NLRP3 inflammasome of microglia promotes A1 astrocyte transformation, neo-neuron decline and cognition impairment in endotoxemia

16-Substituted steroids alleviate LPS-induced neurodegenerative disorders in rats

(2021) Ranjit Singh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

A Novel Treatment Strategy by Natural Products in NLRP3 Inflammasome-Mediated Neuroinflammation in Alzheimer’s and Parkinson’s Disease

(2021) Jun Ho Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Involvement and relationship of bacterial lipopolysaccharides and cyclooxygenases levels in Alzheimer's disease and mild cognitive impairment patients

(2021) G. Andreadou Eleni et al.   JOURNAL OF NEUROIMMUNOLOGY

A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage

(2021) Suling Huang et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

CXCR5 down-regulation alleviates cognitive dysfunction in a mouse model of sepsis-associated encephalopathy: potential role of microglial autophagy and the p38MAPK/NF-κB/STAT3 signaling pathway

(2021) Yanan Shen et al.   Journal of Neuroinflammation

NLRP3 Inflammasome Contributes to Host Defense Against Talaromyces marneffei Infection

(2021) Haiyan Ma et al.   Frontiers in Immunology

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Children and Adolescents

(2020) Riccardo Castagnoli et al.   JAMA Pediatrics

Alzheimer’s disease: new concepts on the role of autoimmunity and of NLRP3 inflammasome in the pathogenesis of the disease

(2020) Cinzia Severini et al.   Current Neuropharmacology

Baicalein Attenuates Neuroinflammation by Inhibiting NLRP3/caspase-1/GSDMD Pathway in MPTP Induced Mice Model of Parkinson’s Disease

(2020) Wenjuan Rui et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

New mechanism of neuroinflammation in Alzheimer's disease: The activation of NLRP3 inflammasome mediated by gut microbiota

(2020) Heping Shen et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The involvement of NLRP3 inflammasome in the treatment of Alzheimer’s disease

(2020) Ya-Shuo Feng et al.   AGEING RESEARCH REVIEWS

Silencing IFNγ inhibits A1 astrocytes and attenuates neurogenesis decline and cognitive impairment in endotoxemia

(2020) Yanyan Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The emerging roles of NOD-like receptors in antiviral innate immune signaling pathways

(2020) Chunfu Zheng   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Activation of Both TLR and NOD Signaling Confers Host Innate Immunity-Mediated Protection Against Microbial Infection

(2019) Huiting Zhou et al.   Frontiers in Immunology

Small molecule-driven NLRP3 inflammation inhibition via interplay between ubiquitination and autophagy: implications for Parkinson disease

(2019) Xiaojuan Han et al.   Autophagy

Global burden of cancer attributable to infections in 2018: a worldwide incidence analysis

(2019) Catherine de Martel et al.   Lancet Global Health

Long-Term Cognitive Outcomes After Sepsis: a Translational Systematic Review

(2018) Tatiana Barichello et al.   MOLECULAR NEUROBIOLOGY

Astrocytes decrease adult neurogenesis during virus-induced memory dysfunction via IL-1

(2018) Charise Garber et al.   NATURE IMMUNOLOGY

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

(2018) Seung Pil Yun et al.   NATURE MEDICINE

Cognitive deficits and educational loss in children with schistosome infection—A systematic review and meta-analysis

(2018) Amara E. Ezeamama et al.   PLoS Neglected Tropical Diseases

6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment partially via suppressing astrocyte overactivation

(2018) Feng Zhang et al.   BIOMEDICINE & PHARMACOTHERAPY

NLRP3/Caspase-1 Pathway-Induced Pyroptosis Mediated Cognitive Deficits in a Mouse Model of Sepsis-Associated Encephalopathy

(2018) Qun Fu et al.   INFLAMMATION

Correlative Light-Electron Microscopy detects lipopolysaccharide and its association with fibrin fibres in Parkinson’s Disease, Alzheimer’s Disease and Type 2 Diabetes Mellitus

(2018) Greta M. de Waal et al.   Scientific Reports

Inhibiting RIP1 Improves Chronic Stress-Induced Cognitive Impairments in D-Galactose-Induced Aging Mice

(2018) Wenxiang Qing et al.   Frontiers in Behavioral Neuroscience

Potentially modifiable factors contributing to sepsis-associated encephalopathy

(2017) Romain Sonneville et al.   INTENSIVE CARE MEDICINE

NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation

(2017) Nan Song et al.   MOLECULAR CELL

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

The Changing Epidemiology and Definitions of Sepsis

(2016) Jordan A. Kempker et al.   CLINICS IN CHEST MEDICINE

Stress Disorders Following Prolonged Critical Illness in Survivors of Severe Sepsis

(2015) Gloria-Beatrice Wintermann et al.   CRITICAL CARE MEDICINE

Cellular stress response and innate immune signaling: integrating pathways in host defense and inflammation

(2013) Sujatha Muralidharan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Long-Term Cognitive Impairment after Critical Illness

(2013) P.P. Pandharipande et al.   NEW ENGLAND JOURNAL OF MEDICINE

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE