Energy metabolism of white adipose tissue and insulin resistance in humans

Interorgan Metabolic Crosstalk in Human Insulin Resistance

(2018) Sofiya Gancheva et al.   PHYSIOLOGICAL REVIEWS

Role of adipocyte mitochondria in inflammation, lipemia and insulin sensitivity in humans: effects of pioglitazone treatment

(2017) X Xie et al.   INTERNATIONAL JOURNAL OF OBESITY

How to Measure Adipose Tissue Insulin Sensitivity

(2017) Esben Søndergaard et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Reduced ATGL-mediated lipolysis attenuates β-adrenergic-induced AMPK signaling, but not the induction of PKA-targeted genes, in adipocytes and adipose tissue

(2016) Rebecca E. K. MacPherson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Adipose-Specific Deficiency of Fumarate Hydratase in Mice Protects Against Obesity, Hepatic Steatosis, and Insulin Resistance

(2016) Hao Yang et al.   DIABETES

De Novo Lipogenesis Products and Endogenous Lipokines

(2016) Mustafa Yilmaz et al.   DIABETES

Adipose tissue in control of metabolism

(2016) Liping Luo et al.   JOURNAL OF ENDOCRINOLOGY

Proteomics analyses of subcutaneous adipocytes reveal novel abnormalities in human insulin resistance

(2016) Xitao Xie et al.   Obesity

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice

(2015) Gabriele Schoiswohl et al.   ENDOCRINOLOGY

Adipose tissue and metabolic syndrome: too much, too little or neither

(2015) Scott M. Grundy   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

De novo lipogenesis in metabolic homeostasis: More friend than foe?

(2015) Giovanni Solinas et al.   Molecular Metabolism

Adipose tissue mitochondrial dysfunction triggers a lipodystrophic syndrome with insulin resistance, hepatosteatosis, and cardiovascular complications

(2014) Cecile Vernochet et al.   FASEB JOURNAL

Secretion of fatty acid binding protein aP2 from adipocytes through a nonclassical pathway in response to adipocyte lipase activity

(2014) Meric Erikci Ertunc et al.   JOURNAL OF LIPID RESEARCH

Null Mutation in Hormone-Sensitive Lipase Gene and Risk of Type 2 Diabetes

(2014) Jessica S. Albert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Lipolysis in lipid turnover, cancer cachexia, and obesity-induced insulin resistance

(2014) Peter Arner et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Type 2 diabetes in South Asians: similarities and differences with white Caucasian and other populations

(2013) Unjali P. Gujral et al.   Annals of the New York Academy of Sciences

Adipocyte Lipid Chaperone aP2 Is a Secreted Adipokine Regulating Hepatic Glucose Production

(2013) Haiming Cao et al.   Cell Metabolism

Insulin signalling mechanisms for triacylglycerol storage

(2013) M. P. Czech et al.   DIABETOLOGIA

De novo lipogenesis in human fat and liver is linked to ChREBP-β and metabolic health

(2013) Leah Eissing et al.   Nature Communications

Partial Inhibition of Adipose Tissue Lipolysis Improves Glucose Metabolism and Insulin Sensitivity Without Alteration of Fat Mass

(2013) Amandine Girousse et al.   PLOS BIOLOGY

Regulation of glucose homoeostasis by brown adipose tissue

(2013) Vivian Peirce et al.   Lancet Diabetes & Endocrinology

Hidden Variant of ChREBP in Fat Links Lipogenesis to Insulin Sensitivity

(2012) Renaud Dentin et al.   Cell Metabolism

Inflammation and Lipid Signaling in the Etiology of Insulin Resistance

(2012) Christopher K. Glass et al.   Cell Metabolism

Decreased Transcription of ChREBP- /  Isoforms in Abdominal Subcutaneous Adipose Tissue of Obese Adolescents With Prediabetes or Early Type 2 Diabetes: Associations With Insulin Resistance and Hyperglycemia

(2012) R. Kursawe et al.   DIABETES

Abdominal Superficial Subcutaneous Fat: A putative distinct protective fat subdepot in type 2 diabetes

(2012) R. Golan et al.   DIABETES CARE

Mitochondrial dysfunction leads to impairment of insulin sensitivity and adiponectin secretion in adipocytes

(2012) Chih-Hao Wang et al.   FEBS Journal

Dietary obesity-associated Hif1  activation in adipocytes restricts fatty acid oxidation and energy expenditure via suppression of the Sirt2-NAD+ system

(2012) J. Krishnan et al.   GENES & DEVELOPMENT

Deep subcutaneous adipose tissue is more saturated than superficial subcutaneous adipose tissue

(2012) J Lundbom et al.   INTERNATIONAL JOURNAL OF OBESITY

Structural and inflammatory heterogeneity in subcutaneous adipose tissue: Relation with liver histopathology in morbid obesity

(2012) Joan Tordjman et al.   JOURNAL OF HEPATOLOGY

A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism

(2012) Mark A. Herman et al.   NATURE

Visceral fat and metabolic inflammation: the portal theory revisited

(2012) F. Item et al.   Obesity Reviews

The Action of D-Dopachrome Tautomerase as an Adipokine in Adipocyte Lipid Metabolism

(2012) Takeo Iwata et al.   PLoS One

Sex differences in human adipose tissues – the biology of pear shape

(2012) Kalypso Karastergiou et al.   Biology of Sex Differences

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

Mammalian Target of Rapamycin Complex 1 Suppresses Lipolysis, Stimulates Lipogenesis, and Promotes Fat Storage

(2010) P. Chakrabarti et al.   DIABETES

Cellularity and Adipogenic Profile of the Abdominal Subcutaneous Adipose Tissue From Obese Adolescents: Association With Insulin Resistance and Hepatic Steatosis

(2010) R. Kursawe et al.   DIABETES

The Role of Mitochondria in the Pathogenesis of Type 2 Diabetes

(2010) Mary-Elizabeth Patti et al.   ENDOCRINE REVIEWS

Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity

(2010) Regitze Kraunsøe et al.   JOURNAL OF PHYSIOLOGY-LONDON

Inverse relation between FASN expression in human adipose tissue and the insulin resistance level

(2010) María D Mayas et al.   Nutrition & Metabolism

Markers of de novo lipogenesis in adipose tissue: associations with small adipocytes and insulin sensitivity in humans

(2009) R. Roberts et al.   DIABETOLOGIA

AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency

(2009) Kathy Jaworski et al.   NATURE MEDICINE

The Gene Expression of the Main Lipogenic Enzymes is Downregulated in Visceral Adipose Tissue of Obese Subjects

(2009) Francisco J. Ortega et al.   Obesity

Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate

(2008) Gregory A. Locke et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Identification of a Lipokine, a Lipid Hormone Linking Adipose Tissue to Systemic Metabolism

(2008) Haiming Cao et al.   CELL

Identification and Functional Characterization of Adipose-specific Phospholipase A2(AdPLA)

(2008) Robin E. Duncan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Paradoxical Effect of Mitochondrial Respiratory Chain Impairment on Insulin Signaling and Glucose Transport in Adipose Cells

(2008) Xiarong Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

(2008) Catherine Postic et al.   JOURNAL OF CLINICAL INVESTIGATION