Targeted Manipulation of Cellular RNA m6A Methylation at the Single-Base Level

m 6 A RNA methylation: from mechanisms to therapeutic potential

(2021) P Cody He et al.   EMBO JOURNAL

A Mutation‐Based Method for Pinpointing a DNA N 6 ‐Methyladenine Methyltransferase Modification Site at Single Base Resolution

(2021) Mohan Cheng et al.   CHEMBIOCHEM

Functional Features and Current Applications of the RNA‐Targeting Type VI CRISPR‐Cas Systems

(2021) Vanja Perčulija et al.   Advanced Science

Mapping messenger RNA methylations at single base resolution

(2021) Jie Cao et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Programmable technologies to manipulate gene expression at the RNA level

(2021) Huachun Liu et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The challenge and prospect of mRNA therapeutics landscape

(2020) Yuhua Weng et al.   BIOTECHNOLOGY ADVANCES

A metabolic labeling method detects m6A transcriptome-wide at single base resolution

(2020) Xiao Shu et al.   Nature Chemical Biology

Targeted mRNA demethylation using an engineered dCas13b-ALKBH5 fusion protein

(2020) Jiexin Li et al.   NUCLEIC ACIDS RESEARCH

m6A Editing: New Tool to Improve Crop Quality?

(2020) Hong-xiang Zheng et al.   TRENDS IN PLANT SCIENCE

Programmable m6A modification of cellular RNAs with a Cas13-directed methyltransferase

(2020) Christopher Wilson et al.   NATURE BIOTECHNOLOGY

Photoactivatable RNA N 6 ‐Methyladenosine Editing with CRISPR‐Cas13

(2020) Jie Zhao et al.   Small

TRADES: Targeted RNA Demethylation by SunTag System

(2020) Jing Mo et al.   Advanced Science

Structural insights into FTO’s catalytic mechanism for the demethylation of multiple RNA substrates

(2019) Xiao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Advances in CRISPR-Cas systems for RNA targeting, tracking and editing

(2019) Fei Wang et al.   BIOTECHNOLOGY ADVANCES

Where, When, and How: Context-Dependent Functions of RNA Methylation Writers, Readers, and Erasers

(2019) Hailing Shi et al.   MOLECULAR CELL

Sequence-specific m6A demethylation in RNA by FTO fused to RCas9

(2019) Kristina Rau et al.   RNA

Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates

(2019) Xiao-Min Liu et al.   Nature Chemical Biology

Reading, writing and erasing mRNA methylation

(2019) Sara Zaccara et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Functions, mechanisms and regulation of Pumilio/Puf family RNA binding proteins: a comprehensive review

(2019) M. J. Nishanth et al.   MOLECULAR BIOLOGY REPORTS

Molecular Mechanisms of RNA Targeting by Cas13-containing Type VI CRISPR–Cas Systems

(2018) Mitchell R. O'Connell   JOURNAL OF MOLECULAR BIOLOGY

mRNA circularization by METTL3–eIF3h enhances translation and promotes oncogenesis

(2018) Junho Choe et al.   NATURE

CRISPR-Cas guides the future of genetic engineering

(2018) Gavin J. Knott et al.   SCIENCE

Class 2 CRISPR/Cas: an expanding biotechnology toolbox for and beyond genome editing

(2018) Yuyi Tang et al.   Cell and Bioscience

N6-Allyladenosine: A New Small Molecule for RNA Labeling Identified by Mutation Assay

(2017) Xiao Shu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RNA m6A methylation regulates the ultraviolet-induced DNA damage response

(2017) Yang Xiang et al.   NATURE

Promoter-bound METTL3 maintains myeloid leukaemia by m6A-dependent translation control

(2017) Isaia Barbieri et al.   NATURE

RNA targeting with CRISPR–Cas13

(2017) Omar O. Abudayyeh et al.   NATURE

RNA fate determination through cotranscriptional adenosine methylation and microprocessor binding

(2017) Philip Knuckles et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3′-end processing

(2017) Marek Bartosovic et al.   NUCLEIC ACIDS RESEARCH

ALKBH5-dependent m6A demethylation controls splicing and stability of long 3′-UTR mRNAs in male germ cells

(2017) Chong Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA editing with CRISPR-Cas13

(2017) David B. T. Cox et al.   SCIENCE

RNA fate determination through cotranscriptional adenosine methylation and microprocessor binding

(2017) Philip Knuckles et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

YTHDC1 mediates nuclear export of N6-methyladenosine methylated mRNAs

(2017) Ian A Roundtree et al.   eLife

Programmable RNA Tracking in Live Cells with CRISPR/Cas9

(2016) David A. Nelles et al.   CELL

Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases

(2016) Ping Wang et al.   MOLECULAR CELL

The m 6 A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells

(2016) Shuibin Lin et al.   MOLECULAR CELL

Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2016) Xiang Wang et al.   NATURE

C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector

(2016) Omar O. Abudayyeh et al.   SCIENCE

A novel RNA-guided RNA-targeting CRISPR tool

(2016) Dandan Zhang et al.   Science China-Life Sciences

Structural insights into the molecular mechanism of the m6A writer complex

(2016) Paweł Śledź et al.   eLife

Structures of Human ALKBH5 Demethylase Reveal a Unique Binding Mode for Specific Single-strandedN6-Methyladenosine RNA Demethylation

(2014) Chao Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structures of the Human RNA Demethylase Alkbh5 Reveal Basis for Substrate Recognition

(2014) Chong Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Programmable RNA recognition and cleavage by CRISPR/Cas9

(2014) Mitchell R. O’Connell et al.   NATURE

The new frontier of genome engineering with CRISPR-Cas9

(2014) J. A. Doudna et al.   SCIENCE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Transcriptome-wide mapping of N6-methyladenosine by m6A-seq based on immunocapturing and massively parallel sequencing

(2013) Dan Dominissini et al.   Nature Protocols

ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility

(2012) Guanqun Zheng et al.   MOLECULAR CELL

N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO

(2011) Guifang Jia et al.   Nature Chemical Biology

Designer RNA-binding proteins: New tools for manipulating the transcriptome

(2011) Aleksandra Filipovska et al.   RNA Biology