Single cell functional genomics reveals plasticity of subcutaneous white adipose tissue (WAT) during early postnatal development

A suite of new Dre recombinase drivers markedly expands the ability to perform intersectional genetic targeting

(2021) Ximeng Han et al.   Cell Stem Cell

Asc-1 regulates white versus beige adipocyte fate in a subcutaneous stromal cell population

(2021) Lisa Suwandhi et al.   Nature Communications

Single cell approaches to address adipose tissue stromal cell heterogeneity

(2020) Elizabeth A. Rondini et al.   BIOCHEMICAL JOURNAL

ESRRG and PERM1 Govern Mitochondrial Conversion in Brite/Beige Adipocyte Formation

(2020) Sebastian Müller et al.   Frontiers in Endocrinology

Toward a Consensus View of Mammalian Adipocyte Stem and Progenitor Cell Heterogeneity

(2020) Radiana Ferrero et al.   TRENDS IN CELL BIOLOGY

Plasticity of Epididymal Adipose Tissue in Response to Diet-Induced Obesity at Single-Nucleus Resolution

(2020) Anitta Kinga Sárvári et al.   Cell Metabolism

SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data

(2020) Matthew D Young et al.   GigaScience

Testosterone metabolites differentially regulate obesogenesis and fat distribution

(2020) Zachary L. Sebo et al.   Molecular Metabolism

Integrative single-cell analysis

(2019) Tim Stuart et al.   NATURE REVIEWS GENETICS

Adventitial Stromal Cells Define Group 2 Innate Lymphoid Cell Tissue Niches

(2019) Madelene W. Dahlgren et al.   IMMUNITY

Expression and activity of the cortisol-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 is tissue and species-specific

(2019) Christine Dammann et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Identification of a mesenchymal progenitor cell hierarchy in adipose tissue

(2019) David Merrick et al.   SCIENCE

DoubletFinder: Doublet Detection in Single-Cell RNA Sequencing Data Using Artificial Nearest Neighbors

(2019) Christopher S. McGinnis et al.   Cell Systems

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Genomic imprinting and its effects on postnatal growth and adult metabolism

(2019) Steven J. Millership et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Stromal cells maintain immune cell homeostasis in adipose tissue via production of interleukin-33

(2019) T. Mahlakõiv et al.   Science Immunology

Maturation of White Adipose Tissue Function in C57BL/6j Mice From Weaning to Young Adulthood

(2019) Andrea Kodde et al.   Frontiers in Physiology

Fast, sensitive and accurate integration of single-cell data with Harmony

(2019) Ilya Korsunsky et al.   NATURE METHODS

Single cell analysis reveals immune cell–adipocyte crosstalk regulating the transcription of thermogenic adipocytes

(2019) Prashant Rajbhandari et al.   eLife

Deconstructing Adipogenesis Induced by β3-Adrenergic Receptor Activation with Single-Cell Expression Profiling

(2018) Rayanne B. Burl et al.   Cell Metabolism

Plasma steroids, body composition, and fat distribution: effects of age, sex, and exercise training

(2018) Zihong He et al.   INTERNATIONAL JOURNAL OF OBESITY

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

(2018) Kerrin S. Small et al.   NATURE GENETICS

Distinct macrophage populations direct inflammatory versus physiological changes in adipose tissue

(2018) David A. Hill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Energy metabolism of white adipose tissue and insulin resistance in humans

(2018) Kálmán Bódis et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

A stromal cell population that inhibits adipogenesis in mammalian fat depots

(2018) Petra C. Schwalie et al.   NATURE

Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice

(2018) Chelsea Hepler et al.   eLife

iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data

(2018) Steven Xijin Ge et al.   BMC BIOINFORMATICS

Developmental and functional heterogeneity of white adipocytes within a single fat depot

(2018) Kevin Y Lee et al.   EMBO JOURNAL

Androgens modulate glucocorticoid receptor activity in adipose tissue and liver

(2018) Dieuwertje C E Spaanderman et al.   JOURNAL OF ENDOCRINOLOGY

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Bach1: Function, Regulation, and Involvement in Disease

(2018) Xinyue Zhang et al.   Oxidative Medicine and Cellular Longevity

chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data

(2017) Alicia N Schep et al.   NATURE METHODS

Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network

(2017) Annie Varrault et al.   NUCLEIC ACIDS RESEARCH

Puberty is an important developmental period for the establishment of adipose tissue mass and metabolic homeostasis

(2017) Brandon Holtrup et al.   Adipocyte

DKK3 (Dickkopf 3) Alters Atherosclerotic Plaque Phenotype Involving Vascular Progenitor and Fibroblast Differentiation Into Smooth Muscle Cells

(2017) Eirini Karamariti et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Metabolic heterogeneity of activated beige/brite adipocytes in inguinal adipose tissue

(2017) Yun-Hee Lee et al.   Scientific Reports

Transcriptional Regulation by Nrf2

(2017) Claudia Tonelli et al.   ANTIOXIDANTS & REDOX SIGNALING

The glucocorticoid receptor: cause of or cure for obesity?

(2016) Kezia John et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mest and Sfrp5 are biomarkers for healthy adipose tissue

(2016) Magdalena Jura et al.   BIOCHIMIE

The Bach Family of Transcription Factors: A Comprehensive Review

(2016) Yin Zhou et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Adipose tissue in control of metabolism

(2016) Liping Luo et al.   JOURNAL OF ENDOCRINOLOGY

Glucocorticoid Receptor Accelerates, but Is Dispensable for, Adipogenesis

(2016) Young-Kwon Park et al.   MOLECULAR AND CELLULAR BIOLOGY

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

The critical period for brown adipocyte development: Genetic and environmental influences

(2016) Agnieszka Chabowska-Kita et al.   Obesity

Adipose Tissue Remodeling: Its Role in Energy Metabolism and Metabolic Disorders

(2016) Sung Sik Choe et al.   Frontiers in Endocrinology

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

Low ambient temperature during early postnatal development fails to cause a permanent induction of brown adipocytes

(2015) Agnieszka Chabowska-Kita et al.   FASEB JOURNAL

PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity

(2015) Tomoaki Iwayama et al.   GENES & DEVELOPMENT

A systems-level approach to parental genomic imprinting: the imprinted gene network includes extracellular matrix genes and regulates cell cycle exit and differentiation

(2015) Hala Al Adhami et al.   GENOME RESEARCH

Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity

(2015) Elise Jeffery et al.   NATURE CELL BIOLOGY

ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap

(2015) Tauno Metsalu et al.   NUCLEIC ACIDS RESEARCH

Cthrc1 controls adipose tissue formation, body composition, and physical activity

(2015) J. Patrizia Stohn et al.   Obesity

The role and interaction of imprinted genes in human fetal growth

(2015) G. E. Moore et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Inducible brown adipocytes in subcutaneous inguinal white fat: the role of continuous sympathetic stimulation

(2014) G. Andres Contreras et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

State of the art paper Biochemistry of adipose tissue: an endocrine organ

(2013) Marisa Coelho et al.   Archives of Medical Science

Identification of an Adipogenic Niche for Adipose Tissue Remodeling and Restoration

(2013) Yun-Hee Lee et al.   Cell Metabolism

Bi-directional interconversion of brite and white adipocytes

(2013) Matthias Rosenwald et al.   NATURE CELL BIOLOGY

Characterization of the adipocyte cellular lineage in vivo

(2013) Ryan Berry et al.   NATURE CELL BIOLOGY

Tracking adipogenesis during white adipose tissue development, expansion and regeneration

(2013) Qiong A Wang et al.   NATURE MEDICINE

Emerging Role of Nrf2 in Adipocytes and Adipose Biology

(2013) Kevin S. Schneider et al.   Advances in Nutrition

Androgen Receptor Influences on Body Defense System via Modulation of Innate and Adaptive Immune Systems

(2012) Jiann-Jyh Lai et al.   AMERICAN JOURNAL OF PATHOLOGY

The mouseMageb18gene encodes a ubiquitously expressed type I MAGE protein and regulates cell proliferation and apoptosis in melanoma B16-F0 cells

(2012) Yuquan Lin et al.   BIOCHEMICAL JOURNAL

IL-1 receptor 2 (IL-1R2) and its role in immune regulation

(2012) Vanessa A. Peters et al.   BRAIN BEHAVIOR AND IMMUNITY

Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human

(2012) Jun Wu et al.   CELL

In Vivo Identification of Bipotential Adipocyte Progenitors Recruited by β3-Adrenoceptor Activation and High-Fat Feeding

(2012) Yun-Hee Lee et al.   Cell Metabolism

Membrane-Tethered Delta-Like 1 Homolog (DLK1) Restricts Adipose Tissue Size by Inhibiting Preadipocyte Proliferation

(2012) S. B. Mortensen et al.   DIABETES

Inherent Plasticity of Brown Adipogenesis in White Fat of Mice Allows for Recovery from Effects of Post-Natal Malnutrition

(2012) Leslie P. Kozak et al.   PLoS One

Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis

(2011) K. Birsoy et al.   DEVELOPMENT

The spatiotemporal development of adipose tissue

(2011) J. Han et al.   DEVELOPMENT

Extensive chromatin remodelling and establishment of transcription factor ‘hotspots’ during early adipogenesis

(2011) Rasmus Siersbaek et al.   EMBO JOURNAL

Mechanisms Limiting Body Growth in Mammals

(2011) Julian C. Lui et al.   ENDOCRINE REVIEWS

The effects of glucocorticoids on adipose tissue lipid metabolism

(2011) Ashley J. Peckett et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The Genetics of Brown Adipocyte Induction in White Fat Depots

(2011) Leslie P. Kozak   Frontiers in Endocrinology

Adipogenic and lipolytic effects of chronic glucocorticoid exposure

(2010) Jonathan E. Campbell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Coordinated postnatal down-regulation of multiple growth-promoting genes: evidence for a genetic program limiting organ growth

(2010) Julian C. Lui et al.   FASEB JOURNAL

GREAT improves functional interpretation of cis-regulatory regions

(2010) Cory Y McLean et al.   NATURE BIOTECHNOLOGY

Characterization of Structure and Cellular Components of Aspirated and Excised Adipose Tissue

(2010) Hitomi Eto et al.   PLASTIC AND RECONSTRUCTIVE SURGERY

The Early Nutritional Environment of Mice Determines the Capacity for Adipose Tissue Expansion by Modulating Genes of Caveolae Structure

(2010) Leslie P. Kozak et al.   PLoS One

Constitutively active Stat5A and Stat5B promote adipogenesis

(2010) Hiroshi Wakao et al.   Environmental Health and Preventive Medicine

Direct Effect of Glucocorticoids on Lipolysis in Adipocytes

(2009) Chong Xu et al.   MOLECULAR ENDOCRINOLOGY

An imprinted gene network that controls mammalian somatic growth is down-regulated during postnatal growth deceleration in multiple organs

(2008) Julian C. Lui et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Identification of White Adipocyte Progenitor Cells In Vivo

(2008) Matthew S. Rodeheffer et al.   CELL

Interferon Regulatory Factors Are Transcriptional Regulators of Adipogenesis

(2008) Jun Eguchi et al.   Cell Metabolism

An Extensive Genetic Program Occurring during Postnatal Growth in Multiple Tissues

(2008) Gabriela P. Finkielstain et al.   ENDOCRINOLOGY

Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance

(2008) Larissa Nikonova et al.   FASEB JOURNAL

The secretory function of adipocytes in the physiology of white adipose tissue

(2008) Ping Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dynamics of fat cell turnover in humans

(2008) Kirsty L. Spalding et al.   NATURE