Positive Selection Drives the Adaptive Evolution of Mitochondrial Antiviral Signaling (MAVS) Proteins-Mediating Innate Immunity in Mammals

TRK-Fused Gene (TFG), a protein involved in protein secretion pathways, is an essential component of the antiviral innate immune response

(2021) Kashif Aziz Khan et al.   PLoS Pathogens

Mitochondrial reactive zones in antiviral innate immunity

(2021) Kai Yasukawa et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

In Silico Structural, Functional, and Phylogenetic Analysis of Cytochrome (CYPD) Protein Family

(2021) Hafiz Ishfaq Ahmad et al.   Biomed Research International

Porcine RIG-I and MDA5 Signaling CARD Domains Exert Similar Antiviral Function Against Different Viruses

(2021) Shuangjie Li et al.   Frontiers in Microbiology

Repeated MDA5 Gene Loss in Birds: An Evolutionary Perspective

(2021) Veronika Krchlíková et al.   Viruses-Basel

Adaptive selection in the evolution of programmed cell death-1 and its ligands in vertebrates

(2020) Hafiz Ishfaq Ahmad et al.   Aging-US

Immune Response Dysfunction in Chronic Lymphocytic Leukemia: Dissecting Molecular Mechanisms and Microenvironmental Conditions

(2020) Francesca Arruga et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Innate and Adaptive Immune Responses Against Microsporidia Infection in Mammals

(2020) Yinze Han et al.   Frontiers in Microbiology

Adaptive evolution of peptidoglycan recognition protein family regulates the innate signaling against microbial pathogens in vertebrates

(2020) Hafiz Ishfaq Ahmad et al.   MICROBIAL PATHOGENESIS

Innate-adaptive immunity interplay and redox regulation in immune response

(2020) Lizhe Sun et al.   Redox Biology

An Extension of the Kimura Two-Parameter Model to the Natural Evolutionary Process

(2019) Takuma Nishimaki et al.   JOURNAL OF MOLECULAR EVOLUTION

Mitochondria: the indispensable players in innate immunity and guardians of the inflammatory response

(2019) Abhishek Mohanty et al.   Journal of Cell Communication and Signaling

BEAGLE 3: Improved Performance, Scaling, and Usability for a High-Performance Computing Library for Statistical Phylogenetics

(2019) Daniel L Ayres et al.   SYSTEMATIC BIOLOGY

Genomic analysis and adaptive evolution of the RIG-I-like and NOD-like receptors in reptiles

(2019) Jun Chen et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

KEGG Mapper for inferring cellular functions from protein sequences

(2019) Minoru Kanehisa et al.   PROTEIN SCIENCE

On the Use of Information Criteria for Model Selection in Phylogenetics

(2019) Edward Susko et al.   MOLECULAR BIOLOGY AND EVOLUTION

Oligomerization of RIG‐I and MDA5 2CARD domains

(2019) Cassie M. Zerbe et al.   PROTEIN SCIENCE

ConSurf‐DB: An accessible repository for the evolutionary conservation patterns of the majority of PDB proteins

(2019) Adi Ben Chorin et al.   PROTEIN SCIENCE

Genetic variation and relationships in the mitochondrial DNA D-loop region of Qinghai indigenous and commercial pig breeds

(2018) Junxia Zhang et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

The advantage of recombination when selection is acting at many genetic Loci

(2018) Donal A. Hickey et al.   JOURNAL OF THEORETICAL BIOLOGY

Datamonkey 2.0: A Modern Web Application for Characterizing Selective and Other Evolutionary Processes

(2018) Steven Weaver et al.   MOLECULAR BIOLOGY AND EVOLUTION

Positive selection drives the evolution of endocrine regulatory bone morphogenetic protein system in mammals

(2018) Hafiz Ishfaq Ahmad et al.   Oncotarget

Maximum-likelihood approaches reveal signatures of positive selection in BMP15 and GDF9 genes modulating ovarian function in mammalian female fertility

(2017) Hafiz Ishfaq Ahmad et al.   Ecology and Evolution

Positive selection of IL-33 in adaptive immunity of domestic Chinese goats

(2017) Akhtar Rasool Asif et al.   Ecology and Evolution

The Phyre2 web portal for protein modeling, prediction and analysis

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A Simple Method for Estimating the Strength of Natural Selection on Overlapping Genes

(2015) Xinzhu Wei et al.   Genome Biology and Evolution

Mitochondrial dynamics and the innate antiviral immune response

(2014) Marie Pourcelot et al.   FEBS Journal

Positive Selection and Multiple Losses of the LINE-1-Derived L1TD1 Gene in Mammals Suggest a Dual Role in Genome Defense and Pluripotency

(2014) Richard N. McLaughlin et al.   PLoS Genetics

ConSurf: Using Evolutionary Data to Raise Testable Hypotheses about Protein Function

(2013) Gershon Celniker et al.   ISRAEL JOURNAL OF CHEMISTRY

Mechanisms of MAVS Regulation at the Mitochondrial Membrane

(2013) Jana L. Jacobs et al.   JOURNAL OF MOLECULAR BIOLOGY

MEGA6: Molecular Evolutionary Genetics Analysis Version 6.0

(2013) Koichiro Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Mitochondrial-mediated antiviral immunity

(2012) Takumi Koshiba   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

EnrichNet: network-based gene set enrichment analysis

(2012) Enrico Glaab et al.   BIOINFORMATICS

Convergent Evolution of Escape from Hepaciviral Antagonism in Primates

(2012) Maulik R. Patel et al.   PLOS BIOLOGY

Orchestrating the interferon antiviral response through the mitochondrial antiviral signaling (MAVS) adapter

(2011) S Mehdi Belgnaoui et al.   CURRENT OPINION IN IMMUNOLOGY

Analysing recombination in nucleotide sequences

(2011) DARREN P. MARTIN et al.   Molecular Ecology Resources

Mitochondrial antiviral signaling protein (MAVS) monitors commensal bacteria and induces an immune response that prevents experimental colitis

(2011) X.-D. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of mitochondria in the mammalian antiviral defense system

(2010) Iain Scott   MITOCHONDRION

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One

Toll-like Receptor and RIG-1-like Receptor Signaling

(2009) Taro Kawai et al.   Annals of the New York Academy of Sciences

Proteomics enhances evolutionary and functional analysis of reproductive proteins

(2009) Geoffrey D. Findlay et al.   BIOESSAYS

Mitochondrial Antiviral Signaling Protein Plays a Major Role in Induction of the Fish Innate Immune Response against RNA and DNA Viruses

(2009) S. Biacchesi et al.   JOURNAL OF VIROLOGY

The microbial and danger signals that activate Nod-like receptors

(2008) Szilvia Benko et al.   CYTOKINE

Protein kinase R reveals an evolutionary model for defeating viral mimicry

(2008) Nels C. Elde et al.   NATURE