Oligomerization of RIG‐I and MDA5 2CARD domains

Assembly mechanism of the CARMA1–BCL10–MALT1–TRAF6 signalosome

(2018) Liron David et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis

(2018) Qin Yu et al.   MOLECULAR CELL

Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1

(2018) Yang Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis of RIP2 activation and signaling

(2018) Qin Gong et al.   Nature Communications

Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling

(2017) Peng Tan et al.   MOLECULAR CELL

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism

(2016) Alvin Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism

(2016) Alvin Lu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

How RIG-I like receptors activate MAVS

(2015) Bin Wu et al.   Current Opinion in Virology

Molecular Imprinting as a Signal-Activation Mechanism of the Viral RNA Sensor RIG-I

(2014) Bin Wu et al.   MOLECULAR CELL

Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I

(2014) Alys Peisley et al.   NATURE

Defining the functional determinants for RNA surveillance by RIG-I

(2013) Andrew Kohlway et al.   EMBO REPORTS

RIG-I Forms Signaling-Competent Filaments in an ATP-Dependent, Ubiquitin-Independent Manner

(2013) Alys Peisley et al.   MOLECULAR CELL

Structural Basis for dsRNA Recognition, Filament Formation, and Antiviral Signal Activation by MDA5

(2012) Bin Wu et al.   CELL

Helical assembly in the death domain (DD) superfamily

(2012) Ryan Ferrao et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA

(2012) Ian C Berke et al.   EMBO JOURNAL

Ubiquitin-Induced Oligomerization of the RNA Sensors RIG-I and MDA5 Activates Antiviral Innate Immune Response

(2012) Xiaomo Jiang et al.   IMMUNITY

The Thermodynamic Basis for Viral RNA Detection by the RIG-I Innate Immune Sensor

(2012) Adriana Vela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MDA5 assembles into a polar helical filament on dsRNA

(2012) I. C. Berke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A structure-based model of RIG-I activation

(2012) D. Kolakofsky et al.   RNA

Structural Basis for the Activation of Innate Immune Pattern-Recognition Receptor RIG-I by Viral RNA

(2011) Eva Kowalinski et al.   CELL

MAVS Forms Functional Prion-like Aggregates to Activate and Propagate Antiviral Innate Immune Response

(2011) Fajian Hou et al.   CELL

Evaluating the stoichiometry of macromolecular complexes using multisignal sedimentation velocity

(2011) Shae B. Padrick et al.   METHODS

Cooperative assembly and dynamic disassembly of MDA5 filaments for viral dsRNA recognition

(2011) A. Peisley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preparation of Distinct Ubiquitin Chain Reagents of High Purity and Yield

(2011) Ken C. Dong et al.   STRUCTURE

Preference of RIG-I for short viral RNA molecules in infected cells revealed by next-generation sequencing

(2010) A. Baum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structural Basis of 5′ Triphosphate Double-Stranded RNA Recognition by RIG-I C-Terminal Domain

(2010) Cheng Lu et al.   STRUCTURE