Small Noncoding RNAs in Reproduction and Infertility

Sperm-borne miR-202 targets SEPT7 and regulates first cleavage of bovine embryos via cytoskeletal remodeling

(2021) Mengyun Wang et al.   DEVELOPMENT

Integration of sperm ncRNA-directed DNA methylation and DNA methylation-directed histone retention in epigenetic transgenerational inheritance

(2021) Daniel Beck et al.   Epigenetics & Chromatin

Long first exons and epigenetic marks distinguish conserved pachytene piRNA clusters from other mammalian genes

(2021) Tianxiong Yu et al.   Nature Communications

MicroRNA expression profiles in the seminal plasma of nonobstructive azoospermia patients with different histopathologic patterns

(2021) Wei Zhang et al.   FERTILITY AND STERILITY

Levels of seminal tRNA-derived fragments from normozoospermic men correlate with the success rate of ART

(2021) Julieta B Grosso et al.   MOLECULAR HUMAN REPRODUCTION

Hamster PIWI proteins bind to piRNAs with stage-specific size variations during oocyte maturation

(2021) Kyoko Ishino et al.   NUCLEIC ACIDS RESEARCH

Extracellular vesicle cargo of the male reproductive tract and the paternal preconception environment

(2021) Ahmet Ayaz et al.   Systems Biology in Reproductive Medicine

Sperm microRNAs confer depression susceptibility to offspring

(2021) Yanbo Wang et al.   Science Advances

Small Non-Coding-RNA in Gynecological Malignancies

(2021) Shailendra Kumar Dhar Dwivedi et al.   Cancers

Paternal Exposure to PM2.5 Programs Offspring’s Energy Homeostasis

(2021) Minjie Chen et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Preconceptional smoking alters spermatozoal miRNAs of murine fathers and affects offspring’s body weight

(2021) Barbara Hammer et al.   INTERNATIONAL JOURNAL OF OBESITY

PANDORA-seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications

(2021) Junchao Shi et al.   NATURE CELL BIOLOGY

Computational meta-analysis of ribosomal RNA fragments: potential targets and interaction mechanisms

(2021) Lingyu Guan et al.   NUCLEIC ACIDS RESEARCH

Oocyte age and preconceptual alcohol use are highly correlated with epigenetic imprinting of a noncoding RNA (nc886)

(2021) Brittany L. Carpenter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Insight on the Role of Altered Function and Expression of Exosomes and MicroRNAs in Female Reproductive Diseases

(2021) Maryam Javadi et al.   Reproductive Sciences

Sperm acrosome overgrowth and infertility in mice lacking chromosome 18 pachytene piRNA

(2021) Heejin Choi et al.   PLoS Genetics

Paternal multigenerational exposure to an obesogenic diet drives epigenetic predisposition to metabolic diseases in mice

(2021) Georges Raad et al.   eLife

Paternal High-Protein Diet Programs Offspring Insulin Sensitivity in a Sex-Specific Manner

(2021) Pengfei Gong et al.   Biomolecules

Widespread formation of double-stranded RNAs in testis

(2021) Andreas Werner et al.   GENOME RESEARCH

Small RNA expression and miRNA modification dynamics in human oocytes and early embryos

(2021) Pauliina Paloviita et al.   GENOME RESEARCH

Global profiling of RNA-binding protein target sites by LACE-seq

(2021) Ruibao Su et al.   NATURE CELL BIOLOGY

The Complicated Effects of Extracellular Vesicles and Their Cargos on Embryo Implantation

(2021) Nan-Xing Jiang et al.   Frontiers in Endocrinology

Small RNA-Sequencing: Approaches and Considerations for miRNA Analysis

(2021) Sarka Benesova et al.   Diagnostics

Origins and evolving functionalities of tRNA-derived small RNAs

(2021) Qi Chen et al.   TRENDS IN BIOCHEMICAL SCIENCES

MicroRNA expression profile analysis in sperm reveals hsa-mir-191 as an auspicious omen of in vitro fertilization

(2020) Hua Xu et al.   BMC GENOMICS

The PIWI protein Aubergine recruits eIF3 to activate translation in the germ plasm

(2020) Anne Ramat et al.   CELL RESEARCH

Zucchini consensus motifs determine the mechanism of pre-piRNA production

(2020) Natsuko Izumi et al.   NATURE

Human sperm RNA code senses dietary sugar

(2020) Ying Zhang et al.   Nature Reviews Endocrinology

Histone Post-Translational Modifications and CircRNAs in Mouse and Human Spermatozoa: Potential Epigenetic Marks to Assess Human Sperm Quality

(2020) Teresa Chioccarelli et al.   Journal of Clinical Medicine

Ribosomal RNA fragmentation into short RNAs (rRFs) is modulated in a sex- and population of origin-specific manner

(2020) Tess Cherlin et al.   BMC BIOLOGY

MicroRNAs in combined spent culture media and sperm are associated with embryo quality and pregnancy outcome

(2020) Masood Abu-Halima et al.   FERTILITY AND STERILITY

ATF7-Dependent Epigenetic Changes Are Required for the Intergenerational Effect of a Paternal Low-Protein Diet

(2020) Keisuke Yoshida et al.   MOLECULAR CELL

A Twist between ROS and Sperm-Mediated Intergenerational Epigenetic Inheritance

(2020) Xudong Zhang et al.   MOLECULAR CELL

Epigenetic Transgenerational Inheritance of Obesity Susceptibility

(2020) Stephanie E. King et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Reproductive tract extracellular vesicles are sufficient to transmit intergenerational stress and program neurodevelopment

(2020) Jennifer C. Chan et al.   Nature Communications

The Role of the Epididymis and the Contribution of Epididymosomes to Mammalian Reproduction

(2020) Emma R. James et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Comprehensive analysis of soluble RNAs in human embryo culture media and blastocoel fluid

(2020) Kirstine Kirkegaard et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Early cleavage of preimplantation embryos is regulated by tRNAGln-TTG–derived small RNAs present in mature spermatozoa

(2020) Xiaoxu Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Emerging roles for noncoding RNAs in female sex steroids and reproductive disease

(2020) Runju Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The evolutionarily conserved piRNA-producing locus pi6 is required for male mouse fertility

(2020) Pei-Hsuan Wu et al.   NATURE GENETICS

CircRNA Role and circRNA-Dependent Network (ceRNET) in Asthenozoospermia

(2020) Francesco Manfrevola et al.   Frontiers in Endocrinology

Involvement of circulating factors in the transmission of paternal experiences through the germline

(2020) Gretchen Steenwyk et al.   EMBO JOURNAL

Extracellular vesicles miRNA-21: a potential therapeutic tool in premature ovarian dysfunction

(2020) Eman Thabet et al.   MOLECULAR HUMAN REPRODUCTION

MNDR v3.0: mammal ncRNA–disease repository with increased coverage and annotation

(2020) Lin Ning et al.   NUCLEIC ACIDS RESEARCH

From Sperm Motility to Sperm-Borne microRNA Signatures: New Approaches to Predict Male Fertility Potential

(2020) Maíra Bianchi Rodrigues Alves et al.   Frontiers in Cell and Developmental Biology

Sperm Head Preparation and Genetic Background Affect Caput Sperm ICSI Embryo Viability: Cauda-Enriched miRNAs Only Essential in Specific Conditions

(2020) Colin C. Conine et al.   DEVELOPMENTAL CELL

Both Cauda and Caput Epididymal Sperm Are Capable of Supporting Full-Term Development in FVB and CD-1 Mice

(2020) Yue Wang et al.   DEVELOPMENTAL CELL

Small Noncoding RNA Signatures for Determining the Developmental Potential of an Embryo at the Morula Stage

(2020) Angelika Timofeeva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Male infertility

(2020) Ashok Agarwal et al.   LANCET

TET2 chemically modifies tRNAs and regulates tRNA fragment levels

(2020) Chongsheng He et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Extracellular vesicles, microRNA and the preimplantation embryo: non-invasive clues of embryo well-being

(2020) David Connor Hawke et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Changes in miRNA levels of sperm and small extracellular vesicles of seminal plasma are associated with transient scrotal heat stress in bulls

(2020) Maíra Bianchi Rodrigues Alves et al.   THERIOGENOLOGY

Impact of Parental Exposure on Offspring Health in Humans

(2020) Ali Jawaid et al.   TRENDS IN GENETICS

Epigenetics in Human Obesity and Type 2 Diabetes

(2019) Charlotte Ling et al.   Cell Metabolism

Maternal overnutrition programs hedonic and metabolic phenotypes across generations through sperm tsRNAs

(2019) Gitalee Sarker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive circRNA/miRNA/mRNA analysis reveals circRNAs protect against toxicity induced by BPA in GC-2 cells

(2019) Hui-Min Li et al.   Epigenomics

Epididymal small non‐coding RNA studies: progress over the past decade

(2019) C. Chu et al.   Andrology

Identification of small non-coding RNAs as sperm quality biomarkers for in vitro fertilization

(2019) Minmin Hua et al.   Cell Discovery

Caput Epididymidal Mouse Sperm Support Full Development

(2019) Dongjie Zhou et al.   DEVELOPMENTAL CELL

Sperm RNA code programmes the metabolic health of offspring

(2019) Yunfang Zhang et al.   Nature Reviews Endocrinology

Single-cell CAS-seq reveals a class of short PIWI-interacting RNAs in human oocytes

(2019) Qiyuan Yang et al.   Nature Communications

Role of microRNA in the Pathogenesis of Polycystic Ovary Syndrome

(2019) Zhuo Chen et al.   DNA AND CELL BIOLOGY

Non-coding RNAs as biomarkers in liquid biopsies with a special emphasis on extracellular vesicles in urological malignancies

(2019) Philip Zeuschner et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

Alterations in sperm-inherited noncoding RNAs associate with late-term fetal growth restriction induced by preconception paternal alcohol use

(2019) Yudhishtar Bedi et al.   REPRODUCTIVE TOXICOLOGY

A Translation-Activating Function of MIWI/piRNA during Mouse Spermiogenesis

(2019) Peng Dai et al.   CELL

Human sperm displays rapid responses to diet

(2019) Daniel Nätt et al.   PLOS BIOLOGY

Restricted and non-essential redundancy of RNAi and piRNA pathways in mouse oocytes

(2019) Eliska Taborska et al.   PLoS Genetics

Systematic comparison of small RNA library preparation protocols for next-generation sequencing

(2018) Cloelia Dard-Dascot et al.   BMC GENOMICS

PNLDC1, mouse pre‐piRNA Trimmer, is required for meiotic and post‐meiotic male germ cell development

(2018) Toru Nishimura et al.   EMBO REPORTS

Influence of follicular fluid and cumulus cells on oocyte quality: clinical implications

(2018) M. G. Da Broi et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs

(2018) Yunfang Zhang et al.   NATURE CELL BIOLOGY

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control

(2018) Jin-Yu Yang et al.   Nature Communications

RNA-Dependent Intergenerational Inheritance of Enhanced Synaptic Plasticity after Environmental Enrichment

(2018) Eva Benito et al.   Cell Reports

Endurance training remodels sperm-borne small RNA expression and methylation at neurological gene hotspots

(2018) Lars R. Ingerslev et al.   Clinical Epigenetics

Heavy Chronic Intermittent Ethanol Exposure Alters Small Noncoding RNAs in Mouse Sperm and Epididymosomes

(2018) Gregory R. Rompala et al.   Frontiers in Genetics

miR-155 and miR-122 Expression of Spermatozoa in Obese Subjects

(2018) Paulina López et al.   Frontiers in Genetics

Characteristics of the Epididymal Luminal Environment Responsible for Sperm Maturation and Storage

(2018) Wei Zhou et al.   Frontiers in Endocrinology

The landscape of mitochondrial small non-coding RNAs in the PGCs of male mice, spermatogonia, gametes and in zygotes

(2018) Eduardo Larriba et al.   BMC GENOMICS

Small RNAs Are Trafficked from the Epididymis to Developing Mammalian Sperm

(2018) Upasna Sharma et al.   DEVELOPMENTAL CELL

Small RNAs Gained during Epididymal Transit of Sperm Are Essential for Embryonic Development in Mice

(2018) Colin C. Conine et al.   DEVELOPMENTAL CELL

The epidemiology of obesity

(2018) Yu Chung Chooi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Proteomic profiling of mouse epididymosomes reveals their contributions to post-testicular sperm maturation

(2018) Brett Nixon et al.   MOLECULAR & CELLULAR PROTEOMICS

Regulation of microRNA function in animals

(2018) Luca F. R. Gebert et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Transgenerational transmission of hedonic behaviors and metabolic phenotypes induced by maternal overnutrition

(2018) Gitalee Sarker et al.   Translational Psychiatry

m6A mRNA modification regulates mammalian spermatogenesis

(2018) Zhen Lin et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The role of microRNAs in human embryo implantation: a review

(2018) Anthea B. M. Paul et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma

(2018) K. Gapp et al.   MOLECULAR PSYCHIATRY

PIWI-interacting RNAs: small RNAs with big functions

(2018) Deniz M. Ozata et al.   NATURE REVIEWS GENETICS

Liquid biopsy in ovarian cancer: the potential of circulating miRNAs and exosomes

(2018) Lydia Giannopoulou et al.   Translational Research

Extracellular microRNAs profile in human follicular fluid and IVF outcomes

(2018) Rosie M. Martinez et al.   Scientific Reports

Disrupted sperm mirna expression profiles revealed a fingerprint of impaired spermatogenesis in oligozoospermia males

(2017) N.I. McCubbin et al.   FERTILITY AND STERILITY

Obesity and female infertility: potential mediators of obesity's impact

(2017) Darcy E. Broughton et al.   FERTILITY AND STERILITY

Obesity, male infertility, and the sperm epigenome

(2017) James R. Craig et al.   FERTILITY AND STERILITY

RdRP-synthesized antisense ribosomal siRNAs silence pre-rRNA via the nuclear RNAi pathway

(2017) Xufei Zhou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes

(2017) Yuka Kabayama et al.   NUCLEIC ACIDS RESEARCH

The biogenesis pathway of tRNA-derived piRNAs in Bombyx germ cells

(2017) Shozo Honda et al.   NUCLEIC ACIDS RESEARCH

ALKBH5-dependent m6A demethylation controls splicing and stability of long 3′-UTR mRNAs in male germ cells

(2017) Chong Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the small non-protein-coding RNA profile of mouse spermatozoa reveals specific enrichment of piRNAs within mature spermatozoa

(2017) Kate Hutcheon et al.   RNA Biology

MicroRNA dynamics at the onset of primordial germ and somatic cell sex differentiation during mouse embryonic gonad development

(2017) Daniel Fernández-Pérez et al.   RNA

A sequence of 28S rRNA-derived small RNAs is enriched in mature sperm and various somatic tissues and possibly associates with inflammation

(2017) Chen Chu et al.   Journal of Molecular Cell Biology

PNLDC1 is essential for piRNA 3′ end trimming and transposon silencing during spermatogenesis in mice

(2017) Deqiang Ding et al.   Nature Communications

RdRP-synthesized antisense ribosomal siRNAs silence pre-rRNA via the nuclear RNAi pathway

(2017) Xufei Zhou et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exercise alters mouse sperm small noncoding RNAs and induces a transgenerational modification of male offspring conditioned fear and anxiety

(2017) A K Short et al.   Translational Psychiatry

Micro-ribonucleic acids and extracellular vesicles repertoire in the spent culture media is altered in women undergoing In Vitro Fertilization

(2017) Masood Abu-Halima et al.   Scientific Reports

SpermBase: A Database for Sperm-Borne RNA Contents

(2016) A. Schuster et al.   BIOLOGY OF REPRODUCTION

Obesity and Bariatric Surgery Drive Epigenetic Variation of Spermatozoa in Humans

(2016) Ida Donkin et al.   Cell Metabolism

MicroRNAs in spent blastocyst culture medium are derived from trophectoderm cells and can be explored for human embryo reproductive competence assessment

(2016) Antonio Capalbo et al.   FERTILITY AND STERILITY

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Theo Vos et al.   LANCET

Expression dynamics, relationships, and transcriptional regulations of diverse transcripts in mouse spermatogenic cells

(2016) Xiwen Lin et al.   RNA Biology

Biogenesis and Function of Transfer RNA-Related Fragments (tRFs)

(2016) Pankaj Kumar et al.   TRENDS IN BIOCHEMICAL SCIENCES

Increased N 6 -methyladenosine in Human Sperm RNA as a Risk Factor for Asthenozoospermia

(2016) Ying Yang et al.   Scientific Reports

Elevated paternal glucocorticoid exposure alters the small noncoding RNA profile in sperm and modifies anxiety and depressive phenotypes in the offspring

(2016) A K Short et al.   Translational Psychiatry

Highly sensitive sequencing reveals dynamic modifications and activities of small RNAs in mouse oocytes and early embryos

(2016) Q. Yang et al.   Science Advances

Circulating microRNAs in follicular fluid, powerful tools to explore in vitro fertilization process

(2016) E. Scalici et al.   Scientific Reports

Systematic characterization of seminal plasma piRNAs as molecular biomarkers for male infertility

(2016) Yeting Hong et al.   Scientific Reports

Identification and characterization of human testis derived circular RNAs and their existence in seminal plasma

(2016) Wei-Wei Dong et al.   Scientific Reports

Drinking beyond a lifetime: New and emerging insights into paternal alcohol exposure on subsequent generations

(2015) Andrey Finegersh et al.   ALCOHOL

PIWI-Interacting RNA: Its Biogenesis and Functions

(2015) Yuka W. Iwasaki et al.   Annual Review of Biochemistry

Extracellular microRNAs from the epididymis as potential mediators of cell-to-cell communication

(2015) Clémence Belleannée   ASIAN JOURNAL OF ANDROLOGY

HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events

(2015) Claudio R. Alarcón et al.   CELL

MIWI and piRNA-mediated cleavage of messenger RNAs in mouse testes

(2015) Peng Zhang et al.   CELL RESEARCH

m6A RNA Methylation Is Regulated by MicroRNAs and Promotes Reprogramming to Pluripotency

(2015) Tong Chen et al.   Cell Stem Cell

Sperm-borne miRNAs and endo-siRNAs are important for fertilization and preimplantation embryonic development

(2015) Shuiqiao Yuan et al.   DEVELOPMENT

piRNA-directed cleavage of meiotic transcripts regulates spermatogenesis

(2015) Wee Siong Sho Goh et al.   GENES & DEVELOPMENT

Dgcr8 and Dicer are essential for sex chromosome integrity during meiosis in males

(2015) A. J. Modzelewski et al.   JOURNAL OF CELL SCIENCE

N6-methyladenosine marks primary microRNAs for processing

(2015) Claudio R. Alarcón et al.   NATURE

Transgenerational epigenetic programming via sperm microRNA recapitulates effects of paternal stress

(2015) Ali B. Rodgers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A deeply conserved, noncanonical miRNA hosted by ribosomal DNA

(2015) Li-Ling Chak et al.   RNA

Diversity and functional convergence of small noncoding RNAs in male germ cell differentiation and fertilization

(2015) Jesús García-López et al.   RNA

Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

(2015) Q. Chen et al.   SCIENCE

piRNA-guided slicing specifies transcripts for Zucchini-dependent, phased piRNA biogenesis

(2015) F. Mohn et al.   SCIENCE

piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production

(2015) B. W. Han et al.   SCIENCE

Biogenesis and function of tRNA fragments during sperm maturation and fertilization in mammals

(2015) U. Sharma et al.   SCIENCE

Dissecting tRNA-derived fragment complexities using personalized transcriptomes reveals novel fragment classes and unexpected dependencies

(2015) Aristeidis G. Telonis et al.   Oncotarget

MiRNA-320 in the human follicular fluid is associated with embryo quality in vivo and affects mouse embryonic development in vitro

(2015) Ruizhi Feng et al.   Scientific Reports

Piwi Proteins and piRNAs in Mammalian Oocytes and Early Embryos

(2015) Elke F. Roovers et al.   Cell Reports

HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse

(2015) Shu Ly Lim et al.   PLoS Genetics

mir-34b/c and mir-449a/b/c are required for spermatogenesis, but not for the first cleavage division in mice

(2015) S. Yuan et al.   Biology Open

RNA-mediated paternal heredity of diet-induced obesity and metabolic disorders

(2015) Valérie Grandjean et al.   Scientific Reports

Meta-analysis of tRNA derived RNA fragments reveals that they are evolutionarily conserved and associate with AGO proteins to recognize specific RNA targets

(2014) Pankaj Kumar et al.   BMC BIOLOGY

Transgenerational Epigenetic Inheritance: Myths and Mechanisms

(2014) Edith Heard et al.   CELL

Pachytene piRNAs instruct massive mRNA elimination during late spermiogenesis

(2014) Lan-Tao Gou et al.   CELL RESEARCH

Human embryos secrete microRNAs into culture media—a potential biomarker for implantation

(2014) Evan M. Rosenbluth et al.   FERTILITY AND STERILITY

MicroRNAs and spermatogenesis

(2014) Noora Kotaja   FERTILITY AND STERILITY

Retrotransposons and pseudogenes regulate mRNAs and lncRNAs via the piRNA pathway in the germline

(2014) Toshiaki Watanabe et al.   GENOME RESEARCH

Altered microRNA and gene expression in the follicular fluid of women with polycystic ovary syndrome

(2014) Lauren W. Roth et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Evaluation of quantitative miRNA expression platforms in the microRNA quality control (miRQC) study

(2014) Pieter Mestdagh et al.   NATURE METHODS

Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice

(2014) Katharina Gapp et al.   NATURE NEUROSCIENCE

Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions

(2014) L. Vojtech et al.   NUCLEIC ACIDS RESEARCH

Definition and Epidemiology of Unexplained Infertility

(2014) Tarek A. Gelbaya et al.   OBSTETRICAL & GYNECOLOGICAL SURVEY

Germ Cell-Specific Targeting of DICER or DGCR8 Reveals a Novel Role for Endo-siRNAs in the Progression of Mammalian Spermatogenesis and Male Fertility

(2014) Céline Zimmermann et al.   PLoS One

Evolution of DOHaD: the impact of environmental health sciences

(2014) A. C. Haugen et al.   Journal of Developmental Origins of Health and Disease

Small noncoding RNAs and male infertility

(2014) Lan-Tao Gou et al.   Wiley Interdisciplinary Reviews-RNA

A Retrotransposon-Driven Dicer Isoform Directs Endogenous Small Interfering RNA Production in Mouse Oocytes

(2013) Matyas Flemr et al.   CELL

The nuage mediates retrotransposon silencing in mouse primordial ovarian follicles

(2013) A. K. Lim et al.   DEVELOPMENT

Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline

(2013) Jonathan P Saxe et al.   EMBO JOURNAL

Altered microRNA expression profiles of human spermatozoa in patients with different spermatogenic impairments

(2013) Masood Abu-Halima et al.   FERTILITY AND STERILITY

microRNA signature is altered in both human epididymis and seminal microvesicles following vasectomy

(2013) Clémence Belleannée et al.   HUMAN REPRODUCTION

Identification of MicroRNAs in Human Follicular Fluid: Characterization of MicroRNAs That Govern Steroidogenesis in Vitro and Are Associated With Polycystic Ovary Syndrome in Vivo

(2013) Qing Sang et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Paternal Stress Exposure Alters Sperm MicroRNA Content and Reprograms Offspring HPA Stress Axis Regulation

(2013) A. B. Rodgers et al.   JOURNAL OF NEUROSCIENCE

An Ancient Transcription Factor Initiates the Burst of piRNA Production during Early Meiosis in Mouse Testes

(2013) Xin Zhiguo Li et al.   MOLECULAR CELL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Differential roles of human Dicer-binding proteins TRBP and PACT in small RNA processing

(2013) Ho Young Lee et al.   NUCLEIC ACIDS RESEARCH

Profiling and Identification of Small rDNA-Derived RNAs and Their Potential Biological Functions

(2013) Haibin Wei et al.   PLoS One

Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice

(2013) R. R. Pandey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epididymosomes, prostasomes, and liposomes: their roles in mammalian male reproductive physiology

(2013) Robert Sullivan et al.   REPRODUCTION

UAP56 Couples piRNA Clusters to the Perinuclear Transposon Silencing Machinery

(2012) Fan Zhang et al.   CELL

Developmental origins of non-communicable disease: Implications for research and public health

(2012) Robert Barouki et al.   Environmental Health

Smoking induces differential miRNA expression in human spermatozoa: A potential transgenerational epigenetic concern?

(2012) Emma L. Marczylo et al.   Epigenetics

MicroRNA expression in the human blastocyst

(2012) Evan M. Rosenbluth et al.   FERTILITY AND STERILITY

The RNase III Enzyme DROSHA Is Essential for MicroRNA Production and Spermatogenesis

(2012) Qiuxia Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis

(2012) Francesca Tuorto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Deregulated Sex Chromosome Gene Expression with Male Germ Cell-Specific Loss of Dicer1

(2012) Anne R. Greenlee et al.   PLoS One

IsomiRs – the overlooked repertoire in the dynamic microRNAome

(2012) Corine T. Neilsen et al.   TRENDS IN GENETICS

Altered Profile of Seminal Plasma MicroRNAs in the Molecular Diagnosis of Male Infertility

(2011) C. Wang et al.   CLINICAL CHEMISTRY

A-MYB (MYBL1) transcription factor is a master regulator of male meiosis

(2011) E. Bolcun-Filas et al.   DEVELOPMENT

MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline

(2011) Toshiaki Watanabe et al.   DEVELOPMENTAL CELL

The Many Faces of RNAi

(2011) René F. Ketting   DEVELOPMENTAL CELL

The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements

(2011) Serena De Fazio et al.   NATURE

Miwi catalysis is required for piRNA amplification-independent LINE1 transposon silencing

(2011) Michael Reuter et al.   NATURE

Characterization of extracellular circulating microRNA

(2011) Andrey Turchinovich et al.   NUCLEIC ACIDS RESEARCH

Sperm-borne microRNA-34c is required for the first cleavage division in mouse

(2011) W.-M. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Male germ cells express abundant endogenous siRNAs

(2011) Rui Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects

(2011) L. A. Medeiros et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

(2010) Benjamin R. Carone et al.   CELL

MicroRNA Activity Is Suppressed in Mouse Oocytes

(2010) Jun Ma et al.   CURRENT BIOLOGY

MicroRNA Function Is Globally Suppressed in Mouse Oocytes and Early Embryos

(2010) Nayoung Suh et al.   CURRENT BIOLOGY

Export of microRNAs and microRNA-protective protein by mammalian cells

(2010) Kai Wang et al.   NUCLEIC ACIDS RESEARCH

Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expression

(2010) A. Git et al.   RNA

Human tRNA-derived small RNAs in the global regulation of RNA silencing

(2010) D. Haussecker et al.   RNA

A Broadly Conserved Pathway Generates 3′UTR-Directed Primary piRNAs

(2009) Nicolas Robine et al.   CURRENT BIOLOGY

The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of embryonic and adult growth

(2009) V. Grandjean et al.   DEVELOPMENT

Aberration of blastocyst microRNA expression is associated with human infertility

(2009) Blair McCallie et al.   FERTILITY AND STERILITY

A novel class of small RNAs: tRNA-derived RNA fragments (tRFs)

(2009) Yong Sun Lee et al.   GENES & DEVELOPMENT

The RNase Rny1p cleaves tRNAs and promotes cell death during oxidative stress inSaccharomyces cerevisiae

(2009) Debrah M. Thompson et al.   JOURNAL OF CELL BIOLOGY

Angiogenin cleaves tRNA and promotes stress-induced translational repression

(2009) Satoshi Yamasaki et al.   JOURNAL OF CELL BIOLOGY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Loss of the Mili-interacting Tudor domain–containing protein-1 activates transposons and alters the Mili-associated small RNA profile

(2009) Michael Reuter et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs

(2009) C. Cole et al.   RNA

RNA Induction and Inheritance of Epigenetic Cardiac Hypertrophy in the Mouse

(2008) Kay D. Wagner et al.   DEVELOPMENTAL CELL

DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes

(2008) S. Kuramochi-Miyagawa et al.   GENES & DEVELOPMENT

Mouse ES cells express endogenous shRNAs, siRNAs, and other Microprocessor-independent, Dicer-dependent small RNAs

(2008) J. E. Babiarz et al.   GENES & DEVELOPMENT

Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

(2008) Toshiaki Watanabe et al.   NATURE

Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

(2008) Oliver H. Tam et al.   NATURE

An endogenous small interfering RNA pathway in Drosophila

(2008) Benjamin Czech et al.   NATURE

MicroRNA Biogenesis Is Required for Mouse Primordial Germ Cell Development and Spermatogenesis

(2008) Katsuhiko Hayashi et al.   PLoS One

tRNA cleavage is a conserved response to oxidative stress in eukaryotes

(2008) D. M. Thompson et al.   RNA

Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells

(2008) M. Ghildiyal et al.   SCIENCE