Natural Plant Compounds: Does Caffeine, Dipotassium Glycyrrhizinate, Curcumin, and Euphol Play Roles as Antitumoral Compounds in Glioblastoma Cell Lines?

Curcumin and Radiotherapy Exert Synergistic Anti-Glioma Effect In Vitro

(2021) Vasiliki Zoi et al.   Biomedicines

Modified ingenol semi-synthetic derivatives from Euphorbia tirucalli induce cytotoxicity on a large panel of human cancer cell lines

(2019) Viviane A. O Silva et al.   INVESTIGATIONAL NEW DRUGS

Growth Inhibitory Effects of Dipotassium Glycyrrhizinate in Glioblastoma Cell Lines by Targeting MicroRNAs Through the NF-κB Signaling Pathway

(2019) Gabriel Alves Bonafé et al.   Frontiers in Cellular Neuroscience

MicroRNA 145 enhances chemosensitivity of glioblastoma stem cells to demethoxycurcumin

(2019) Chunfa Qian et al.   Cancer Management and Research

MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway

(2018) Shi Yin et al.   CANCER BIOLOGY & THERAPY

Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells

(2018) Viviane A. O. Silva et al.   INVESTIGATIONAL NEW DRUGS

Evaluation of antioxidant and anti-inflammatory efficacy of caffeine in rat model of neurotoxicity

(2018) Eman N. Hosny et al.   NUTRITIONAL NEUROSCIENCE

Paraptosis in human glioblastoma cell line induced by curcumin

(2018) Monika Garrido-Armas et al.   TOXICOLOGY IN VITRO

A curcumin-loaded polymeric micelle as a carrier of a microRNA-21 antisense-oligonucleotide for enhanced anti-tumor effects in a glioblastoma animal model

(2018) Xiaonan Tan et al.   Biomaterials Science

Caffeine Sensitizes U87-MG Human Glioblastoma Cells to Temozolomide through Mitotic Catastrophe by Impeding G2 Arrest

(2018) Ning Li et al.   Biomed Research International

Ingenol-3-Angelate Suppresses Growth of Melanoma Cells and Skin Tumor Development by Downregulation of NF-κB-Cox2 Signaling

(2018) Dunwei Wang et al.   MEDICAL SCIENCE MONITOR

Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma

(2018) Bryan G. Harder et al.   Frontiers in Oncology

Treatment of novel IL17A inhibitor in glioblastoma implementing 3rd generation co-culture cell line and patient-derived tumor model

(2017) Md Shamsuddin Sultan Khan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Quantitative Analysis of Ingenol in Euphorbia species via Validated Isotope Dilution Ultra-high Performance Liquid Chromatography Tandem Mass Spectrometry

(2017) Tibor Béres et al.   PHYTOCHEMICAL ANALYSIS

PT93, a novel caffeic acid amide derivative, suppresses glioblastoma cells migration, proliferation and MMP-2/−9 expression

(2017) Kaishu Li et al.   Oncology Letters

MicroRNA-378 enhances inhibitory effect of curcumin on glioblastoma

(2017) Wende Li et al.   Oncotarget

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Euphorbia tirucalli modulates gene expression in larynx squamous cell carcinoma

(2016) Gabriela Bueno Franco-Salla et al.   BMC Complementary and Alternative Medicine

Caffeine suppresses the progression of human glioblastoma via cathepsin B and MAPK signaling pathway

(2016) Yu-Chen Cheng et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cancers of the brain and CNS: global patterns and trends in incidence

(2016) Adalberto Miranda-Filho et al.   NEURO-ONCOLOGY

Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

(2016) Rafael C. Dutra et al.   PHARMACOLOGICAL RESEARCH

The DNA damage/repair cascade in glioblastoma cell lines after chemotherapeutic agent treatment

(2015) LAURA ANNOVAZZI et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

NF-κB induces miR-148a to sustain TGF-β/Smad signaling activation in glioblastoma

(2015) Hui Wang et al.   Molecular Cancer

Induction of microRNA-146a is involved in curcumin-mediated enhancement of temozolomide cytotoxicity against human glioblastoma

(2015) HAO WU et al.   Molecular Medicine Reports

The antinociceptive effects of the tetracyclic triterpene euphol in inflammatory and neuropathic pain models: The potential role of PKCε

(2015) R.C. Dutra et al.   NEUROSCIENCE

Caffeine-induced nuclear translocation of FoxO1 triggers Bim-mediated apoptosis in human glioblastoma cells

(2015) Fei Sun et al.   TUMOR BIOLOGY

Glioblastoma: Molecular Pathways, Stem Cells and Therapeutic Targets

(2015) Meena Jhanwar-Uniyal et al.   Cancers

The Chemistry of Curcumin: From Extraction to Therapeutic Agent

(2014) Kavirayani Priyadarsini   MOLECULES

Is there new hope for therapeutic matrix metalloproteinase inhibition?

(2014) Roosmarijn E. Vandenbroucke et al.   NATURE REVIEWS DRUG DISCOVERY

Growth inhibitory in vitro effects of glycyrrhizic acid in U251 glioblastoma cell line

(2014) Song Li et al.   NEUROLOGICAL SCIENCES

Curcumin sensitizes glioblastoma to temozolomide by simultaneously generating ROS and disrupting AKT/mTOR signaling

(2014) HAITAO YIN et al.   ONCOLOGY REPORTS

Dual Role of Novel Ingenol Derivatives from Euphorbia tirucalli in HIV Replication: Inhibition of De Novo Infection and Activation of Viral LTR

(2014) Celina M. Abreu et al.   PLoS One

Human diseases caused by germline and somatic abnormalities in microRNA and microRNA-related genes

(2013) Yukio Kawahara   CONGENITAL ANOMALIES

Antioxidant and Antiinflammatory Activities of Curcumin on Diabetes Mellitus and its Complications

(2013) Bo Meng et al.   CURRENT PHARMACEUTICAL DESIGN

Turmeric curcumin inhibits entry of all hepatitis C virus genotypes into human liver cells

(2013) Anggakusuma et al.   GUT

Inhibition of NF- B Signaling Ablates the Invasive Phenotype of Glioblastoma

(2013) M.-A. Westhoff et al.   MOLECULAR CANCER RESEARCH

Missing the target: matrix metalloproteinase antitargets in inflammation and cancer

(2013) Antoine Dufour et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets

(2013) Elin Hadler-Olsen et al.   TUMOR BIOLOGY

Diterpenes from European Euphorbia Species Serving as Prototypes for Natural-Product-Based Drug Discovery

(2012) Andrea Vasas et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Alteration in the progression of dopamine neuron degeneration: May caffeine offer new perspective?

(2012) Micaela Morelli et al.   EXPERIMENTAL NEUROLOGY

Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis

(2012) Ming-Wei Lin et al.   FOOD AND CHEMICAL TOXICOLOGY

Associations between microRNA expression and mesenchymal marker gene expression in glioblastoma

(2012) Xinlong Ma et al.   NEURO-ONCOLOGY

Ingenol Mebutate Gel for Actinic Keratosis

(2012) Mark Lebwohl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Central roles of apoptotic proteins in mitochondrial function

(2012) S M Kilbride et al.   ONCOGENE

Euphol prevents experimental autoimmune encephalomyelitis in mice: Evidence for the underlying mechanisms

(2011) Rafael Cypriano Dutra et al.   BIOCHEMICAL PHARMACOLOGY

Autophagy as a therapeutic target in cancer

(2011) Ning Chen et al.   CANCER BIOLOGY & THERAPY

Clever cancer strategies with FoxO transcription factors

(2011) Kenneth Maiese et al.   CELL CYCLE

Curcumin

(2011) Mark G. Alexandrow et al.   EUROPEAN JOURNAL OF CANCER PREVENTION

SMN deficiency attenuates migration of U87MG astroglioma cells through the activation of RhoA

(2011) Víctor Caraballo-Miralles et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells

(2011) Bo Mi Ku et al.   MOLECULES AND CELLS

NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells

(2011) S. Galardi et al.   NUCLEIC ACIDS RESEARCH

Coffee and tea intake and risk of brain tumors in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort study

(2010) Dominique S Michaud et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

NFκB inhibitors induce cell death in glioblastomas

(2010) Alfeu Zanotto-Filho et al.   BIOCHEMICAL PHARMACOLOGY

Caffeine-Mediated Inhibition of Calcium Release Channel Inositol 1,4,5-Trisphosphate Receptor Subtype 3 Blocks Glioblastoma Invasion and Extends Survival

(2010) S. S. Kang et al.   CANCER RESEARCH

The effect of curcumin (turmeric) onAlzheimer′s disease: An overview

(2009) Shrikant Mishra et al.   Annals of Indian Academy of Neurology

MicroRNAs and Cancer: Short RNAs Go a Long Way

(2009) Andrea Ventura et al.   CELL

Antitumor activity of natural compounds, curcumin and PKF118-310, as Wnt/β-catenin antagonists against human osteosarcoma cells

(2009) Pay-Chin Leow et al.   INVESTIGATIONAL NEW DRUGS

Curcumin inhibits the Sonic Hedgehog signaling pathway and triggers apoptosis in medulloblastoma cells

(2009) Maha H. Elamin et al.   MOLECULAR CARCINOGENESIS

Glycyrrhizin attenuates the development of carrageenan-induced lung injury in mice

(2008) M MENEGAZZI et al.   PHARMACOLOGICAL RESEARCH

Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins

(2008) J. E. Chipuk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA