Molecular mechanisms of Streptococcus pneumoniae -targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination

The HECT E3 ubiquitin ligase NEDD4 interacts with and ubiquitylates SQSTM1 for inclusion body autophagy

(2017) Qiong Lin et al.   JOURNAL OF CELL SCIENCE

Golgi-Resident GTPase Rab30 Promotes the Biogenesis of Pathogen-Containing Autophagosomes

(2016) Seiichiro Oda et al.   PLoS One

Serotypes, antimicrobial susceptibility, and molecular epidemiology of invasive and non-invasive Streptococcus pneumoniae isolates in paediatric patients after the introduction of 13-valent conjugate vaccine in a nationwide surveillance study conducted in Japan in 2012–2014

(2016) Satoshi Nakano et al.   VACCINE

Pyruvate Oxidase as a Critical Link between Metabolism and Capsule Biosynthesis in Streptococcus pneumoniae

(2016) Haley Echlin et al.   PLoS Pathogens

Autophagy Receptor NDP52 Regulates Pathogen-Containing Autophagosome Maturation

(2015) Pauline Verlhac et al.   Cell Host & Microbe

Streptococcal toxins: role in pathogenesis and disease

(2015) Timothy C. Barnett et al.   CELLULAR MICROBIOLOGY

Unsaturated fatty acids induce non-canonical autophagy

(2015) M. Niso-Santano et al.   EMBO JOURNAL

Che-1-induced inhibition of mTOR pathway enables stress-induced autophagy

(2015) A. Desantis et al.   EMBO JOURNAL

Ubiquitin systems mark pathogen-containing vacuoles as targets for host defense by guanylate binding proteins

(2015) Arun K. Haldar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insufficient Acidification of Autophagosomes Facilitates Group A Streptococcus Survival and Growth in Endothelial Cells

(2015) Shiou-Ling Lu et al.   mBio

Streptococcus pneumoniae induces pyroptosis through the regulation of autophagy in murine microglia

(2015) Ji-Yun Kim et al.   Oncotarget

Establishment of HeLa Cell Mutants Deficient in Sphingolipid-Related Genes Using TALENs

(2014) Toshiyuki Yamaji et al.   PLoS One

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin

(2013) Naonobu Fujita et al.   JOURNAL OF CELL BIOLOGY

Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy

(2013) Yoshinobu Ichimura et al.   MOLECULAR CELL

Streptococcus pneumoniae Invades Endothelial Host Cells via Multiple Pathways and Is Killed in a Lysosome Dependent Manner

(2013) Henrik Gradstedt et al.   PLoS One

The small GTPases Rab9A and Rab23 function at distinct steps in autophagy during Group A Streptococcus infection

(2012) Takashi Nozawa et al.   CELLULAR MICROBIOLOGY

Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes

(2012) N. Ohbayashi et al.   JOURNAL OF CELL SCIENCE

Functional involvement of Rab1A in microtubule-dependent anterograde melanosome transport in melanocytes

(2012) M. Ishida et al.   JOURNAL OF CELL SCIENCE

Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1

(2011) Harald W. Platta et al.   BIOCHEMICAL JOURNAL

A Tecpr1-Dependent Selective Autophagy Pathway Targets Bacterial Pathogens

(2011) Michinaga Ogawa et al.   Cell Host & Microbe

Ammonia-induced autophagy is independent of ULK1/ULK2 kinases

(2011) H. Cheong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab GTPases Regulating Phagosome Maturation Are Differentially Recruited to Mycobacterial Phagosomes

(2011) Shintaro Seto et al.   TRAFFIC

Combinational Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Proteins VAMP8 and Vti1b Mediate Fusion of Antimicrobial and Canonical Autophagosomes with Lysosomes

(2010) Nobumichi Furuta et al.   MOLECULAR BIOLOGY OF THE CELL

Regulation of Rap2A by the Ubiquitin Ligase Nedd4-1 Controls Neurite Development

(2010) Hiroshi Kawabe et al.   NEURON

Application of λ Red recombination system to Vibrio cholerae genetics: Simple methods for inactivation and modification of chromosomal genes

(2009) Shouji Yamamoto et al.   GENE

Listeria monocytogenes ActA-mediated escape from autophagic recognition

(2009) Yuko Yoshikawa et al.   NATURE CELL BIOLOGY

An Initial Step of GAS-Containing Autophagosome-Like Vacuoles Formation Requires Rab7

(2009) Hitomi Yamaguchi et al.   PLoS Pathogens

FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells

(2008) Taichi Hara et al.   JOURNAL OF CELL BIOLOGY

Large Scale Screening for Novel Rab Effectors Reveals Unexpected Broad Rab Binding Specificity

(2008) Mitsunori Fukuda et al.   MOLECULAR & CELLULAR PROTEOMICS

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

The role of Streptococcus pneumoniae virulence factors in host respiratory colonization and disease

(2008) Aras Kadioglu et al.   NATURE REVIEWS MICROBIOLOGY