Tissue stiffness contributes to YAP activation in bladder cancer patients undergoing transurethral resection

Collagen stiffness promoted non-muscle-invasive bladder cancer progression to muscle-invasive bladder cancer

(2019) Huier Zhu et al.   OncoTargets and Therapy

Inhibition of SDC4-LOX mediated extracellular matrix stiffening prevents chondrocyte differentiation in OA cartilage via increased YAP/TAZ signaling

(2019) A. Held et al.   OSTEOARTHRITIS AND CARTILAGE

Evolution of mechanotransduction via YAP/TAZ in animal epithelia

(2018) Ahmed Elbediwy et al.   CURRENT OPINION IN CELL BIOLOGY

Crosstalk between Nrf2 and YAP contributes to maintaining the antioxidant potential and chemoresistance in bladder cancer

(2018) Eric Ciamporcero et al.   FREE RADICAL BIOLOGY AND MEDICINE

Actin like-6A promotes glioma progression through stabilization of transcriptional regulators YAP/TAZ

(2018) Jianxiong Ji et al.   Cell Death & Disease

Lysyl oxidase: A colorectal cancer biomarker of lung and hepatic metastasis

(2018) Yun Liu et al.   Thoracic Cancer

Linking Extracellular Matrix Agrin to the Hippo Pathway in Liver Cancer and Beyond

(2018) Sayan Chakraborty et al.   Cancers

YAP/TAZ Signaling as a Molecular Link between Fibrosis and Cancer

(2018) Satoshi Noguchi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Human colorectal cancer progression correlates with LOX-induced ECM stiffening

(2017) Bo Wei et al.   International Journal of Biological Sciences

Mechanobiology of YAP and TAZ in physiology and disease

(2017) Tito Panciera et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ

(2017) A Noto et al.   ONCOGENE

Agrin as a Mechanotransduction Signal Regulating YAP through the Hippo Pathway

(2017) Sayan Chakraborty et al.   Cell Reports

Bladder cancer

(2017) Oner Sanli et al.   Nature Reviews Disease Primers

Tissue elasticity properties as biomarkers for prostate cancer

(2017) Kenneth Hoyt et al.   Cancer Biomarkers

Systematic Review and Individual Patient Data Meta-analysis of Randomized Trials Comparing a Single Immediate Instillation of Chemotherapy After Transurethral Resection with Transurethral Resection Alone in Patients with Stage pTa–pT1 Urothelial Carcinoma of the Bladder: Which Patients Benefit from the Instillation?

(2016) Richard J. Sylvester et al.   EUROPEAN UROLOGY

The 2016 WHO Classification of Tumours of the Urinary System and Male Genital Organs—Part B: Prostate and Bladder Tumours

(2016) Peter A. Humphrey et al.   EUROPEAN UROLOGY

Mechanosensing in cell–matrix adhesions – Converting tension into chemical signals

(2016) Vesa P. Hytönen et al.   EXPERIMENTAL CELL RESEARCH

Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction

(2016) Sirio Dupont   EXPERIMENTAL CELL RESEARCH

Mechanisms of Hippo pathway regulation

(2016) Zhipeng Meng et al.   GENES & DEVELOPMENT

Positive association of collagen type I with non-muscle invasive bladder cancer progression

(2016) Michael Brooks et al.   Oncotarget

Mechanotransduction in cancer

(2016) LiKang Chin et al.   Current Opinion in Chemical Engineering

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

Stiffness of cancer cells measured with an AFM indentation method

(2015) Kozaburo Hayashi et al.   Journal of the Mechanical Behavior of Biomedical Materials

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

(2015) Spencer C. Wei et al.   NATURE CELL BIOLOGY

YAP Regulates S-Phase Entry in Endothelial Cells

(2015) Zhewei Shen et al.   PLoS One

Metastatic breast cancer cells in lymph nodes increase nodal collagen density

(2015) Asif Rizwan et al.   Scientific Reports

Mechanism of regulation of stem cell differentiation by matrix stiffness

(2015) Hongwei Lv et al.   Stem Cell Research & Therapy

Extracellular Matrix Reorganization During Wound Healing and Its Impact on Abnormal Scarring

(2015) Meilang Xue et al.   Advances in Wound Care

Lysyl Oxidase Contributes to Mechanotransduction-Mediated Regulation of Transforming Growth Factor-β Signaling in Breast Cancer Cells

(2015) Molly A. Taylor et al.   NEOPLASIA

Mechanotransduction at focal adhesions: from physiology to cancer development

(2013) Jihye Seong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts

(2013) Fernando Calvo et al.   NATURE CELL BIOLOGY

Increased Collagen Synthesis Rate during Wound Healing in Muscle

(2013) Shaobo Zhou et al.   PLoS One

Epidemiology and Risk Factors of Urothelial Bladder Cancer

(2012) Maximilian Burger et al.   EUROPEAN UROLOGY

Cancer cell detection in tissue sections using AFM

(2011) Małgorzata Lekka et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Biomechanical Remodeling of the Microenvironment by Stromal Caveolin-1 Favors Tumor Invasion and Metastasis

(2011) Jacky G. Goetz et al.   CELL

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Serum endostatin levels correlate with enhanced extracellular matrix degradation and poor patients' prognosis in bladder cancer

(2011) Tibor Szarvas et al.   INTERNATIONAL JOURNAL OF CANCER

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity

(2011) J. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of yes-associated protein contributes to progression and poor prognosis of non-small-cell lung cancer

(2010) Yang Wang et al.   CANCER SCIENCE

A Stiff Blow from the Stroma: Collagen Crosslinking Drives Tumor Progression

(2009) Mei Rosa Ng et al.   CANCER CELL

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Acute Wounds Accelerate Tumorigenesis by a T Cell-Dependent Mechanism

(2008) C. H. Stuelten et al.   CANCER RESEARCH

Integrins in prostate cancer progression

(2008) H. L. Goel et al.   ENDOCRINE-RELATED CANCER

A Single Instillation of Epirubicin After Transurethral Resection of Bladder Tumors Prevents Only Small Recurrences

(2007) Ingela Berrum-Svennung et al.   JOURNAL OF UROLOGY