Protein arginine methyltransferase 3 promotes glycolysis and hepatocellular carcinoma growth by enhancing arginine methylation of lactate dehydrogenase A

PRMT3 interacts with ALDH1A1 and regulates gene-expression by inhibiting retinoic acid signaling

(2021) Mamta Verma et al.   Communications Biology

Protein arginine methyltransferases and hepatocellular carcinoma: A review

(2021) Yu Lei et al.   Translational Oncology

Structural and functional regulation of lactate dehydrogenase-A in cancer

(2020) Mark R Woodford et al.   Future Medicinal Chemistry

Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinoma

(2020) Jiao Feng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

PRMT2 accelerates tumorigenesis of hepatocellular carcinoma by activating Bcl2 via histone H3R8 methylation

(2020) Guohui Hu et al.   EXPERIMENTAL CELL RESEARCH

Lysine-222 succinylation reduces lysosomal degradation of lactate dehydrogenase a and is increased in gastric cancer

(2020) Xiang Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Natural products and other inhibitors of F1FO ATP synthase

(2020) Bhargav A. Patel et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression

(2019) Russell E. Ericksen et al.   Cell Metabolism

Gluconeogenesis in cancer cells – Repurposing of a starvation-induced metabolic pathway?

(2019) Gabriele Grasmann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Protein arginine methyltransferase 3-induced metabolic reprogramming is a vulnerable target of pancreatic cancer

(2019) Ming-Chuan Hsu et al.   Journal of Hematology & Oncology

The regulation, functions and clinical relevance of arginine methylation

(2019) Ernesto Guccione et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The importance of non-histone protein methylation in cancer therapy

(2019) Manuel Rodríguez-Paredes et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PRMTs and Arginine Methylation: Cancer’s Best-Kept Secret?

(2019) James Jarrold et al.   TRENDS IN MOLECULAR MEDICINE

CRAF methylation by PRMT6 regulates aerobic glycolysis driven hepatocarcinogenesis via ERK‐dependent PKM2 nuclear relocalization and activation

(2019) Tin‐Lok Wong et al.   HEPATOLOGY

Asymmetrical methyltransferase PRMT3 regulates human mesenchymal stem cell osteogenesis via miR-3648

(2019) Zhang Min et al.   Cell Death & Disease

Inhibition of protein arginine methyltransferase 3 activity selectively impairs liver X receptor-driven transcription of hepatic lipogenic genes in vivo

(2018) Joya E Nahon et al.   BRITISH JOURNAL OF PHARMACOLOGY

PRMT1 negatively regulates activation-induced cell death in macrophages by arginine methylation of GAPDH

(2018) Jun-Ho Cho et al.   EXPERIMENTAL CELL RESEARCH

Role of gut microbiota and oxidative stress in the progression of non-alcoholic fatty liver disease to hepatocarcinoma: Current and innovative therapeutic approaches

(2018) Antonella Borrelli et al.   Redox Biology

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

CARM1 Methylates GAPDH to Regulate Glucose Metabolism and Is Suppressed in Liver Cancer

(2018) Xing-Yu Zhong et al.   Cell Reports

Arginine methylation of SIRT7 couples glucose sensing with mitochondria biogenesis

(2018) Wei‐Wei Yan et al.   EMBO REPORTS

Metabolic aspects in NAFLD, NASH and hepatocellular carcinoma: the role of PGC1 coactivators

(2018) Elena Piccinin et al.   Nature Reviews Gastroenterology & Hepatology

Functions and mechanisms of non-histone protein acetylation

(2018) Takeo Narita et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PRMT6 Regulates RAS/RAF Binding and MEK/ERK-Mediated Cancer Stemness Activities in Hepatocellular Carcinoma through CRAF Methylation

(2018) Lok Hei Chan et al.   Cell Reports

Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy

(2018) Yangbo Feng et al.   Cancer Medicine

Protein Arginine Methyltransferase 3 Enhances Chemoresistance in Pancreatic Cancer by Methylating hnRNPA1 to Increase ABCG2 Expression

(2018) Ming-Chuan Hsu et al.   Cancers

Phosphorylation-mediated activation of LDHA promotes cancer cell invasion and tumour metastasis

(2017) L Jin et al.   ONCOGENE

A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)

(2015) H. Ümit Kaniskan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Autophagy and Lipid Droplets in the Liver

(2015) Nuria Martinez-Lopez et al.   Annual Review of Nutrition

Physiology and pathophysiology of liver lipid metabolism

(2015) Francesca Romana Ponziani et al.   Expert Review of Gastroenterology & Hepatology

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Lysine-5 Acetylation Negatively Regulates Lactate Dehydrogenase A and Is Decreased in Pancreatic Cancer

(2013) Di Zhao et al.   CANCER CELL

Hepatic glucose sensing and integrative pathways in the liver

(2013) Maaike H. Oosterveer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cancer Epigenetics: From Mechanism to Therapy

(2012) Mark A. Dawson et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL

Promiscuous Modification of the Nuclear Poly(A)-binding Protein by Multiple Protein-arginine Methyltransferases Does Not Affect the Aggregation Behavior

(2008) Katharina Fronz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY