Bifunctional Fusion Membrane‐Based Hydrogel Enhances Antitumor Potency of Autologous Cancer Vaccines by Activating Dendritic Cells

A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells

(2021) Sijin Cheng et al.   CELL

Accuracy of Using a Patient-Derived Tumor Organoid Culture Model to Predict the Response to Chemotherapy Regimens In Stage IV Colorectal Cancer

(2021) Ting Wang et al.   DISEASES OF THE COLON & RECTUM

Ultrasound-Mediated Remotely Controlled Nanovaccine Delivery for Tumor Vaccination and Individualized Cancer Immunotherapy

(2021) Zhouqi Meng et al.   NANO LETTERS

Bacteria‐Based Cancer Immunotherapy

(2021) Xuehui Huang et al.   Advanced Science

Soluble and Microparticle‐Based Delivery of TLR4 and TLR9 Agonists Differentially Modulate 3D Chemotaxis of Bone Marrow‐Derived Dendritic Cells

(2021) Alexandra Atalis et al.   Advanced Healthcare Materials

Immunotherapy and Prevention of Cancer by Nanovaccines Loaded with Whole‐Cell Components of Tumor Tissues or Cells

(2021) Lin Ma et al.   ADVANCED MATERIALS

Bacterial cytoplasmic membranes synergistically enhance the antitumor activity of autologous cancer vaccines

(2021) Long Chen et al.   Science Translational Medicine

Hybrid Vesicles Based on Autologous Tumor Cell Membrane and Bacterial Outer Membrane To Enhance Innate Immune Response and Personalized Tumor Immunotherapy

(2021) Mei-Zhen Zou et al.   NANO LETTERS

Single-Cell Transcriptomic Analysis Reveals a Tumor-Reactive T Cell Signature Associated With Clinical Outcome and Immunotherapy Response In Melanoma

(2021) Min Yan et al.   Frontiers in Immunology

Fibrin gel enhances the antitumor effects of chimeric antigen receptor T cells in glioblastoma

(2021) Edikan A. Ogunnaike et al.   Science Advances

Localized cocktail chemoimmunotherapy after in situ gelation to trigger robust systemic antitumor immune responses

(2020) Yu Chao et al.   Science Advances

Supramolecular prodrug hydrogelator as an immune booster for checkpoint blocker–based immunotherapy

(2020) Feihu Wang et al.   Science Advances

Autologous tumor cell vaccine induces antitumor T cell immune responses in patients with mantle cell lymphoma: A phase I/II trial

(2020) Matthew J. Frank et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumour sensitization via the extended intratumoural release of a STING agonist and camptothecin from a self-assembled hydrogel

(2020) Feihu Wang et al.   Nature Biomedical Engineering

Local and Targeted Delivery of Immune Checkpoint Blockade Therapeutics

(2020) Xiao Han et al.   ACCOUNTS OF CHEMICAL RESEARCH

Coexpression of IL7 and CCL21 Increases Efficacy of CAR-T Cells in Solid Tumors without Requiring Preconditioned Lymphodepletion

(2020) Hong Luo et al.   CLINICAL CANCER RESEARCH

Proton-driven transformable nanovaccine for cancer immunotherapy

(2020) Ningqiang Gong et al.   Nature Nanotechnology

Blockade of immune checkpoints in lymph nodes through locoregional delivery augments cancer immunotherapy

(2020) David M. Francis et al.   Science Translational Medicine

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma

(2019) Timothy F. Cloughesy et al.   NATURE MEDICINE

Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors

(2019) Denarda Dangaj et al.   CANCER CELL

Injectable Polymer–Nanoparticle Hydrogels for Local Immune Cell Recruitment

(2019) Owen S. Fenton et al.   BIOMACROMOLECULES

Cancer Cell Membrane-Coated Adjuvant Nanoparticles with Mannose Modification for Effective Anticancer Vaccination

(2018) Rong Yang et al.   ACS Nano

Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

(2018) Elham Azizi et al.   CELL

Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer

(2018) Janos L. Tanyi et al.   Science Translational Medicine

Randomized phase II trial of autologous dendritic cell vaccines versus autologous tumor cell vaccines in metastatic melanoma: 5-year follow up and additional analyses

(2018) Robert O. Dillman et al.   Journal for ImmunoTherapy of Cancer

PEGylated tumor cell membrane vesicles as a new vaccine platform for cancer immunotherapy

(2018) Lukasz J. Ochyl et al.   BIOMATERIALS

In Situ Fabrication of Intelligent Photothermal Indocyanine Green–Alginate Hydrogel for Localized Tumor Ablation

(2018) Haiyan Pan et al.   ACS Applied Materials & Interfaces

Organoid Modeling of the Tumor Immune Microenvironment

(2018) James T. Neal et al.   CELL

Interleukin-15 and cisplatin co-encapsulated thermosensitive polypeptide hydrogels for combined immuno-chemotherapy

(2017) Xilong Wu et al.   JOURNAL OF CONTROLLED RELEASE

Smart Ferrofluid with Quick Gel Transformation in Tumors for MRI-Guided Local Magnetic Thermochemotherapy

(2016) Koichiro Hayashi et al.   ADVANCED FUNCTIONAL MATERIALS

Cancer-Cell-Biomimetic Nanoparticles for Targeted Therapy of Homotypic Tumors

(2016) Huiping Sun et al.   ADVANCED MATERIALS

Chitosan thermogels for local expansion and delivery of tumor-specific T lymphocytes towards enhanced cancer immunotherapies

(2016) Anne Monette et al.   BIOMATERIALS

Microbiome and Anticancer Immunosurveillance

(2016) Laurence Zitvogel et al.   CELL

Injectable hydrogel-based drug delivery systems for local cancer therapy

(2016) Mohammad Norouzi et al.   DRUG DISCOVERY TODAY

Mycobacterium phleicell wall-nucleic acid complex in the treatment of nonmuscle invasive bladder cancer unresponsive to bacillus Calmette-Guerin

(2016) Alvaro Morales et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

The microbiome and innate immunity

(2016) Christoph A. Thaiss et al.   NATURE

Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens

(2016) Latha B. Pathangey et al.   Oncotarget

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

(2015) Sylvia F. Boj et al.   CELL

Alginate gel particles–A review of production techniques and physical properties

(2015) Su Hung Ching et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Injectable cryogel-based whole-cell cancer vaccines

(2015) Sidi A. Bencherif et al.   Nature Communications

Hydrogel dual delivered celecoxib and anti-PD-1 synergistically improve antitumor immunity

(2015) Yongkui Li et al.   OncoImmunology

Cancer Cell Membrane-Coated Nanoparticles for Anticancer Vaccination and Drug Delivery

(2014) Ronnie H. Fang et al.   NANO LETTERS

Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy

(2012) L. van de Laar et al.   BLOOD

Mucosal Immunology and Probiotics

(2012) Maria Luisa Dongarrà et al.   CURRENT ALLERGY AND ASTHMA REPORTS

Mechanisms of Oxidative Protein Folding in the Bacterial Cell Envelope

(2010) Hiroshi Kadokura et al.   ANTIOXIDANTS & REDOX SIGNALING

Injectable dendritic cell-carrying alginate gels for immunization and immunotherapy

(2008) Yuki Hori et al.   BIOMATERIALS

Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation

(2008) Martijn S. Bijker et al.   EUROPEAN JOURNAL OF IMMUNOLOGY