Pd-Catalyzed Regioselective Activation ofgem-Difluorinated Cyclopropanes: A Highly Efficient Approach to 2-Fluorinated Allylic Scaffolds

Difluorohomologation of Ketones

(2015) Mikhail D. Kosobokov et al.   ORGANIC LETTERS

Friedel-Crafts Reaction of Benzyl Fluorides: Selective Activation of CF Bonds as Enabled by Hydrogen Bonding

(2014) Pier Alexandre Champagne et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective CF Bond Activation of Hexafluoropropylene on Palladium(0): Formation of a Cationic η2-Perfluoroallylpalladium Complex

(2014) Masato Ohashi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Double CF Bond Activation through β-Fluorine Elimination: Nickel-Mediated [3+2] Cycloaddition of 2-Trifluoromethyl-1-alkenes with Alkynes

(2014) Tomohiro Ichitsuka et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Intramolecular CH Difluoroalkylation: Synthesis of Substituted 3,3-Difluoro-2-oxindoles

(2014) Shi-Liang Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed endo-type trifluoromethylarylation of alkynes

(2014) Jun Xu et al.   CHEMICAL COMMUNICATIONS

Pd-Catalyzed Nucleophilic Fluorination of Aryl Bromides

(2014) Hong Geun Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Unusual Reaction Behavior of gem-Difluorocyclopropane Derivatives: Stereoselective Synthesis of β-Monofluoroallylic Alcohols, Ethers, Esters, and Amide

(2014) Takashi Nihei et al.   ORGANIC LETTERS

Synthesis of gem-Difluoromethylene Building Blocks through Regioselective Allylation of gem-Difluorocyclopropanes

(2014) Daisuke Munemori et al.   ORGANIC LETTERS

Domino Synthesis of Fluorine-Substituted Polycyclic Aromatic Hydrocarbons: 1,1-Difluoroallenes as Synthetic Platforms

(2013) Kohei Fuchibe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Hydrodefluorination of Fluoroarenes by Copper Hydride Intermediates

(2013) Hongbin Lv et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis ofgem-Difluorocyclopropa(e)nes and O-, S-, N-, and P-Difluoromethylated Compounds with TMSCF2Br

(2013) Lingchun Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-CatalyzedOrtho-Selective CF Activation of Polyfluoroarenes with Triethylsilane: A Facile Access to Partially Fluorinated Aromatics

(2013) Zhao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Fluorinated Building Blocks by Transition-Metal-Mediated Hydrodefluorination Reactions

(2013) Moritz F. Kuehnel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Difluoromethyl Ethers with Difluoromethyltriflate

(2013) Patrick S. Fier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conversion between Difluorocarbene and Difluoromethylene Ylide

(2013) Jian Zheng et al.   CHEMISTRY-A EUROPEAN JOURNAL

C(sp3)–F Bond Activation of CF3-Substituted Anilines with Catalytically Generated Silicon Cations: Spectroscopic Evidence for a Hydride-Bridged Ru–S Dimer in the Catalytic Cycle

(2013) Timo Stahl et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt Fluorocarbenes: Cycloaddition Reactions with Tetrafluoroethylene and Reactivity of the Perfluorometallacyclic Products

(2013) Daniel J. Harrison et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enabling Nucleophilic Substitution Reactions of Activated Alkyl Fluorides through Hydrogen Bonding

(2013) Pier Alexandre Champagne et al.   ORGANIC LETTERS

Methyl 2,2-Difluoro-2-(fluorosulfonyl)acetate, a Difluorocarbene Reagent with Reactivity Comparable to That of Trimethylsilyl 2,2-Difluoro-2-(fluorosulfonyl)acetate (TFDA)

(2012) Steffen Eusterwiemann et al.   JOURNAL OF ORGANIC CHEMISTRY

C−F and C−H Bond Activation of Fluorobenzenes and Fluoropyridines at Transition Metal Centers: How Fluorine Tips the Scales

(2011) Eric Clot et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Use of Fluoride as a Leaving Group: SN2′ Displacement of a CF Bond on 3,3-Difluoropropenes with Organolithium Reagents To Give Direct Access to Monofluoroalkenes

(2011) Maxime Bergeron et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of gem-Difluorinated Cyclopropanes and Cyclopropenes: Trifluoromethyltrimethylsilane as a Difluorocarbene Source

(2011) Fei Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic approaches to monofluoroalkenes

(2011) Grégory Landelle et al.   CHEMICAL SOCIETY REVIEWS

Structure–Activity Relationships of C-17-Substituted Estratriene-3-O-sulfamates as Anticancer Agents

(2011) Fabrice Jourdan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Palladium-Catalyzed Coupling Reactions of Tetrafluoroethylene with Arylzinc Compounds

(2011) Masato Ohashi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Suzuki–Miyaura Reaction of Aryl Fluorides

(2011) Mamoru Tobisu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Titanium-Catalyzed C-F Activation of Fluoroalkenes

(2010) Moritz F. Kühnel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes

(2010) Fei Wang et al.   CHEMICAL COMMUNICATIONS

The Bridged Binding Mode as a New, Versatile Template for the Selective Activation of Carbon−Fluorine Bonds in Fluoroolefins: Activation of Trifluoroethylene

(2010) Michael E. Slaney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Substitution of Allylic Fluorides

(2009) Amaruka Hazari et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activation of Allylic CF bonds: Palladium-Catalyzed Allylic Amination of 3,3-Difluoropropenes

(2009) Xavier Pigeon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluoroalkene modification of mercaptoacetamide-based histone deacetylase inhibitors

(2009) Satoshi Osada et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of R-142086 as a Factor Xa (FXa) Inhibitor: Syntheses and Structure–Activity Relationships of Cinnamyl Derivatives

(2009) Tetsuji Noguchi et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

C−F Bond Activation in Organic Synthesis

(2009) Hideki Amii et al.   CHEMICAL REVIEWS

Asymmetric Epoxidation of Fluoroolefins by Chiral Dioxirane. Fluorine Effect on Enantioselectivity

(2009) O. Andrea Wong et al.   JOURNAL OF ORGANIC CHEMISTRY

Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of α-helical anti-HIV peptide analogues

(2009) Shinya Oishi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres

(2009) Tetsuo Narumi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

S-Ribosylhomocysteine analogues with the carbon-5 and sulfur atoms replaced by a vinyl or (fluoro)vinyl unit

(2008) Stanislaw F. Wnuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of Poly(arylenevinylene)s with Fluorinated Vinylene Units

(2008) Francesco Babudri et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Biological Activity of Fluorinated Combretastatin Analogues

(2008) Domenico Alloatti et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ring-Opening Reactions of Difluoro(methylene)cyclopropanes with Halogens and Amines

(2008) Xiao-Chun Hang et al.   JOURNAL OF ORGANIC CHEMISTRY