Bioinspired therapeutic platform based on extracellular vesicles for prevention of arterial wall remodeling in hypertension

The biology, function, and biomedical applications of exosomes

(2020) Raghu Kalluri et al.   SCIENCE

Classical and Nonclassical Intercellular Communication in Senescence and Ageing

(2020) Juan Antonio Fafián-Labora et al.   TRENDS IN CELL BIOLOGY

Dermal exosomes containing miR-218-5p promote hair regeneration by regulating β-catenin signaling

(2020) Shiqi Hu et al.   Science Advances

Smooth Muscle Contact Drives Endothelial Regeneration by BMPR2-Notch1–Mediated Metabolic and Epigenetic Changes

(2019) Kazuya Miyagawa et al.   CIRCULATION RESEARCH

Exosomal miR-423-5p mediates the proangiogenic activity of human adipose-derived stem cells by targeting Sufu

(2019) Fen Xu et al.   Stem Cell Research & Therapy

Atorvastatin Enhances the Therapeutic Efficacy of Mesenchymal Stem Cells Derived Exosomes in Acute Myocardial Infarction via Up-regulating Long Non-coding RNA H19

(2019) Peisen Huang et al.   CARDIOVASCULAR RESEARCH

Reassessment of Exosome Composition

(2019) Dennis K. Jeppesen et al.   CELL

MiR‐423‐5p inhibition alleviates cardiomyocyte apoptosis and mitochondrial dysfunction caused by hypoxia/reoxygenation through activation of the wnt/β‐catenin signaling pathway via targeting MYBL2

(2019) Xin Zhu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Compressive Force‐Induced Autophagy in Periodontal Ligament Cells Downregulates Osteoclastogenesis During Tooth Movement

(2019) Liyuan Chen et al.   JOURNAL OF PERIODONTOLOGY

Advances in therapeutic applications of extracellular vesicles

(2019) Oscar P. B. Wiklander et al.   Science Translational Medicine

Vascular Endothelial Cell Biology: An Update

(2019) Krüger-Genge et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Vicious Cycle of Arterial Stiffness and Arterial Media Calcification

(2019) Geoffrey Van den Bergh et al.   TRENDS IN MOLECULAR MEDICINE

Surface functionalized exosomes as targeted drug delivery vehicles for cerebral ischemia therapy

(2018) Tian Tian et al.   BIOMATERIALS

Activation of the non-canonical NF-κB/p52 pathway in vascular endothelial cells by RANKL elicits pro-calcific signalling in co-cultured smooth muscle cells

(2018) Emma Harper et al.   CELLULAR SIGNALLING

Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

(2018) Arnau Hervera et al.   NATURE CELL BIOLOGY

Anchor peptide captures, targets, and loads exosomes of diverse origins for diagnostics and therapy

(2018) Xianjun Gao et al.   Science Translational Medicine

The Exosome-Derived Biomarker in Atherosclerosis and Its Clinical Application

(2018) Mengmeng Lu et al.   Journal of Cardiovascular Translational Research

Hypertension

(2018) Suzanne Oparil et al.   Nature Reviews Disease Primers

Exosomes/microvesicles microRNA-423-3p derived from cardiac fibroblasts mediates the cardioprotective effects of ischemic postconditioning

(2018) Hui Luo et al.   CARDIOVASCULAR RESEARCH

Exosome-Mediated Transfer of ACE (Angiotensin-Converting Enzyme) From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promotes Vascular Smooth Muscle Cell Migration

(2018) Ying Tong et al.   HYPERTENSION

Exosome as a Novel Shuttle for Delivery of Therapeutics across Biological Barriers

(2018) Chandan Kanta Das et al.   MOLECULAR PHARMACEUTICS

Specificities of secretion and uptake of exosomes and other extracellular vesicles for cell-to-cell communication

(2018) Mathilde Mathieu et al.   NATURE CELL BIOLOGY

Prevalence, Treatment, and Control Rates of Conventional and Ambulatory Hypertension Across 10 Populations in 3 ContinentsNovelty and Significance

(2017) Jesus D. Melgarejo et al.   HYPERTENSION

Global Burden of Hypertension and Systolic Blood Pressure of at Least 110 to 115 mm Hg, 1990-2015

(2017) Mohammad H. Forouzanfar et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Exosome-Mediated miR-155 Transfer from Smooth Muscle Cells to Endothelial Cells Induces Endothelial Injury and Promotes Atherosclerosis

(2017) Bin Zheng et al.   MOLECULAR THERAPY

Arterial stiffness as a risk factor for clinical hypertension

(2017) Michel E. Safar   Nature Reviews Cardiology

Mechanical force-mediated pathological cartilage thinning is regulated by necroptosis and apoptosis

(2017) C. Zhang et al.   OSTEOARTHRITIS AND CARTILAGE

Valid gene expression normalization by RT-qPCR in studies on hPDL fibroblasts with focus on orthodontic tooth movement and periodontitis

(2017) Christian Kirschneck et al.   Scientific Reports

Global Disparities of Hypertension Prevalence and ControlClinical Perspective

(2016) Katherine T. Mills et al.   CIRCULATION

Vascular Smooth Muscle Cell Calcification Is Mediated by Regulated Exosome Secretion

(2015) A. N. Kapustin et al.   CIRCULATION RESEARCH

The Structural Factor of Hypertension: Large and Small Artery Alterations

(2015) S. Laurent et al.   CIRCULATION RESEARCH

MiR-320a contributes to atherogenesis by augmenting multiple risk factors and down-regulating SRF

(2015) Chen Chen et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Shear Stress–Initiated Signaling and Its Regulation of Endothelial Function

(2014) Jing Zhou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Exosomes

(2014) Derek M. Yellon et al.   CIRCULATION RESEARCH

Endothelial Dysfunction and Hypertension

(2014) Ralf P. Brandes   HYPERTENSION

Different modes of endothelial–smooth muscle cell interaction elicit differential β-catenin phosphorylations and endothelial functions

(2014) Shun-Fu Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanotransduction: Forces, Sensors, and Redox Signaling

(2013) Shampa Chatterjee et al.   ANTIOXIDANTS & REDOX SIGNALING

A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy

(2013) Yanhua Tian et al.   BIOMATERIALS

The atherosusceptible endothelium: endothelial phenotypes in complex haemodynamic shear stress regions in vivo

(2013) Peter F. Davies et al.   CARDIOVASCULAR RESEARCH

Modulation of microRNAs in hypertension-induced arterial remodeling through the β1 and β3-adrenoreceptor pathways

(2013) Shukuan Ling et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Role of Mechanical Force and ROS in Integrin-Dependent Signals

(2013) Kathrin S. Zeller et al.   PLoS One

Exosomes for targeted siRNA delivery across biological barriers

(2012) Samir EL Andaloussi et al.   ADVANCED DRUG DELIVERY REVIEWS

Extracellular vesicles in physiological and pathological conditions

(2012) Yuana Yuana et al.   BLOOD REVIEWS

Interleukin-17 causes Rho-kinase-mediated endothelial dysfunction and hypertension

(2012) Hoanglan Nguyen et al.   CARDIOVASCULAR RESEARCH

Transfer of extracellular vesicles during immune cell-cell interactions

(2012) Cristina Gutiérrez-Vázquez et al.   IMMUNOLOGICAL REVIEWS

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

(2012) Eduard Hergenreider et al.   NATURE CELL BIOLOGY

Asymmetric dimethylarginine confers the communication between endothelial and smooth muscle cells and leads to VSMC migration through p38 and ERK1/2 signaling cascade

(2011) Lan Sun et al.   FEBS LETTERS

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

Endothelial Dysfunction and the Risk of Hypertension

(2010) Daichi Shimbo et al.   HYPERTENSION

Endothelial Progenitor Cells, Endothelial Dysfunction, Inflammation, and Oxidative Stress in Hypertension

(2008) Timothy Watson et al.   ANTIOXIDANTS & REDOX SIGNALING