al.   Nature Reviews Neurology

Following OGD/R, Annexin 1 Nuclear Translocation and Subsequent Induction of Apoptosis in Neurons Are Assisted by Myosin IIA in a TRPM7 Kinase-Dependent Manner

(2014) Yin Zhao et al.   MOLECULAR NEUROBIOLOGY

The TRIM-FLMN protein TRIM45 directly interacts with RACK1 and negatively regulates PKC-mediated signaling pathway

(2014) T Sato et al.   ONCOGENE

TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination

(2014) J. Yan et al.   Journal of Molecular Cell Biology

A20 in inflammation and autoimmunity

(2013) Leen Catrysse et al.   TRENDS IN IMMUNOLOGY

Role of Inflammation and Its Mediators in Acute Ischemic Stroke

(2013) Rong Jin et al.   Journal of Cardiovascular Translational Research

TRIM45 negatively regulates NF-κB-mediated transcription and suppresses cell proliferation

(2012) Mio Shibata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tripartite motif 8 (TRIM8) modulates TNF - and IL-1 -triggered NF- B activation by targeting TAK1 for K63-linked polyubiquitination

(2011) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NF-κB and innate immunity in ischemic stroke

(2010) Olivier A. Harari et al.   Annals of the New York Academy of Sciences