Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy

Deacetylase Activity Is Required for STAT5-Dependent GM-CSF Functional Activity in Macrophages and Differentiation to Dendritic Cells

(2014) Carlos Sebastián et al.   JOURNAL OF IMMUNOLOGY

Granulocyte–macrophage colony-stimulating factor increases the proportion of circulating dendritic cells after autologous but not after allogeneic hematopoietic stem cell transplantation

(2011) Erika Adriana Eksioglu et al.   CYTOTHERAPY

Myeloid neoplasm-related gene abnormalities differentially affect dendritic cell differentiation from murine hematopoietic stem/progenitor cells

(2011) Jiro Fujita et al.   IMMUNOLOGY LETTERS

Defective IL-10 signaling in hyper-IgE syndrome results in impaired generation of tolerogenic dendritic cells and induced regulatory T cells

(2011) Masako Saito et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tight Control of STAT5 Activity Determines Human CD34-Derived Interstitial Dendritic Cell and Langerhans Cell Development

(2011) L. van de Laar et al.   JOURNAL OF IMMUNOLOGY

Differentiation of Inflammatory Dendritic Cells Is Mediated by NF- B1-Dependent GM-CSF Production in CD4 T Cells

(2011) I. K. Campbell et al.   JOURNAL OF IMMUNOLOGY

IRF8Mutations and Human Dendritic-Cell Immunodeficiency

(2011) Sophie Hambleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

I B kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia

(2010) N. Chapuis et al.   BLOOD

Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells

(2010) C. Ghirelli et al.   BLOOD

Targeting Stat3 in the Myeloid Compartment Drastically Improves the In vivo Antitumor Functions of Adoptively Transferred T Cells

(2010) A. Herrmann et al.   CANCER RESEARCH

GM-CSF-armed, replication-competent viruses for cancer

(2010) James M. Burke   CYTOKINE & GROWTH FACTOR REVIEWS

MAPK3 deficiency drives autoimmunity via DC arming

(2010) Ivo Bendix et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mammalian Target of Rapamycin Controls Dendritic Cell Development Downstream of Flt3 Ligand Signaling

(2010) Taheri Sathaliyawala et al.   IMMUNITY

Harnessing human dendritic cell subsets for medicine

(2010) Hideki Ueno et al.   IMMUNOLOGICAL REVIEWS

Surprising new roles for PU.1 in the adaptive immune response

(2010) Sebastian Carotta et al.   IMMUNOLOGICAL REVIEWS

Programmed cell death of dendritic cells in immune regulation

(2010) Min Chen et al.   IMMUNOLOGICAL REVIEWS

Origin and development of dendritic cells

(2010) Kang Liu et al.   IMMUNOLOGICAL REVIEWS

Enhancement of DC vaccine potency by activating the PI3K/AKT pathway with a small interfering RNA targeting PTEN

(2010) Jin Hee Kim et al.   IMMUNOLOGY LETTERS

Human CD34-Derived Myeloid Dendritic Cell Development Requires Intact Phosphatidylinositol 3-Kinase-Protein Kinase B-Mammalian Target of Rapamycin Signaling

(2010) L. van de Laar et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cell (DC)-Specific Targeting Reveals Stat3 as a Negative Regulator of DC Function

(2010) Jessica A. Melillo et al.   JOURNAL OF IMMUNOLOGY

A Nonredundant Role for Canonical NF- B in Human Myeloid Dendritic Cell Development and Function

(2010) L. van de Laar et al.   JOURNAL OF IMMUNOLOGY

A Novel TNF Receptor-Associated Factor 6 Binding Domain Mediates NF- B Signaling by the Common Cytokine Receptor   Subunit

(2010) M. B. Meads et al.   JOURNAL OF IMMUNOLOGY

A Versatile Role of Mammalian Target of Rapamycin in Human Dendritic Cell Function and Differentiation

(2010) M. Haidinger et al.   JOURNAL OF IMMUNOLOGY

SHIP Is Required for Dendritic Cell Maturation

(2010) F. Antignano et al.   JOURNAL OF IMMUNOLOGY

Loss of Jak2 Selectively Suppresses DC-Mediated Innate Immune Response and Protects Mice from Lethal Dose of LPS-Induced Septic Shock

(2010) Jixin Zhong et al.   PLoS One

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

The concerted action of GM-CSF and Flt3-ligand on in vivo dendritic cell homeostasis

(2009) D. Kingston et al.   BLOOD

Dendritic cell homeostasis

(2009) M. Merad et al.   BLOOD

The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease

(2009) T. R. Hercus et al.   BLOOD

Targeted NF-κB inhibition of asthmatic serum-mediated human monocyte-derived dendritic cell differentiation in a transendothelial trafficking model

(2009) Xiao-Yan Gu et al.   CELLULAR IMMUNOLOGY

Tumor-mediated down-regulation of MHC class II in DC development is attributable to the epigenetic control of the CIITA type I promoter

(2009) Young-Eun Choi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Intestinal Lamina Propria Dendritic Cell Subsets Have Different Origin and Functions

(2009) Chen Varol et al.   IMMUNITY

Origin of the Lamina Propria Dendritic Cell Network

(2009) Milena Bogunovic et al.   IMMUNITY

NF- B p50 Regulates C/EBP  Expression and Inflammatory Cytokine-Induced Neutrophil Production

(2009) D. Wang et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Negative Regulation of Dendritic Cells through Acetylation of the Nonhistone Protein STAT-3

(2009) Yaping Sun et al.   JOURNAL OF IMMUNOLOGY

MAPK signaling pathways in the regulation of hematopoiesis

(2009) Christian R. Geest et al.   JOURNAL OF LEUKOCYTE BIOLOGY

STAT3- and STAT5-dependent pathways competitively regulate the pan-differentiation of CD34pos cells into tumor-competent dendritic cells

(2008) P. A. Cohen et al.   BLOOD

The Signal Transducer STAT5 Inhibits Plasmacytoid Dendritic Cell Development by Suppressing Transcription Factor IRF8

(2008) Eiji Esashi et al.   IMMUNITY

Dendritic cells transduced with lentiviral-mediated RelB-specific ShRNAs inhibit the development of experimental autoimmune myasthenia gravis

(2008) Yong Zhang et al.   MOLECULAR IMMUNOLOGY

The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues

(2008) Claudia Waskow et al.   NATURE IMMUNOLOGY

PI3K/Akt: getting it right matters

(2008) T F Franke   ONCOGENE