Extracellular vesicles, microRNA and the preimplantation embryo: non-invasive clues of embryo well-being

Impact of long-term storage and freeze-thawing on eight circulating microRNAs in plasma samples

(2020) Pamela R. Matias-Garcia et al.   PLoS One

Blastocyst collapse as an embryo marker of low implantation potential: a time-lapse multicentre study

(2020) Romualdo Sciorio et al.   ZYGOTE

A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum

(2020) K. Brennan et al.   Scientific Reports

Identification and Characterization of Extracellular Vesicles and Its DNA Cargo Secreted During Murine Embryo Development

(2020) Blanca Simon et al.   Genes

Individually cultured bovine embryos produce extracellular vesicles that have the potential to be used as non-invasive embryo quality markers

(2020) Keerthie Dissanayake et al.   THERIOGENOLOGY

Identification of extracellular vesicles and characterization of miRNA expression profiles in human blastocoel fluid

(2019) R. Battaglia et al.   Scientific Reports

An estimate of the total number of true human miRNAs

(2019) Julia Alles et al.   NUCLEIC ACIDS RESEARCH

Clinical application of embryo aneuploidy testing by next-generation sequencing

(2019) Carmen Rubio et al.   BIOLOGY OF REPRODUCTION

Ticket to a bubble ride: Cargo sorting into exosomes and extracellular vesicles

(2019) Sushma Anand et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Flow Cytometric Analysis of Nanoscale Biological Particles and Organelles

(2019) Hong Lian et al.   Annual Review of Analytical Chemistry

Bovine Embryo-Secreted microRNA-30c Is a Potential Non-invasive Biomarker for Hampered Preimplantation Developmental Competence

(2019) Xiaoyuan Lin et al.   Frontiers in Genetics

Minimally invasive preimplantation genetic testing using blastocyst culture medium

(2019) Jiao Jiao et al.   HUMAN REPRODUCTION

MicroRNA Profiling During Neural Differentiation of Induced Pluripotent Stem Cells

(2019) Katarzyna Kulcenty et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Expression of miR‐Let‐7a, miR‐15a, miR‐16‐1, and their target genes in fresh and vitrified embryos and its surrounding culture media for noninvasive embryo assessment

(2019) Fezzeh Heidari et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis

(2019) Laura M. Doyle et al.   Cells

Definition and validation of a custom protocol to detect miRNAs in the spent media after blastocyst culture: searching for biomarkers of implantation

(2019) Danilo Cimadomo et al.   HUMAN REPRODUCTION

Bta-miR-10b Secreted by Bovine Embryos Negatively Impacts Preimplantation Embryo Quality

(2019) Xiaoyuan Lin et al.   Frontiers in Genetics

Non-invasive preimplantation genetic testing (niPGT): the next revolution in reproductive genetics?

(2019) Megan Leaver et al.   HUMAN REPRODUCTION UPDATE

Identifying biomarkers for predicting successful embryo implantation: applying single to multi-OMICs to improve reproductive outcomes

(2019) Purificación Hernández-Vargas et al.   HUMAN REPRODUCTION UPDATE

MicroRNAs as Clinical Biomarkers and Therapeutic Tools in Perioperative Medicine

(2018) Simone Kreth et al.   ANESTHESIA AND ANALGESIA

Evaluation of a novel non-invasive preimplantation genetic screening approach

(2018) Valeriy Kuznyetsov et al.   PLoS One

MicroRNA expression in bovine preimplantation embryos

(2018) Debra K. Berg et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

NGS Analysis of Human Embryo Culture Media Reveals miRNAs of Extra Embryonic Origin

(2018) Immaculada Sánchez-Ribas et al.   Reproductive Sciences

PIBF+ extracellular vesicles from mouse embryos affect IL-10 production by CD8+ cells

(2018) Eva Pallinger et al.   Scientific Reports

Preimplantation Genetic Screening with Spent Culture Medium/Blastocoel Fluid for in Vitro Fertilization

(2018) Penghao Li et al.   Scientific Reports

Effect of pH, temperature and freezing-thawing on quantity changes and cellular uptake of exosomes

(2018) Yirui Cheng et al.   Protein & Cell

Circulating miRNAs as Predictive Biomarkers of Type 2 Diabetes Mellitus Development in Coronary Heart Disease Patients from the CORDIOPREV Study

(2018) Rosa Jiménez-Lucena et al.   Molecular Therapy-Nucleic Acids

Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation

(2018) Jacob O'Brien et al.   Frontiers in Endocrinology

Isolation and Characterization of Functionally Active Extracellular Vesicles from Culture Medium Conditioned by Bovine Embryos In Vitro

(2018) Krishna Pavani et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Embryotrophic effects of extracellular vesicles derived from outgrowth embryos in pre- and peri-implantation embryonic development in mice

(2018) Jihyun Kim et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Characterizing nuclear and mitochondrial DNA in spent embryo culture media: genetic contamination identified

(2017) Elizabeth R. Hammond et al.   FERTILITY AND STERILITY

An integrated expression atlas of miRNAs and their promoters in human and mouse

(2017) Derek de Rie et al.   NATURE BIOTECHNOLOGY

Identification and characteristics of extracellular vesicles from bovine blastocysts produced in vitro

(2017) Edwin A. Mellisho et al.   PLoS One

A simple and rapid flow cytometry-based assay to identify a competent embryo prior to embryo transfer

(2017) Eva Pallinger et al.   Scientific Reports

Sexual Dimorphism of miRNAs Secreted by Bovine In vitro-produced Embryos

(2017) Nicole Gross et al.   Frontiers in Genetics

Effects of embryo-derived exosomes on the development of bovine cloned embryos

(2017) Pengxiang Qu et al.   PLoS One

The formation of multivesicular bodies in activated blastocysts is influenced by autophagy and FGF signaling in mice

(2017) Hyejin Shin et al.   Scientific Reports

Secretome of in vitro cultured human embryos contains extracellular vesicles that are uptaken by the maternal side

(2017) Elisa Giacomini et al.   Scientific Reports

Micro-ribonucleic acids and extracellular vesicles repertoire in the spent culture media is altered in women undergoing In Vitro Fertilization

(2017) Masood Abu-Halima et al.   Scientific Reports

MicroRNAs in spent blastocyst culture medium are derived from trophectoderm cells and can be explored for human embryo reproductive competence assessment

(2016) Antonio Capalbo et al.   FERTILITY AND STERILITY

Does the addition of time-lapse morphokinetics in the selection of embryos for transfer improve pregnancy rates? A randomized controlled trial

(2016) Linnea R. Goodman et al.   FERTILITY AND STERILITY

Improved implantation rates of day 3 embryo transfers with the use of an automated time-lapse–enabled test to aid in embryo selection

(2016) G. David Adamson et al.   FERTILITY AND STERILITY

Embryo selection using time-lapse analysis (Early Embryo Viability Assessment) in conjunction with standard morphology: a prospective two-center pilot study

(2016) Dorit C. Kieslinger et al.   HUMAN REPRODUCTION

Assessment of human embryo development using morphological criteria in an era of time-lapse, algorithms and ‘OMICS’: is looking good still important?

(2016) David K. Gardner et al.   MOLECULAR HUMAN REPRODUCTION

Morphokinetics of human blastocyst expansion in vitro

(2016) T.T.F. Huang et al.   REPRODUCTIVE BIOMEDICINE ONLINE

The Impact of Biopsy on Human Embryo Developmental Potential during Preimplantation Genetic Diagnosis

(2016) Danilo Cimadomo et al.   Biomed Research International

Validating reference microRNAs for normalizing qRT-PCR data in bovine oocytes and preimplantation embryos

(2015) Mahdi Mahdipour et al.   BMC DEVELOPMENTAL BIOLOGY

Collapse of blastocysts is strongly related to lower implantation success: a time-lapse study

(2015) Julian Marcos et al.   HUMAN REPRODUCTION

Quantitative and qualitative trophectoderm grading allows for prediction of live birth and gender

(2015) Thomas Ebner et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Characterization of microRNA in bovine in vitro culture media associated with embryo quality and development

(2015) Jenna Kropp et al.   JOURNAL OF DAIRY SCIENCE

Human Blastocyst Secreted microRNA Regulate Endometrial Epithelial Cell Adhesion

(2015) Carly Cuman et al.   EBioMedicine

Improvement of Cloned Embryos Development by Co-Culturing with Parthenotes: A Possible Role of Exosomes/Microvesicles for Embryos Paracrine Communication

(2014) Islam M. Saadeldin et al.   Cellular Reprogramming

Human embryos secrete microRNAs into culture media—a potential biomarker for implantation

(2014) Evan M. Rosenbluth et al.   FERTILITY AND STERILITY

Preimplantation genetic screening: back to the future

(2014) S. Mastenbroek et al.   HUMAN REPRODUCTION

Transfer of blastocysts with deviant morphological and morphokinetic parameters at early stages of in-vitro development: a case series

(2014) Astrid Stecher et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Expression of microRNAs in bovine and human pre-implantation embryo culture media

(2014) Jenna Kropp et al.   Frontiers in Genetics

Stability of miRNA in human urine supports its biomarker potential

(2013) Christine Mall et al.   Biomarkers in Medicine

Embryology in the era of proteomics

(2013) Mandy G. Katz-Jaffe et al.   FERTILITY AND STERILITY

Cleavage-stage biopsy significantly impairs human embryonic implantation potential while blastocyst biopsy does not: a randomized and paired clinical trial

(2013) Richard T. Scott et al.   FERTILITY AND STERILITY

Extracellular vesicles: biology and emerging therapeutic opportunities

(2013) Samir EL Andaloussi et al.   NATURE REVIEWS DRUG DISCOVERY

Discovery of pluripotency-associated microRNAs in rabbit preimplantation embryos and embryonic stem-like cells

(2013) Pouneh Maraghechi et al.   REPRODUCTION

Expression dynamics of microRNA biogenesis during preimplantation mouse development

(2012) Jesús García-López et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

MicroRNA expression in the human blastocyst

(2012) Evan M. Rosenbluth et al.   FERTILITY AND STERILITY

Effect of culture medium volume and embryo density on early mouse embryonic development: Tracking the development of the individual embryo

(2012) Shan-Jun Dai et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Sizing and phenotyping of cellular vesicles using Nanoparticle Tracking Analysis

(2011) Rebecca A. Dragovic et al.   Nanomedicine-Nanotechnology Biology and Medicine

Sperm-borne microRNA-34c is required for the first cleavage division in mouse

(2011) W.-M. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Robust MicroRNA Stability in Degraded RNA Preparations from Human Tissue and Cell Samples

(2010) M. Jung et al.   CLINICAL CHEMISTRY

The role of miRNAs and endogenous siRNAs in maternal-to-zygotic reprogramming and the establishment of pluripotency

(2010) Petr Svoboda et al.   EMBO REPORTS

Small RNA class transition from siRNA/piRNA to miRNA during pre-implantation mouse development

(2010) Yusuke Ohnishi et al.   NUCLEIC ACIDS RESEARCH

Aberration of blastocyst microRNA expression is associated with human infertility

(2009) Blair McCallie et al.   FERTILITY AND STERILITY

MicroRNAs: tools for cancer diagnostics

(2009) T Paranjape et al.   GUT

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

MicroRNA expression in preimplantation mouse embryos from Ped gene positive compared to Ped gene negative mice

(2008) Michael J. Byrne et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Sequence Relationships among C. elegans, D. melanogaster and Human microRNAs Highlight the Extensive Conservation of microRNAs in Biology

(2008) Carolina Ibáñez-Ventoso et al.   PLoS One