Annexin-A1 SUMOylation regulates microglial polarization after cerebral ischemia by modulating IKKα stability via selective autophagy

Heart Disease and Stroke Statistics—2019 Update: A Report From the American Heart Association

(2019) Emelia J. Benjamin et al.   CIRCULATION

Global brain inflammation in stroke

(2019) Kaibin Shi et al.   LANCET NEUROLOGY

Inhibiting SUMO1-mediated SUMOylation induces autophagy-mediated cancer cell death and reduces tumour cell invasion via RAC1

(2019) Mar Lorente et al.   JOURNAL OF CELL SCIENCE

Microglia as Dynamic Cellular Mediators of Brain Function

(2019) Elizabeth C. Wright-Jin et al.   TRENDS IN MOLECULAR MEDICINE

The Annexin A1/FPR2 pathway controls the inflammatory response and bacterial dissemination in experimental pneumococcal pneumonia

(2019) Marina Gomes Machado et al.   FASEB JOURNAL

A novel cell-penetrating peptide protects against neuron apoptosis after cerebral ischemia by inhibiting the nuclear translocation of annexin A1

(2018) Xing Li et al.   CELL DEATH AND DIFFERENTIATION

RIPK3/MLKL-Mediated Neuronal Necroptosis Modulates the M1/M2 Polarization of Microglia/Macrophages in the Ischemic Cortex

(2018) Jiping Yang et al.   CEREBRAL CORTEX

Therapeutic Potential of Annexin A1 in Ischemia Reperfusion Injury

(2018) Junaid Ansari et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

DeSUMOylation of MKK7 kinase by the SUMO2/3 protease SENP3 potentiates lipopolysaccharide-induced inflammatory signaling in macrophages

(2018) Yimin Lao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S100A11 protects against neuronal cell apoptosis induced by cerebral ischemia via inhibiting the nuclear translocation of annexin A1

(2018) Qian Xia et al.   Cell Death & Disease

A Critical Role of Autophagy in Regulating Microglia Polarization in Neurodegeneration

(2018) Meng-meng Jin et al.   Frontiers in Aging Neuroscience

Inhibition of AGEs/RAGE/Rho/ROCK pathway suppresses non-specific neuroinflammation by regulating BV2 microglial M1/M2 polarization through the NF-κB pathway

(2017) Jingkao Chen et al.   JOURNAL OF NEUROIMMUNOLOGY

Modulators of microglial activation and polarization after intracerebral haemorrhage

(2017) Xi Lan et al.   Nature Reviews Neurology

The biphasic function of microglia in ischemic stroke

(2017) Yuanyuan Ma et al.   PROGRESS IN NEUROBIOLOGY

Fingolimod Protects Against Ischemic White Matter Damage by Modulating Microglia Toward M2 Polarization via STAT3 Pathway

(2017) Chuan Qin et al.   STROKE

The critical role of SENP1-mediated GATA2 deSUMOylation in promoting endothelial activation in graft arteriosclerosis

(2017) Cong Qiu et al.   Nature Communications

ANGPTL8 negatively regulates NF-κB activation by facilitating selective autophagic degradation of IKKγ

(2017) Yu Zhang et al.   Nature Communications

SUMOylation Promotes Nuclear Import and Stabilization of Polo-like Kinase 1 to Support Its Mitotic Function

(2017) Donghua Wen et al.   Cell Reports

Protein SUMOylation modification and its associations with disease

(2017) Yanfang Yang et al.   Open Biology

The AAA ATPase MDN1 Acts as a SUMO-Targeted Regulator in Mammalian Pre-ribosome Remodeling

(2016) Nithya Raman et al.   MOLECULAR CELL

Nuclear translocation of annexin 1 following oxygen-glucose deprivation–reperfusion induces apoptosis by regulating Bid expression via p53 binding

(2016) Xing Li et al.   Cell Death & Disease

Annexin A1 and the Resolution of Inflammation: Modulation of Neutrophil Recruitment, Apoptosis, and Clearance

(2016) Michelle Amantéa Sugimoto et al.   Journal of Immunology Research

Redox regulation of NF-κB p50 and M1 polarization in microglia

(2014) Thomas Taetzsch et al.   GLIA

Following OGD/R, Annexin 1 Nuclear Translocation and Subsequent Induction of Apoptosis in Neurons Are Assisted by Myosin IIA in a TRPM7 Kinase-Dependent Manner

(2014) Yin Zhao et al.   MOLECULAR NEUROBIOLOGY

Annexin A1 is regulated by domains cross-talk through post-translational phosphorylation and SUMOYlation

(2013) Danielle Caron et al.   CELLULAR SIGNALLING

The complex understanding of Annexin A1 phosphorylation

(2013) Cosimo Walter D'Acunto et al.   CELLULAR SIGNALLING

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

SUMO and Ischemic Tolerance

(2013) Yang-ja Lee et al.   NEUROMOLECULAR MEDICINE

Regulation of Microglia Activity by Glaucocalyxin-A: Attenuation of Lipopolysaccharide-Stimulated Neuroinflammation through NF-κB and p38 MAPK Signaling Pathways

(2013) Byung-Wook Kim et al.   PLoS One

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

SUMO2/3 Conjugation is an Endogenous Neuroprotective Mechanism

(2011) Anna Lena Datwyler et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Characterization of the Interaction of GABARAPL-1 with the LIR Motif of NBR1

(2011) Alexis Rozenknop et al.   JOURNAL OF MOLECULAR BIOLOGY

Ubiquitination and SUMOylation of annexin A1 and helicase activity

(2010) Fusao Hirata et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

SUMOylation and De-SUMOylation: Wrestling with Life's Processes

(2008) Edward T. H. Yeh   JOURNAL OF BIOLOGICAL CHEMISTRY