Iron-catalyzed decarboxylative and oxidative decarbonylative cross-coupling: a new strategy for the synthesis of monofluoroalkenes

Rhodium Catalyzed Regioselective C−H Allylation of Simple Arenes via C−C Bond Activation of Gem‐difluorinated Cyclopropanes

(2021) Zhong-Tao Jiang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron‐catalyzed oxidative decabonylation/radical cyclization of aliphatic aldehydes with biphenyl isocyanides: A new pathway for the synthesis of 6‐alkylphenanthridines

(2021) zaigang luo et al.   Asian Journal of Organic Chemistry

Dual Nickel/Ruthenium Strategy for Photoinduced Decarboxylative Cross-Coupling of α,β-Unsaturated Carboxylic Acids with Cycloketone Oxime Esters

(2021) Xiao-Yu Lu et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Dialkyl-Substituted Monofluoroalkenes via Palladium-Catalyzed Cross-Coupling of Alkyl Carbagermatranes

(2021) Chao Wang et al.   ORGANIC LETTERS

Iron‐Catalyzed Cleavage Reaction of Keto Acids with Aliphatic Aldehydes for the Synthesis of Ketones and Ketone Esters

(2020) Fangyuan Zhou et al.   CHEMISTRY-A EUROPEAN JOURNAL

Access to Divergent Fluorinated Enynes and Arenes via Palladium-Catalyzed Ring-Opening Alkynylation of gem-Difluorinated Cyclopropanes

(2020) Ebrahim-Alkhalil M. A. Ahmed et al.   ORGANIC LETTERS

Synthesis of Monofluoroalkenes through Visible-Light-Promoted Defluorinative Alkylation of gem-Difluoroalkenes with 4-Alkyl-1,4-dihydropyridines

(2020) Hai-Wu Du et al.   ORGANIC LETTERS

Recent Advances in Transition Metal‐Catalyzed Functionalization of gem ‐Difluoroalkenes

(2020) Suvajit Koley et al.   ISRAEL JOURNAL OF CHEMISTRY

Recent Advances of Cinnamic Acids in Organic Synthesis

(2020) Lihua Chen et al.   Asian Journal of Organic Chemistry

Organocatalytic Nucleophilic Substitution Reaction of gem-Difluoroalkenes with Ketene Silyl Acetals

(2019) Azusa Kondoh et al.   ORGANIC LETTERS

Mn(II)-Catalyzed C–H Alkylation of Imidazopyridines and N-Heteroarenes via Decarbonylative and Cross-Dehydrogenative Coupling

(2019) Sadhanendu Samanta et al.   JOURNAL OF ORGANIC CHEMISTRY

Nucleophilic Substitution of gem-Difluoroalkenes with TMSNu Promoted by Catalytic Amounts of Cs2CO3

(2019) Ling-Feng Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Regio- and Stereoselective Alkenylation of Allenoates with gem-Difluoroalkenes: Facile Access to Fluorinated 1,4-Enynes Bearing an All-Carbon Quaternary Center

(2019) Qi-Qi Zhang et al.   ORGANIC LETTERS

Palladium-Catalyzed Stereoselective Defluorination Arylation/Alkenylation/Alkylation of gem-Difluorinated Cyclopropanes

(2019) Ebrahim-Alkhalil M. A. Ahmed et al.   ORGANIC LETTERS

Metal‐free synthesis of 3,4‐dihydroquinolin‐2(1H)‑ones via cascade oxidative decarbonylative radical alkylation/cyclization of cinnamamides with aliphatic aldehydes

(2019) Xuemei Xu et al.   Asian Journal of Organic Chemistry

Nickel-Catalyzed Defluorinative Reductive Cross-Coupling Reaction of gem-Difluoroalkenes with Thiosulfonate or Selenium Sulfonate

(2019) Jian Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Nickel-Catalyzed Enantioselective Reductive Aryl Fluoroalkenylation of Alkenes

(2019) Teng Ma et al.   ACS Catalysis

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

(2018) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Alkylated Monofluoroalkenes via Fe-Catalyzed Defluorinative Cross-Coupling of Donor Alkenes with gem-Difluoroalkenes

(2018) Ling Yang et al.   ORGANIC LETTERS

Zinc-Mediated Decarboxylative Alkylation of Gem-difluoroalkenes

(2018) Liting Yu et al.   ORGANIC LETTERS

Synthesis of Monofluoroalkenes: A Leap Forward

(2018) Jean-François Paquin et al.   SYNTHESIS-STUTTGART

Ruthenium(ii)-catalyzed α-fluoroalkenylation of arenes via C–H bond activation and C–F bond cleavage

(2018) Na Li et al.   Organic Chemistry Frontiers

Aliphatic Aldehyde: A Novel Radical Alkylating Reagent

(2018) Wen-Chao Yang et al.   ADVANCED SYNTHESIS & CATALYSIS

Nickel-Catalyzed Defluorinative Reductive Cross-Coupling of gem-Difluoroalkenes with Unactivated Secondary and Tertiary Alkyl Halides

(2017) Xi Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Experimental and Theoretical Studies on Rhodium-Catalyzed Coupling of Benzamides with 2,2-Difluorovinyl Tosylate: Diverse Synthesis of Fluorinated Heterocycles

(2017) Jia-Qiang Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–F/C–H Functionalization by Manganese(I) Catalysis: Expedient (Per)Fluoro-Allylations and Alkenylations

(2017) Daniel Zell et al.   ACS Catalysis

China's flourishing synthetic organofluorine chemistry: innovations in the new millennium

(2017) Qinghe Liu et al.   National Science Review

Palladium-Catalyzed Defluorinative Coupling of 1-Aryl-2,2-Difluoroalkenes and Boronic Acids: Stereoselective Synthesis of Monofluorostilbenes

(2016) Richard T. Thornbury et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aerobic Radical-Cascade Alkylation/Cyclization of α,β-Unsaturated Amides: an Efficient Approach to Quaternary Oxindoles

(2016) Promita Biswas et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Monofluoroalkenylation of Dimethylamino Compounds through Radical-Radical Cross-Coupling

(2016) Jin Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct synthesis of Z-alkenyl halides through catalytic cross-metathesis

(2016) Ming Joo Koh et al.   NATURE

Sterically Controlled Cu-Catalyzed or Transition-Metal-Free Cross-Coupling of gem-Difluoroalkenes with Tertiary, Secondary, and Primary Alkyl Grignard Reagents

(2016) Wenpeng Dai et al.   ORGANIC LETTERS

Cobalt(III)-Catalyzed Regio- and Stereoselective α-Fluoroalkenylation of Arenes with gem-Difluorostyrenes

(2016) Lingheng Kong et al.   ORGANIC LETTERS

Kinetically controlledE-selective catalytic olefin metathesis

(2016) Thach T. Nguyen et al.   SCIENCE

Metal-Free Oxidative Decarbonylative Coupling of Aliphatic Aldehydes with Azaarenes: Successful Minisci-Type Alkylation of Various Heterocycles

(2015) Ren-Jin Tang et al.   ADVANCED SYNTHESIS & CATALYSIS

Pd-Catalyzed Regioselective Activation ofgem-Difluorinated Cyclopropanes: A Highly Efficient Approach to 2-Fluorinated Allylic Scaffolds

(2015) Jun Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reactions of Carbonyl Compounds with Phosphorus Ylide Generated from Tribromofluoromethane and Tris(dimethylamino)phosphine

(2015) Go Hirai et al.   CHEMISTRY LETTERS

Dioxygen-Mediated Decarbonylative CH Alkylation of Heteroaromatic Bases with Aldehydes

(2015) Subhasis Paul et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nickel-catalyzed Suzuki–Miyaura type cross-coupling reactions of (2,2-difluorovinyl)benzene derivatives with arylboronic acids

(2015) Yang Xiong et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enzymatic Fluorination and Biotechnological Developments of the Fluorinase

(2014) David O’Hagan et al.   CHEMICAL REVIEWS

Palladium- and Copper-Catalyzed Stereocontrolled Direct CH Fluoroalkenylation of Heteroarenes usinggem-Bromofluoroalkenes

(2013) Cédric Schneider et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Domino Synthesis of Fluorine-Substituted Polycyclic Aromatic Hydrocarbons: 1,1-Difluoroallenes as Synthetic Platforms

(2013) Kohei Fuchibe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Synthetic approaches to monofluoroalkenes

(2011) Grégory Landelle et al.   CHEMICAL SOCIETY REVIEWS

Preparation of (Z)-1-fluoro-1-alkenyl carboxylates, carbonates and carbamates through chromium mediated transformation of dibromofluoromethylcarbinyl esters and the reactivity as double acyl group donors

(2011) Akio Saito et al.   JOURNAL OF FLUORINE CHEMISTRY

Synthesis of Fluoroolefins via Julia-Kocienski Olefination

(2010) Barbara Zajc et al.   SYNTHESIS-STUTTGART

Fluoroalkene modification of mercaptoacetamide-based histone deacetylase inhibitors

(2009) Satoshi Osada et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Asymmetric Epoxidation of Fluoroolefins by Chiral Dioxirane. Fluorine Effect on Enantioselectivity

(2009) O. Andrea Wong et al.   JOURNAL OF ORGANIC CHEMISTRY

Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of α-helical anti-HIV peptide analogues

(2009) Shinya Oishi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Fluoroolefins as amide bond mimics in dipeptidyl peptidase IV inhibitors

(2008) Scott D. Edmondson et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Chemo-enzymatic fluorination of unactivated organic compounds

(2008) Andrea Rentmeister et al.   Nature Chemical Biology

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS