RNA fate determination through cotranscriptional adenosine methylation and microprocessor binding

Multipotency of Adult Hippocampal NSCs In Vivo Is Restricted by Drosha/NFIB

(2016) Chiara Rolando et al.   Cell Stem Cell

Reversible methylation of m6Am in the 5′ cap controls mRNA stability

(2016) Jan Mauer et al.   NATURE

Post-transcriptional gene regulation by mRNA modifications

(2016) Boxuan Simen Zhao et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation

(2016) Lars Schomacher et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Alternative splicing affects the subcellular localization of Drosha

(2016) Steffen Link et al.   NUCLEIC ACIDS RESEARCH

The Ensembl gene annotation system

(2016) Bronwen L. Aken et al.   Database-The Journal of Biological Databases and Curation

Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation

(2016) Lars Schomacher et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events

(2015) Claudio R. Alarcón et al.   CELL

A majority of m6A residues are in the last exons, allowing the potential for 3′ UTR regulation

(2015) Shengdong Ke et al.   GENES & DEVELOPMENT

DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs

(2015) Sara Macias et al.   MOLECULAR CELL

N6-methyladenosine marks primary microRNAs for processing

(2015) Claudio R. Alarcón et al.   NATURE

Dynamic m6A mRNA methylation directs translational control of heat shock response

(2015) Jun Zhou et al.   NATURE

Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis

(2015) Timothy M Johanson et al.   NATURE IMMUNOLOGY

m6A mRNA methylation facilitates resolution of naïve pluripotency toward differentiation

(2015) Shay Geula et al.   SCIENCE

Single-Step Generation of Conditional Knockout Mouse Embryonic Stem Cells

(2015) Matyas Flemr et al.   Cell Reports

Dicer and Hsp104 Function in a Negative Feedback Loop to Confer Robustness to Environmental Stress

(2015) Daniele Oberti et al.   Cell Reports

QuasR: quantification and annotation of short reads in R

(2014) Dimos Gaidatzis et al.   BIOINFORMATICS

m6A RNA Modification Controls Cell Fate Transition in Mammalian Embryonic Stem Cells

(2014) Pedro J. Batista et al.   Cell Stem Cell

The evolution of lncRNA repertoires and expression patterns in tetrapods

(2014) Anamaria Necsulea et al.   NATURE

The evolutionary journey of Argonaute proteins

(2014) Daan C Swarts et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Absolute and relative quantification of RNA modifications via biosynthetic isotopomers

(2014) Stefanie Kellner et al.   NUCLEIC ACIDS RESEARCH

deepTools: a flexible platform for exploring deep-sequencing data

(2014) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

The UCSC Genome Browser database: 2015 update

(2014) Kate R. Rosenbloom et al.   NUCLEIC ACIDS RESEARCH

Hsp70 in cancer: back to the future

(2014) M Y Sherman et al.   ONCOGENE

A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

The fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry

(2013) Martin E Hess et al.   NATURE NEUROSCIENCE

RNA interference in the nucleus: roles for small RNAs in transcription, epigenetics and beyond

(2013) Stephane E. Castel et al.   NATURE REVIEWS GENETICS

The Microprocessor controls the activity of mammalian retrotransposons

(2013) Sara R Heras et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Drosha Regulates Gene Expression Independently of RNA Cleavage Function

(2013) Natalia Gromak et al.   Cell Reports

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

Transcription-associated quality control of mRNP

(2012) Manfred Schmid et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons

(2012) Kate D. Meyer et al.   CELL

RNAi in fission yeast finds new targets and new ways of targeting at the nuclear periphery

(2012) D. Holoch et al.   GENES & DEVELOPMENT

RNAi keeps Atf1-bound stress response genes in check at nuclear pores

(2012) K. J. Woolcock et al.   GENES & DEVELOPMENT

HP1Swi6 Mediates the Recognition and Destruction of Heterochromatic RNA Transcripts

(2012) Claudia Keller et al.   MOLECULAR CELL

Drosha regulates neurogenesis by controlling Neurogenin 2 expression independent of microRNAs

(2012) Philip Knuckles et al.   NATURE NEUROSCIENCE

DGCR8 HITS-CLIP reveals novel functions for the Microprocessor

(2012) Sara Macias et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

GC-Content Normalization for RNA-Seq Data

(2011) Davide Risso et al.   BMC BIOINFORMATICS

Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila

(2011) Filippo M. Cernilogar et al.   NATURE

Targeting heat shock proteins in cancer

(2010) Gaëtan Jego et al.   CANCER LETTERS

Nuclear Retention of Fission Yeast Dicer Is a Prerequisite for RNAi-Mediated Heterochromatin Assembly

(2010) Stephan Emmerth et al.   DEVELOPMENTAL CELL

Ab initio reconstruction of cell type–specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs

(2010) Mitchell Guttman et al.   NATURE BIOTECHNOLOGY

Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe

(2010) Katrina J Woolcock et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nuclear Stress Bodies

(2010) G. Biamonti et al.   Cold Spring Harbor Perspectives in Biology

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Posttranscriptional Crossregulation between Drosha and DGCR8

(2009) Jinju Han et al.   CELL

Targeting Inflammatory Pathways for Prevention and Therapy of Cancer: Short-Term Friend, Long-Term Foe

(2009) B. B. Aggarwal et al.   CLINICAL CANCER RESEARCH

Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

(2009) Mitchell Guttman et al.   NATURE

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Infections and cancer: Established associations and new hypotheses

(2008) Catherine de Martel et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Genes and genetic networks responsive to mild hyperthermia in human lymphoma U937 cells

(2008) Yoshiaki Tabuchi et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Primary microRNA transcripts are processed co-transcriptionally

(2008) Mariangela Morlando et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY