Tryptophan Metabolites, Cytokines, and Fatty Acid Binding Protein 2 in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

Insights from Invasive Cardiopulmonary Exercise Testing of Patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

(2021) Phillip Joseph et al.   CHEST

Dysregulated Provision of Oxidisable Substrates to the Mitochondria in ME/CFS Lymphoblasts

(2021) Daniel Missailidis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ME/CFS: whole genome sequencing uncovers a misclassified case of glycogen storage disease type 13 previously diagnosed as ME/CFS

(2021) Donna Brown et al.   MOLECULAR GENETICS AND METABOLISM

Potential role of microbiome in Chronic Fatigue Syndrome/Myalgic Encephalomyelits (CFS/ME)

(2021) Giuseppe Francesco Damiano Lupo et al.   Scientific Reports

Tryptophan, kynurenine pathway, and diabetic ketoacidosis in type 1 diabetes

(2021) William H. Hoffman et al.   PLoS One

Kynurenine metabolites and ratios differ between Chronic Fatigue Syndrome, Fibromyalgia, and healthy controls

(2021) Nina Groven et al.   PSYCHONEUROENDOCRINOLOGY

Monitoring the kynurenine system: Concentrations, ratios or what else?

(2021) Masaru Tanaka et al.   Advances in Clinical and Experimental Medicine

Depression and Obesity in Patients With Psoriasis and Psoriatic Arthritis: Is IL-17-Mediated Immune Dysregulation the Connecting Link?

(2021) Efterpi Zafiriou et al.   Frontiers in Immunology

A map of metabolic phenotypes in patients with myalgic encephalomyelitis/chronic fatigue syndrome

(2021) Fredrik Hoel et al.   JCI Insight

Immune Influencers in Action: Metabolites and Enzymes of the Tryptophan-Kynurenine Metabolic Pathway

(2021) Masaru Tanaka et al.   Biomedicines

Systematic review and meta-analysis of the prevalence of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)

(2020) Eun-Jin Lim et al.   Journal of Translational Medicine

The kynurenine connection: how exercise shifts muscle tryptophan metabolism and affects energy homeostasis, the immune system, and the brain

(2020) Kyle S. Martin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Prenatal IL-6 levels and activation of the tryptophan to kynurenine pathway are associated with depressive but not anxiety symptoms across the perinatal and the post-partum period in a low-risk sample

(2020) Sarah Nazzari et al.   BRAIN BEHAVIOR AND IMMUNITY

A SWATH-MS analysis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome peripheral blood mononuclear cell proteomes reveals mitochondrial dysfunction

(2020) Eiren Sweetman et al.   Journal of Translational Medicine

Neuroimaging characteristics of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): a systematic review

(2020) Zack Y. Shan et al.   Journal of Translational Medicine

Brain-immune crosstalk in the treatment of major depressive disorder

(2020) Igor Branchi et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Searching for Peripheral Biomarkers in Neurodegenerative Diseases: The Tryptophan-Kynurenine Metabolic Pathway

(2020) Nóra Török et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroinflammation and Cytokines in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): A Critical Review of Research Methods

(2019) Michael B. VanElzakker et al.   Frontiers in Neurology

Onset Patterns and Course of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

(2019) Lily Chu et al.   Frontiers in Pediatrics

Varied Presentation of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and the Needs for Classification and Clinician Education: A Case Series

(2019) Eva Martín-Martínez et al.   CLINICAL THERAPEUTICS

Cytokine Networks in the Pathophysiology of Inflammatory Bowel Disease

(2019) Matthias Friedrich et al.   IMMUNITY

Cholinergic Control of Inflammation, Metabolic Dysfunction, and Cognitive Impairment in Obesity-Associated Disorders: Mechanisms and Novel Therapeutic Opportunities

(2019) Eric H. Chang et al.   Frontiers in Neuroscience

A systematic review of cytokines in chronic fatigue syndrome/myalgic encephalomyelitis/systemic exertion intolerance disease (CFS/ME/SEID)

(2019) Matthew Corbitt et al.   BMC Neurology

Focus on the essentials: tryptophan metabolism and the microbiome-gut-brain axis

(2019) Cassandra Elise Gheorghe et al.   CURRENT OPINION IN PHARMACOLOGY

Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring

(2019) Valentina Pucino et al.   Cell Metabolism

Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations

(2019) Alexandra H. Mandarano et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuroinflammation and the Immune-Kynurenine Pathway in Anxiety Disorders

(2018) Yong-Ku Kim et al.   Current Neuropharmacology

The cholinergic anti-inflammatory pathway revisited

(2018) K. Murray et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes

(2018) Fabrizio De Benedetti et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reduced peripheral availability of tryptophan and increased activation of the kynurenine pathway and cortisol correlate with major depression and suicide

(2018) Amel Messaoud et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics

(2018) Dorottya Nagy-Szakal et al.   Scientific Reports

Kynurenic Acid: The Janus-Faced Role of an Immunomodulatory Tryptophan Metabolite and Its Link to Pathological Conditions

(2018) Elisa Wirthgen et al.   Frontiers in Immunology

Glial Activation and Expression of the Serotonin Transporter in Chronic Fatigue Syndrome

(2018) Mami Noda et al.   Frontiers in Psychiatry

Cellular bioenergetics is impaired in patients with chronic fatigue syndrome

(2017) Cara Tomas et al.   PLoS One

Protective Effects of Bifidobacterium on Intestinal Barrier Function in LPS-Induced Enterocyte Barrier Injury of Caco-2 Monolayers and in a Rat NEC Model

(2016) Xiang Ling et al.   PLoS One

Reduced diversity and altered composition of the gut microbiome in individuals with myalgic encephalomyelitis/chronic fatigue syndrome

(2016) Ludovic Giloteaux et al.   Microbiome

Impact of IL-1 inhibition on fatigue associated with autoinflammatory syndromes

(2015) Sujani Yadlapati et al.   Modern Rheumatology

Distinct plasma immune signatures in ME/CFS are present early in the course of illness

(2015) M. Hornig et al.   Science Advances

Neuroinflammation in Patients with Chronic Fatigue Syndrome/Myalgic Encephalomyelitis: An 11C-(R)-PK11195 PET Study

(2014) Y. Nakatomi et al.   JOURNAL OF NUCLEAR MEDICINE

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

Serotonin and GI Disorders: An Update on Clinical and Experimental Studies

(2012) Marcus Manocha et al.   Clinical and Translational Gastroenterology

Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS

(2010) Roberta Benfante et al.   JOURNAL OF NEUROIMMUNOLOGY

Chronic fatigue syndrome: Is it one discrete syndrome or many? Implications for the “one vs. many” functional somatic syndromes debate

(2010) Peter D. White   JOURNAL OF PSYCHOSOMATIC RESEARCH

Further delineation of the 15q13 microdeletion and duplication syndromes: a clinical spectrum varying from non-pathogenic to a severe outcome

(2009) B W M van Bon et al.   JOURNAL OF MEDICAL GENETICS

Hypersensitivity of Aryl Hydrocarbon Receptor-Deficient Mice to Lipopolysaccharide-Induced Septic Shock

(2009) H. Sekine et al.   MOLECULAR AND CELLULAR BIOLOGY