A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A new mechanism of obeticholic acid on NASH treatment by inhibiting NLRP3 inflammasome activation in macrophage
Authors
Keywords
Macrophage, NLRP3 inflammasome, Hepatic lipid accumulation, NASH, FXR
Journal
METABOLISM-CLINICAL AND EXPERIMENTAL
Volume 120, Issue -, Pages 154797
Publisher
Elsevier BV
Online
2021-05-10
DOI
10.1016/j.metabol.2021.154797
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mitochondrial dynamics and nonalcoholic fatty liver disease (NAFLD): new perspectives for a fairy-tale ending?
- (2021) Miriam Longo et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Revealing the role of peroxisome proliferator-activated receptor β/δ in nonalcoholic fatty liver disease
- (2020) Mohammad Zarei et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Macrophage p38α promotes nutritional steatohepatitis through M1 polarization
- (2019) Xiang Zhang et al. JOURNAL OF HEPATOLOGY
- Past, present and future perspectives in nonalcoholic fatty liver disease
- (2019) Arun J. Sanyal Nature Reviews Gastroenterology & Hepatology
- New drugs for NAFLD: lessons from basic models to the clinic
- (2019) Katharina C. Reimer et al. Hepatology International
- Impact of obeticholic acid on the lipoprotein profile in patients with non-alcoholic steatohepatitis
- (2019) Mohammad Shadab Siddiqui et al. JOURNAL OF HEPATOLOGY
- Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial
- (2019) Zobair M Younossi et al. LANCET
- Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
- (2018) David Højland Ipsen et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Impact of steatosis and inflammation definitions on the performance of NASH tests
- (2018) Thierry Poynard et al. EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY
- Triggering and resolution of inflammation in NASH
- (2018) Susanne Schuster et al. Nature Reviews Gastroenterology & Hepatology
- Metabolic and hepatic effects of liraglutide, obeticholic acid and elafibranor in diet-induced obese mouse models of biopsy-confirmed nonalcoholic steatohepatitis
- (2018) Kirstine S Tølbøl et al. WORLD JOURNAL OF GASTROENTEROLOGY
- NLRP3 Deletion Inhibits the Non-alcoholic Steatohepatitis Development and Inflammation in Kupffer Cells Induced by Palmitic Acid
- (2017) Can Cai et al. INFLAMMATION
- Targeting hepatic macrophages to treat liver diseases
- (2017) Frank Tacke JOURNAL OF HEPATOLOGY
- NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
- (2017) Auvro R. Mridha et al. JOURNAL OF HEPATOLOGY
- Modelling immune–microbe interaction in 3D intestinal culture
- (2017) Hugh Thomas Nature Reviews Gastroenterology & Hepatology
- Role of NLRP3 Inflammasome in the Progression of NAFLD to NASH
- (2016) Xingyong Wan et al. Canadian Journal of Gastroenterology and Hepatology
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
- (2015) Rebecca C Coll et al. NATURE MEDICINE
- Inflammasome activation and function in liver disease
- (2015) Gyongyi Szabo et al. Nature Reviews Gastroenterology & Hepatology
- Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis
- (2014) Timea Csak et al. LIVER INTERNATIONAL
- IL-1 Signaling in Obesity-Induced Hepatic Lipogenesis and Steatosis
- (2014) Kimberly A. Negrin et al. PLoS One
- Establishment of a General NAFLD Scoring System for Rodent Models and Comparison to Human Liver Pathology
- (2014) Wen Liang et al. PLoS One
- A high-fat diet and multiple administration of carbon tetrachloride induces liver injury and pathological features associated with non-alcoholic steatohepatitis in mice
- (2013) Norihiro Kubota et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice
- (2013) Alexander Wree et al. HEPATOLOGY
- Caspase-1 as a Central Regulator of High Fat Diet-Induced Non-Alcoholic Steatohepatitis
- (2013) Laura J. Dixon et al. PLoS One
- Inflammasomes in liver diseases
- (2012) Gyongyi Szabo et al. JOURNAL OF HEPATOLOGY
- Arctigenin, a natural compound, activates AMP-activated protein kinase via inhibition of mitochondria complex I and ameliorates metabolic disorders in ob/ob mice
- (2011) S.-L. Huang et al. DIABETOLOGIA
- SREBP-2: A link between insulin resistance, hepatic cholesterol, and inflammation in NASH
- (2011) Derrick M Van Rooyen et al. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY
- The interaction of hepatic lipid and glucose metabolism in liver diseases
- (2011) Lars P. Bechmann et al. JOURNAL OF HEPATOLOGY
- Toll-Like Receptor 9 Promotes Steatohepatitis by Induction of Interleukin-1β in Mice
- (2010) Kouichi Miura et al. GASTROENTEROLOGY
- Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings
- (2010) Elizabeth M. Brunt et al. HEPATOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now