Bifidobacterium species associated with breastfeeding produce aromatic lactic acids in the infant gut

Indole-3-lactic acid, a metabolite of tryptophan, secreted by Bifidobacterium longum subspecies infantis is anti-inflammatory in the immature intestine

(2020) Di Meng et al.   PEDIATRIC RESEARCH

Distinct immune phenotypes in infants developing asthma during childhood

(2020) Anna Hammerich Thysen et al.   Science Translational Medicine

Indole-3-lactic acid associated with Bifidobacterium-dominated microbiota significantly decreases inflammation in intestinal epithelial cells

(2020) Amy M. Ehrlich et al.   BMC MICROBIOLOGY

Role of the microbiome in human development

(2019) Maria Gloria Dominguez-Bello et al.   GUT

Novel insights from uncultivated genomes of the global human gut microbiome

(2019) Stephen Nayfach et al.   NATURE

Metabolites of lactic acid bacteria present in fermented foods are highly potent agonists of human hydroxycarboxylic acid receptor 3

(2019) Anna Peters et al.   PLoS Genetics

IFN-I and IL-22 mediate protective effects of intestinal viral infection

(2019) Jessica A Neil et al.   Nature Microbiology

Evolutionary adaptation in fucosyllactose uptake systems supports bifidobacteria-infant symbiosis

(2019) Mikiyasu Sakanaka et al.   Science Advances

Production of Indole-3-Lactic Acid by Bifidobacterium Strains Isolated fromHuman Infants

(2019) Takuma Sakurai et al.   Microorganisms

Glyphosate has limited short-term effects on commensal bacterial community composition in the gut environment due to sufficient aromatic amino acid levels

(2018) Lene Nørby Nielsen et al.   ENVIRONMENTAL POLLUTION

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

(2018) Lesley Hoyles et al.   NATURE MEDICINE

Maturation of the gut microbiome and risk of asthma in childhood

(2018) Jakob Stokholm et al.   Nature Communications

Intestinal microbiota development and gestational age in preterm neonates

(2018) Katri Korpela et al.   Scientific Reports

Gut Microbiota-Derived Tryptophan Metabolites Modulate Inflammatory Response in Hepatocytes and Macrophages

(2018) Smitha Krishnan et al.   Cell Reports

Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome

(2018) Jane M. Natividad et al.   Cell Metabolism

The Environmental Sensor AHR Protects from Inflammatory Damage by Maintaining Intestinal Stem Cell Homeostasis and Barrier Integrity

(2018) Amina Metidji et al.   IMMUNITY

Microbial tryptophan catabolites in health and disease

(2018) Henrik M. Roager et al.   Nature Communications

The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

(2018) Tommi Vatanen et al.   NATURE

Temporal development of the gut microbiome in early childhood from the TEDDY study

(2018) Christopher J. Stewart et al.   NATURE

Antibacterial activity of phenyllactic acid against Listeria monocytogenes and Escherichia coli by dual mechanisms

(2017) Yawei Ning et al.   FOOD CHEMISTRY

Human milk oligosaccharides and infant gut bifidobacteria: Molecular strategies for their utilization

(2017) Pamela Thomson et al.   FOOD MICROBIOLOGY

Gas chromatography – mass spectrometry data processing made easy

(2017) Lea G. Johnsen et al.   JOURNAL OF CHROMATOGRAPHY A

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

(2017) Dylan Dodd et al.   NATURE

Salt-responsive gut commensal modulates TH17 axis and disease

(2017) Nicola Wilck et al.   NATURE

Longitudinal change of selected human milk oligosaccharides and association to infants’ growth, an observatory, single center, longitudinal cohort study

(2017) Norbert Sprenger et al.   PLoS One

Lactobacillus reuteriinduces gut intraepithelial CD4+CD8αα+T cells

(2017) Luisa Cervantes-Barragan et al.   SCIENCE

Hydroxy-Carboxylic Acid Receptor Actions in Metabolism

(2017) Stefan Offermanns   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Genomic GC-Content Affects the Accuracy of 16S rRNA Gene Sequencing Based Microbial Profiling due to PCR Bias

(2017) Martin F. Laursen et al.   Frontiers in Microbiology

Differentiation of Bifidobacterium longum subspecies longum and infantis by quantitative PCR using functional gene targets

(2017) Blair Lawley et al.   PeerJ

Persistence of Supplemented Bifidobacterium longum subsp. infantis EVC001 in Breastfed Infants

(2017) Steven A. Frese et al.   mSphere

Host-derived glycans serve as selected nutrients for the gut microbe: human milk oligosaccharides and bifidobacteria

(2016) Takane Katayama   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Absolute Quantitation of Human Milk Oligosaccharides Reveals Phenotypic Variations during Lactation

(2016) Gege Xu et al.   JOURNAL OF NUTRITION

Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect

(2016) Cesar G Victora et al.   LANCET

CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

(2016) Bruno Lamas et al.   NATURE MEDICINE

Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation

(2016) Kei E Fujimura et al.   NATURE MEDICINE

The microbiome in early life: implications for health outcomes

(2016) Sabrina Tamburini et al.   NATURE MEDICINE

DADA2: High-resolution sample inference from Illumina amplicon data

(2016) Benjamin J Callahan et al.   NATURE METHODS

Age-associated effect of kestose on Faecalibacterium prausnitzii and symptoms in the atopic dermatitis infants

(2016) Yasuhiro Koga et al.   PEDIATRIC RESEARCH

The maternal microbiota drives early postnatal innate immune development

(2016) M. Gomez de Aguero et al.   SCIENCE

How colonization by microbiota in early life shapes the immune system

(2016) Thomas Gensollen et al.   SCIENCE

Colonic transit time is related to bacterial metabolism and mucosal turnover in the gut

(2016) Henrik M. Roager et al.   Nature Microbiology

Infant Gut Microbiota Development Is Driven by Transition to Family Foods Independent of Maternal Obesity

(2016) Martin Frederik Laursen et al.   mSphere

Long-term consequences of breastfeeding on cholesterol, obesity, systolic blood pressure and type 2 diabetes: a systematic review and meta-analysis

(2015) Bernardo L. Horta et al.   ACTA PAEDIATRICA

Metabolic footprinting for investigation of antifungal properties of Lactobacillus paracasei

(2015) Anders H. Honoré et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Having older siblings is associated with gut microbiota development during early childhood

(2015) Martin Frederik Laursen et al.   BMC MICROBIOLOGY

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life

(2015) Fredrik Bäckhed et al.   Cell Host & Microbe

The functional biology of human milk oligosaccharides

(2015) Lars Bode   EARLY HUMAN DEVELOPMENT

Innate Lymphoid Cells Control Early Colonization Resistance against Intestinal Pathogens through ID2-Dependent Regulation of the Microbiota

(2015) Xiaohuan Guo et al.   IMMUNITY

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

(2015) Troy D. Hubbard et al.   Scientific Reports

Functional analysis of bifidobacterial promoters in Bifidobacterium longum and Escherichia coli using the α-galactosidase gene as a reporter

(2014) Mikiyasu Sakanaka et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Are Structural Analogues to Bisphenol A Safe Alternatives?

(2014) Anna Kjerstine Rosenmai et al.   TOXICOLOGICAL SCIENCES

Disruption of the gut microbiome as a risk factor for microbial infections

(2013) Arya Khosravi et al.   CURRENT OPINION IN MICROBIOLOGY

Tryptophan Catabolites from Microbiota Engage Aryl Hydrocarbon Receptor and Balance Mucosal Reactivity via Interleukin-22

(2013) Teresa Zelante et al.   IMMUNITY

Lacto-N-biosidase Encoded by a Novel Gene ofBifidobacterium longumSubspecieslongumShows Unique Substrate Specificity and Requires a Designated Chaperone for Its Active Expression

(2013) Haruko Sakurama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

UPARSE: highly accurate OTU sequences from microbial amplicon reads

(2013) Robert C Edgar   NATURE METHODS

Bacterial Diversity in Meconium of Preterm Neonates and Evolution of Their Fecal Microbiota during the First Month of Life

(2013) Laura Moles et al.   PLoS One

IL-22 Mediates Goblet Cell Hyperplasia and Worm Expulsion in Intestinal Helminth Infection

(2013) Jan-Eric Turner et al.   PLoS Pathogens

Metabolic fingerprinting of high-fat plasma samples processed by centrifugation- and filtration-based protein precipitation delineates significant differences in metabolite information coverage

(2012) Thaer Barri et al.   ANALYTICA CHIMICA ACTA

Development of a Double-Crossover Markerless Gene Deletion System in Bifidobacterium longum: Functional Analysis of the α-Galactosidase Gene for Raffinose Assimilation

(2012) Yosuke Hirayama et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Establishment and development of intestinal microbiota in preterm neonates

(2011) Silvia Arboleya et al.   FEMS MICROBIOLOGY ECOLOGY

Antimicrobial activity of d-3-phenyllactic acid produced by fed-batch process against Salmonella enterica

(2011) Noelia Rodríguez et al.   FOOD CONTROL

IGF-I and IGFBP-3 in healthy 9month old infants from the SKOT cohort: Breastfeeding, diet, and later obesity

(2011) Anja L. Madsen et al.   GROWTH HORMONE & IGF RESEARCH

The Aryl Hydrocarbon Receptor Regulates Gut Immunity through Modulation of Innate Lymphoid Cells

(2011) Ju Qiu et al.   IMMUNITY

Bifidobacteria can protect from enteropathogenic infection through production of acetate

(2011) Shinji Fukuda et al.   NATURE

Natural Aryl Hydrocarbon Receptor Ligands Control Organogenesis of Intestinal Lymphoid Follicles

(2011) E. A. Kiss et al.   SCIENCE

MZmine 2: Modular framework for processing, visualizing, and analyzing mass spectrometry-based molecular profile data

(2010) Tomáš Pluskal et al.   BMC BIOINFORMATICS

Determinants of blood glucose and insulin in healthy 9-month-old term Danish infants; the SKOT cohort

(2010) A. L. Madsen et al.   DIABETIC MEDICINE

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Analytical platform for metabolome analysis of microbial cells using methyl chloroformate derivatization followed by gas chromatography–mass spectrometry

(2010) Kathleen F Smart et al.   Nature Protocols

Deorphanization of GPR109B as a Receptor for the β-Oxidation Intermediate 3-OH-octanoic Acid and Its Role in the Regulation of Lipolysis

(2009) Kashan Ahmed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analytical Error Reduction Using Single Point Calibration for Accurate and Precise Metabolomic Phenotyping

(2009) Frans M. van der Kloet et al.   JOURNAL OF PROTEOME RESEARCH

Aromatic D-amino acids act as chemoattractant factors for human leukocytes through a G protein-coupled receptor, GPR109B

(2009) Y. Irukayama-Tomobe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Purification and Partial Characterization ofLactobacillusSpecies SK007 Lactate Dehydrogenase (LDH) Catalyzing Phenylpyruvic Acid (PPA) Conversion into Phenyllactic Acid (PLA)

(2008) Xingfeng Li et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

(2008) Marc Veldhoen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

Control of Treg and TH17 cell differentiation by the aryl hydrocarbon receptor

(2008) Francisco J. Quintana et al.   NATURE

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

(2008) Yan Zheng et al.   NATURE MEDICINE