Influenza-existing drugs and treatment prospects

Antivirals Targeting the Surface Glycoproteins of Influenza Virus: Mechanisms of Action and Resistance

(2021) Yaqin Bai et al.   Viruses-Basel

Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2017–2018

(2020) Emi Takashita et al.   ANTIVIRAL RESEARCH

Influenza

(2020) Dhanya Dharmapalan   INDIAN JOURNAL OF PEDIATRICS

Assessment of efficacy of Oseltamivir-Azithromycin combination therapy in prevention of Influenza-A (H1N1)pdm09 infection complications and rapidity of symptoms relief

(2020) Azfar Athar Ishaqui et al.   Expert Review of Respiratory Medicine

Design of an Efficient Inhibitor for the Influenza A Virus M2 Ion Channel

(2020) Yu. N. Vorobjev   MOLECULAR BIOLOGY

Influenza Pathogenesis: The Effect of Host Factors on Severity of Disease

(2019) Anshu P. Gounder et al.   JOURNAL OF IMMUNOLOGY

Influenza virus polymerase inhibitors in clinical development

(2019) Frederick G. Hayden et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Antivirals targeting the polymerase complex of influenza viruses

(2019) Edin J. Mifsud et al.   ANTIVIRAL RESEARCH

Screening of neuraminidase inhibitory activities of some medicinal plants traditionally used in Lingnan Chinese medicines

(2018) Jiawei Liu et al.   BMC Complementary and Alternative Medicine

Delayed oseltamivir plus sirolimus treatment attenuates H1N1 virus-induced severe lung injury correlated with repressed NLRP3 inflammasome activation and inflammatory cell infiltration

(2018) Xuehong Jia et al.   PLoS Pathogens

Identification of small molecule inhibitors for influenza a virus using in silico and in vitro approaches

(2017) Juliann Nzembi Makau et al.   PLoS One

The mechanisms of sudden-onset type adverse reactions to oseltamivir

(2016) R. Hama et al.   ACTA NEUROLOGICA SCANDINAVICA

Identification and Characterization of Influenza Virus Entry Inhibitors through Dual Myxovirus High-Throughput Screening

(2016) Marco Weisshaar et al.   JOURNAL OF VIROLOGY

Psychiatric Symptoms in a Patient with Influenza A (H1N1) Treated with Oseltamivir (Tamiflu): A Case Report

(2015) Sang Won Jeon et al.   Clinical Psychopharmacology and Neuroscience

Oseltamivir for influenza infection in children: risks and benefits

(2015) Susanna Esposito et al.   Expert Review of Respiratory Medicine

New small-molecule drug design strategies for fighting resistant influenza A

(2015) Zuyuan Shen et al.   Acta Pharmaceutica Sinica B

Nitazoxanide: A first-in-class broad-spectrum antiviral agent

(2014) Jean-François Rossignol   ANTIVIRAL RESEARCH

Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2

(2014) Michael P. Clark et al.   JOURNAL OF MEDICINAL CHEMISTRY

Genesis and pathogenesis of the 1918 pandemic H1N1 influenza A virus

(2014) M. Worobey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-Based Discovery of the Novel Antiviral Properties of Naproxen against the Nucleoprotein of Influenza A Virus

(2013) Nathalie Lejal et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

(2013) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Bioinspired total synthesis of katsumadain A by organocatalytic enantioselective 1,4-conjugate addition

(2013) Yongguang Wang et al.   Beilstein Journal of Organic Chemistry

New treatments for influenza

(2012) Sailen Barik   BMC Medicine

Influenza neuraminidase inhibitors: antiviral action and mechanisms of resistance

(2012) Jennifer L. McKimm-Breschkin   Influenza and Other Respiratory Viruses

Design, Synthesis, and in Vitro Biological Evaluation of 1H-1,2,3-Triazole-4-carboxamide Derivatives as New Anti-influenza A Agents Targeting Virus Nucleoprotein

(2012) Huimin Cheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Influenza Virus-Mediated Membrane Fusion: Determinants of Hemagglutinin Fusogenic Activity and Experimental Approaches for Assessing Virus Fusion

(2012) Brian S. Hamilton et al.   Viruses-Basel

Mechanism of Inhibition of Enveloped Virus Membrane Fusion by the Antiviral Drug Arbidol

(2011) Elodie Teissier et al.   PLoS One

Laninamivir Prodrug CS-8958, a Long-Acting Neuraminidase Inhibitor, Shows Superior Anti-Influenza Virus Activity after a Single Administration

(2010) S. Kubo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efficacy and Safety of Intravenous Peramivir for Treatment of Seasonal Influenza Virus Infection

(2010) S. Kohno et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Long-Acting Neuraminidase Inhibitor Laninamivir Octanoate (CS-8958) versus Oseltamivir as Treatment for Children with Influenza Virus Infection

(2010) N. Sugaya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Long‐Acting Neuraminidase Inhibitor Laninamivir Octanoate versus Oseltamivir for Treatment of Influenza: A Double‐Blind, Randomized, Noninferiority Clinical Trial

(2010) Akira Watanabe et al.   CLINICAL INFECTIOUS DISEASES

Drugs in Development for Influenza

(2010) David A. Boltz et al.   DRUGS

Identification of influenza A nucleoprotein as an antiviral target

(2010) Richard Y Kao et al.   NATURE BIOTECHNOLOGY

CS-8958, a Prodrug of the Novel Neuraminidase Inhibitor R-125489, Demonstrates a Favorable Long-Retention Profile in the Mouse Respiratory Tract

(2009) K. Koyama et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice

(2009) D. F. Smee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synthesis and anti-viral activity of azolo-adamantanes against influenza A virus

(2009) Vladimir V. Zarubaev et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Oseltamivir and Abnormal Behaviors

(2009) Takashi Yorifuji et al.   EPIDEMIOLOGY

Curcumin inhibits influenza virus infection and haemagglutination activity

(2009) Da-Yuan Chen et al.   FOOD CHEMISTRY

High prevalence of amantadine resistance among circulating European porcine influenza A viruses

(2009) A. Krumbholz et al.   JOURNAL OF GENERAL VIROLOGY

Zanamivir-Resistant Influenza Viruses with a Novel Neuraminidase Mutation

(2009) A. C. Hurt et al.   JOURNAL OF VIROLOGY

Possible harms of oseltamivir—a call for urgent action

(2009) Tom Jefferson et al.   LANCET

Use of Ribavirin to Treat Influenza

(2009) Kirk M. Chan-Tack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Elderberry flavonoids bind to and prevent H1N1 infection in vitro

(2009) Bill Roschek et al.   PHYTOCHEMISTRY

Dating the emergence of pandemic influenza viruses

(2009) Gavin J. D. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of drug inhibition and drug resistance of influenza A M2 channel

(2009) R. M. Pielak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treatment of influenza A (H1N1) virus infections in mice and ferrets with cyanovirin-N

(2008) D SMEE et al.   ANTIVIRAL RESEARCH

Developing New Antiviral Agents for Influenza Treatment: What Does the Future Hold?

(2008) Frederick Hayden   CLINICAL INFECTIOUS DISEASES

Oseltamivir (Tamiflu®) increases dopamine levels in the rat medial prefrontal cortex

(2008) Tatsuki Yoshino et al.   NEUROSCIENCE LETTERS