Targeting Mechanosensitive Piezo1 Alleviated Renal Fibrosis Through p38MAPK-YAP Pathway

Oxidative stress activates the Nrf2-mediated antioxidant response and P38 MAPK pathway: a possible apoptotic mechanism induced by BDE-47 in rainbow trout (Oncorhynchus mykiss) gonadal RTG-2 cells

(2021) Zhongyuan Zhou et al.   ENVIRONMENTAL POLLUTION

Substratum stiffness tunes membrane voltage in mammary epithelial cells

(2021) Brian B. Silver et al.   JOURNAL OF CELL SCIENCE

Axl‐inhibitor bemcentinib alleviates mitochondrial dysfunction in the unilateral ureter obstruction murine model

(2021) August Hoel et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechanoregulation of YAP and TAZ in Cellular Homeostasis and Disease Progression

(2021) Xiaomin Cai et al.   Frontiers in Cell and Developmental Biology

Targeting MAPK Signaling in Cancer: Mechanisms of Drug Resistance and Sensitivity

(2020) Shannon Lee et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk

(2020) Lijun Wang et al.   Nature Communications

Dysfunctional Mechanotransduction through the YAP/TAZ/Hippo Pathway as a Feature of Chronic Disease

(2020) Mathias Cobbaut et al.   Cells

Tissue stiffness contributes to YAP activation in bladder cancer patients undergoing transurethral resection

(2020) Hadi Ghasemi et al.   Annals of the New York Academy of Sciences

Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling

(2020) Yoshito Yamashiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Crosstalk between Src and Hippo/YAP Signaling Pathways in Non-Small Cell Lung Cancer (NSCLC)

(2020) Ping-Chih Hsu et al.   Cancers

Infarct Collagen Topography Regulates Fibroblast Fate via p38-Yes-Associated Protein Transcriptional Enhanced Associate Domain Signals

(2020) Darrian Bugg et al.   CIRCULATION RESEARCH

YAP signaling induces PIEZO1 to promote oral squamous cell carcinoma cell proliferation

(2020) Kana Hasegawa et al.   JOURNAL OF PATHOLOGY

Piezo1-Mediated Ca2+ Activities Regulate Brain Vascular Pathfinding during Development

(2020) Ting-ting Liu et al.   NEURON

Mechanical and Physical Regulation of Fibroblast–Myofibroblast Transition: From Cellular Mechanoresponse to Tissue Pathology

(2020) Mirko D'Urso et al.   Frontiers in Bioengineering and Biotechnology

Piezo1 mediates neuron oxygen-glucose deprivation/reoxygenation injury via Ca2+/calpain signaling

(2019) Ying-Ying Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

YAP-independent mechanotransduction drives breast cancer progression

(2019) Joanna Y. Lee et al.   Nature Communications

PIEZO1 and TRPV4, which Are Distinct Mechano-Sensors in the Osteoblastic MC3T3-E1 Cells, Modify Cell-Proliferation

(2019) Maki Yoneda et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion

(2019) Nicola M. Blythe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Control of cellular responses to mechanical cues through YAP/TAZ regulation

(2019) Ishani Dasgupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Author Correction: Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity

(2019) Angel G. Solis et al.   NATURE

Targeting downstream subcellular YAP activity as a function of matrix stiffness with Verteporfin-encapsulated chitosan microsphere attenuates osteoarthritis

(2019) Xianzhu Zhang et al.   BIOMATERIALS

Author Correction: Regulation of Hippo pathway transcription factor TEAD by p38 MAPK-induced cytoplasmic translocation

(2018) Kimberly C. Lin et al.   NATURE CELL BIOLOGY

Renal compartment–specific genetic variation analyses identify new pathways in chronic kidney disease

(2018) Chengxiang Qiu et al.   NATURE MEDICINE

YAP/TAZ Signaling as a Molecular Link between Fibrosis and Cancer

(2018) Satoshi Noguchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Biomaterials and engineered microenvironments to control YAP/TAZ-dependent cell behaviour

(2018) Giovanna Brusatin et al.   NATURE MATERIALS

A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression

(2018) Xin Chen et al.   NEURON

Ribes diacanthum Pall (RDP) ameliorates UUO-induced renal fibrosis via both canonical and non-canonical TGF-β signaling pathways in mice

(2018) Lifei Gu et al.   JOURNAL OF ETHNOPHARMACOLOGY

C-type natriuretic peptide suppresses mesangial proliferation and matrix expression via a MMPs/TIMPs-independent pathway in vitro

(2017) Bao Yu Huang et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Yap/Taz Deletion in Gli+Cell-Derived Myofibroblasts Attenuates Fibrosis

(2017) Ming Liang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Crosstalk Influence between P38MAPK and Autophagy on Mitochondria-Mediated Apoptosis Induced by Anti-Fas Antibody/Actinomycin D in Human Hepatoma Bel-7402 Cells

(2017) Yu Wang et al.   MOLECULES

Mechanobiology of YAP and TAZ in physiology and disease

(2017) Tito Panciera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanical forces direct stem cell behaviour in development and regeneration

(2017) Kyle H. Vining et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Piezo1 Channels Are Inherently Mechanosensitive

(2016) Ruhma Syeda et al.   Cell Reports

Anti-pulmonary fibrotic activity of salvianolic acid B was screened by a novel method based on the cyto-biophysical properties

(2015) Miao Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex

(2014) Wenjing Zhang et al.   CELL RESEARCH

Nanoscale distribution of CD20 on B-cell lymphoma tumour cells and its potential role in the clinical efficacy of rituximab

(2014) M. LI et al.   JOURNAL OF MICROSCOPY

Nanoscale Imaging and Mechanical Analysis of Fc Receptor-Mediated Macrophage Phagocytosis against Cancer Cells

(2014) Mi Li et al.   LANGMUIR

Piezo1 integration of vascular architecture with physiological force

(2014) Jing Li et al.   NATURE

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE