Genomic imprinting and its effects on postnatal growth and adult metabolism

Genomic Imprinting and Physiological Processes in Mammals

(2019) Valter Tucci et al.   CELL

Neuronatin regulates pancreatic β cell insulin content and secretion

(2018) Steven J. Millership et al.   JOURNAL OF CLINICAL INVESTIGATION

Loss of Imprinting of Cdkn1c Protects against Age and Diet-Induced Obesity

(2018) Mathew Van de Pette et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice

(2018) Steven J. Millership et al.   Molecular Metabolism

Targeted demethylation at the CDKN1C/p57 locus induces human β cell replication

(2018) Kristy Ou et al.   JOURNAL OF CLINICAL INVESTIGATION

Visualizing Changes in Cdkn1c Expression Links Early-Life Adversity to Imprint Mis-regulation in Adults

(2017) Mathew Van de Pette et al.   Cell Reports

Trim28 Haploinsufficiency Triggers Bi-stable Epigenetic Obesity

(2016) Kevin Dalgaard et al.   CELL

Recent Advances in Imprinting Disorders

(2016) L. Soellner et al.   CLINICAL GENETICS

Fetus-derived DLK1 is required for maternal metabolic adaptations to pregnancy and is associated with fetal growth restriction

(2016) Mary A M Cleaton et al.   NATURE GENETICS

Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome

(2016) Matthew Van De Pette et al.   PLoS Genetics

Progressive postnatal decline in leptin sensitivity of arcuate hypothalamic neurons in theMagel2-null mouse model of Prader–Willi syndrome

(2015) Igor Pravdivyi et al.   HUMAN MOLECULAR GENETICS

Phenotypic Outcomes of Imprinted Gene Models in Mice: Elucidation of Pre- and Postnatal Functions of Imprinted Genes

(2014) Mary A.M. Cleaton et al.   Annual Review of Genomics and Human Genetics

Grb10 Promotes Lipolysis and Thermogenesis by Phosphorylation-Dependent Feedback Inhibition of mTORC1

(2014) Meilian Liu et al.   Cell Metabolism

Genomic imprinting in development, growth, behavior and stem cells

(2014) Robert N. Plasschaert et al.   DEVELOPMENT

Isolating the role of elevated Phlda2 in asymmetric late fetal growth restriction in mice

(2014) S. J. Tunster et al.   Disease Models & Mechanisms

Role of Gsα in Central Regulation of Energy and Glucose Metabolism

(2014) L. Weinstein   HORMONE AND METABOLIC RESEARCH

Targeting the cell cycle inhibitor p57Kip2 promotes adult human β cell replication

(2014) Dana Avrahami et al.   JOURNAL OF CLINICAL INVESTIGATION

The role of genomic imprinting in biology and disease: an expanding view

(2014) Jo Peters   NATURE REVIEWS GENETICS

DLK1/PREF1 regulates nutrient metabolism and protects from steatosis

(2014) Marika Charalambous et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Developmental Programming Mediated by Complementary Roles of Imprinted Grb10 in Mother and Pup

(2014) Michael Cowley et al.   PLOS BIOLOGY

Transgenerational Inheritance of Increased Fat Depot Size, Stem Cell Reprogramming, and Hepatic Steatosis Elicited by Prenatal Exposure to the Obesogen Tributyltin in Mice

(2013) Raquel Chamorro-García et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Imprinted genes in mouse placental development and the regulation of fetal energy stores

(2013) S J Tunster et al.   REPRODUCTION

Magel2 Is Required for Leptin-Mediated Depolarization of POMC Neurons in the Hypothalamic Arcuate Nucleus in Mice

(2013) Rebecca E. Mercer et al.   PLoS Genetics

Imprinted Gene Dosage Is Critical for the Transition to Independent Life

(2012) Marika Charalambous et al.   Cell Metabolism

DNA methylation at differentially methylated regions of imprinted genes is resistant to developmental programming by maternal nutrition

(2012) Elena Ivanova et al.   Epigenetics

Necdin Controls Proliferation of White Adipocyte Progenitor Cells

(2012) Kazushiro Fujiwara et al.   PLoS One

Mechanisms underlying the developmental origins of disease

(2012) Malgorzata S. Martin-Gronert et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

An Unbiased Assessment of the Role of Imprinted Genes in an Intergenerational Model of Developmental Programming

(2012) Elizabeth J. Radford et al.   PLoS Genetics

Fetal overgrowth in the Cdkn1c mouse model of Beckwith-Wiedemann syndrome

(2011) S. J. Tunster et al.   Disease Models & Mechanisms

Maternal High-Fat Diet Effects on Third-Generation Female Body Size via the Paternal Lineage

(2011) Gregory A. Dunn et al.   ENDOCRINOLOGY

The Thyroid Hormone-Inactivating Type III Deiodinase Is Expressed in Mouse and Human β-Cells and Its Targeted Inactivation Impairs Insulin Secretion

(2011) Mayrin C. Medina et al.   ENDOCRINOLOGY

Genomic imprinting as an adaptative model of developmental plasticity

(2011) Elizabeth J. Radford et al.   FEBS LETTERS

Distinct physiological and behavioural functions for parental alleles of imprinted Grb10

(2011) Alastair S. Garfield et al.   NATURE

Genomic imprinting: the emergence of an epigenetic paradigm

(2011) Anne C. Ferguson-Smith   NATURE REVIEWS GENETICS

Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets

(2011) I. Sandovici et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mammalian Genomic Imprinting

(2011) M. S. Bartolomei et al.   Cold Spring Harbor Perspectives in Biology

Global DNA methylation in the mouse liver is affected by methyl deficiency and arsenic in a sex-dependent manner

(2010) Keiko Nohara et al.   ARCHIVES OF TOXICOLOGY

Molecular mechanisms controlling human adipose tissue development: insights from monogenic lipodystrophies

(2010) Justin J. Rochford   EXPERT REVIEWS IN MOLECULAR MEDICINE

A single postnatal injection of oxytocin rescues the lethal feeding behaviour in mouse newborns deficient for the imprinted Magel2 gene

(2010) Fabienne Schaller et al.   HUMAN MOLECULAR GENETICS

Role of Early Hormonal and Nutritional Experiences in Shaping Feeding Behavior and Hypothalamic Development

(2010) Sebastien G. Bouret   JOURNAL OF NUTRITION

Specific transgenerational imprinting effects of the endocrine disruptor methoxychlor on male gametes

(2010) Christelle Stouder et al.   REPRODUCTION

Maternally-inherited Grb10 reduces placental size and efficiency

(2009) Marika Charalambous et al.   DEVELOPMENTAL BIOLOGY

Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression

(2009) David Monk et al.   HUMAN MOLECULAR GENETICS

A missense mutation in the non-neural G-protein α-subunit isoforms modulates susceptibility to obesity

(2009) M L Kelly et al.   INTERNATIONAL JOURNAL OF OBESITY

The role of GNAS and other imprinted genes in the development of obesity

(2009) L S Weinstein et al.   INTERNATIONAL JOURNAL OF OBESITY

The Imprinted Phlda2 Gene Regulates Extraembryonic Energy Stores

(2009) S. J. Tunster et al.   MOLECULAR AND CELLULAR BIOLOGY

Dual Ablation of Grb10 and Grb14 in Mice Reveals Their Combined Role in Regulation of Insulin Signaling and Glucose Homeostasis

(2009) Lowenna J. Holt et al.   MOLECULAR ENDOCRINOLOGY

Dynamic DNA methylation programs persistent adverse effects of early-life stress

(2009) Chris Murgatroyd et al.   NATURE NEUROSCIENCE

Transgenerational effects of the endocrine disruptor vinclozolin on the methylation pattern of imprinted genes in the mouse sperm

(2009) Christelle Stouder et al.   REPRODUCTION

Gene Dosage Effects of the Imprinted Delta-Like Homologue 1 (Dlk1/Pref1) in Development: Implications for the Evolution of Imprinting

(2009) Simao Teixeira da Rocha et al.   PLoS Genetics

Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet

(2008) Igor P. Pogribny et al.   BRAIN RESEARCH

Intergenerational Transmission of Glucose Intolerance and Obesity by In Utero Undernutrition in Mice

(2008) J. C. Jimenez-Chillaron et al.   DIABETES

Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance

(2008) Larissa Nikonova et al.   FASEB JOURNAL

Epigenetics, brain evolution and behaviour

(2008) Eric B. Keverne et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Histone Code Modifications Repress Glucose Transporter 4 Expression in the Intrauterine Growth-restricted Offspring

(2008) Nupur Raychaudhuri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Parasympathetic response in chick myocytes and mouse heart is controlled by SREBP

(2008) Ho-Jin Park et al.   JOURNAL OF CLINICAL INVESTIGATION

SnoRNA Snord116 (Pwcr1/MBII-85) Deletion Causes Growth Deficiency and Hyperphagia in Mice

(2008) Feng Ding et al.   PLoS One

Metabolic programming in the immediate postnatal period

(2008) Malathi Srinivasan et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM