The Role of Mechanical Force and ROS in Integrin-Dependent Signals

β1 Integrins restrict the growth of foci and spheroids

(2012) Rajesh Kumar Gupta et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Tension is required but not sufficient for focal adhesion maturation without a stress fiber template

(2012) Patrick W. Oakes et al.   JOURNAL OF CELL BIOLOGY

Receptor-Specific Mechanisms Regulate Phosphorylation of AKT at Ser473: Role of RICTOR in β1 Integrin-Mediated Cell Survival

(2012) Anjum Riaz et al.   PLoS One

Reactive Oxygen Species Regulate Protrusion Efficiency by Controlling Actin Dynamics

(2012) Nicolas Taulet et al.   PLoS One

Comparing mechano-transduction in fibroblasts deficient of focal adhesion proteins

(2011) Tuli Dey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Unraveling the Biological Roles of Reactive Oxygen Species

(2011) Michael P. Murphy et al.   Cell Metabolism

Integrin inside-out signaling and the immunological synapse

(2011) Timothy A Springer et al.   CURRENT OPINION IN CELL BIOLOGY

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

(2011) Christophe Guilluy et al.   NATURE CELL BIOLOGY

Fluorescent Protein-Based Redox Probes

(2010) Andreas J. Meyer et al.   ANTIOXIDANTS & REDOX SIGNALING

Mechanical Strain-Induced RhoA Activation Requires NADPH Oxidase-Mediated ROS Generation in Caveolae

(2010) Ying Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

What does the commonly used DCF test for oxidative stress really show?

(2010) Markus Karlsson et al.   BIOCHEMICAL JOURNAL

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

PI3-kinase p110α mediates β1 integrin-induced Akt activation and membrane protrusion during cell attachment and initial spreading

(2010) Kathrin S. Zeller et al.   CELLULAR SIGNALLING

Stretchy Proteins on Stretchy Substrates: The Important Elements of Integrin-Mediated Rigidity Sensing

(2010) Simon W. Moore et al.   DEVELOPMENTAL CELL

Stretch-Induced Stress Fiber Remodeling and the Activations of JNK and ERK Depend on Mechanical Strain Rate, but Not FAK

(2010) Hui-Ju Hsu et al.   PLoS One

The Akt isoforms are present at distinct subcellular locations

(2009) Stacey A. Santi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Keeping the intracellular vitamin C at a physiologically relevant level in endothelial cell culture

(2009) Henriette Frikke-Schmidt et al.   ANALYTICAL BIOCHEMISTRY

The cofilin activity cycle in lamellipodia and invadopodia

(2009) Matthew Oser et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Reactive Oxygen Species Regulate a Slingshot-Cofilin Activation Pathway

(2009) Jun-Sub Kim et al.   MOLECULAR BIOLOGY OF THE CELL

A genetically encoded fluorescent reporter of ATP:ADP ratio

(2009) Jim Berg et al.   NATURE METHODS

Direct Activation of RhoA by Reactive Oxygen Species Requires a Redox-Sensitive Motif

(2009) Amir Aghajanian et al.   PLoS One

Mechanically Activated Integrin Switch Controls  5 1 Function

(2009) J. C. Friedland et al.   SCIENCE

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Oxidation of Cofilin Mediates T Cell Hyporesponsiveness under Oxidative Stress Conditions

(2008) Martin Klemke et al.   IMMUNITY

Mechanotransduction - a field pulling together?

(2008) C. S. Chen   JOURNAL OF CELL SCIENCE

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

(2008) Ning Wang et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY