Euphol, a tetracyclic triterpene, from Euphorbia tirucalli induces autophagy and sensitizes temozolomide cytotoxicity on glioblastoma cells

In�vitro screening of cytotoxic activity of euphol from Euphorbia�tirucalli on a large panel of human cancer‑derived cell lines

(2018) Viviane Silva et al.   Experimental and Therapeutic Medicine

Diffuse Infiltrating Oligodendroglioma and Astrocytoma

(2017) Martin J. van den Bent et al.   JOURNAL OF CLINICAL ONCOLOGY

European Association for Neuro-Oncology (EANO) guideline on the diagnosis and treatment of adult astrocytic and oligodendroglial gliomas

(2017) Michael Weller et al.   LANCET ONCOLOGY

Molecular characterization of short-term primary cultures and comparison with corresponding tumor tissue of Brazilian glioblastoma patients

(2017) Adriana Cruvinel-Carloni et al.   Translational Cancer Research

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Cancers of the brain and CNS: global patterns and trends in incidence

(2016) Adalberto Miranda-Filho et al.   NEURO-ONCOLOGY

Isolation, characterization and screening of the in vitro cytotoxic activity of a novel L-amino acid oxidase (LAAOcdt) from Crotalus durissus terrificus venom on human cancer cell lines

(2016) Tuila Leveghim Teixeira et al.   TOXICON

Cytotoxicity of allitinib, an irreversible anti-EGFR agent, in a large panel of human cancer-derived cell lines: KRAS mutation status as a predictive biomarker

(2016) Renato José Silva-Oliveira et al.   CELLULAR ONCOLOGY

Recent Advances in the Development of Antineoplastic Agents Derived from Natural Products

(2015) Matthew Trendowski   DRUGS

The antinociceptive effects of the tetracyclic triterpene euphol in inflammatory and neuropathic pain models: The potential role of PKCε

(2015) R.C. Dutra et al.   NEUROSCIENCE

Definition of Primary and Secondary Glioblastoma--Response

(2014) H. Ohgaki et al.   CLINICAL CANCER RESEARCH

In Vitro and In Vivo Analysis of RTK Inhibitor Efficacy and Identification of Its Novel Targets in Glioblastomas

(2014) Olga Martinho et al.   Translational Oncology

Euphol arrests breast cancer cells at the G1 phase through the modulation of cyclin D1, p21 and p27 expression

(2013) LIN WANG et al.   Molecular Medicine Reports

Genetic oxidative stress variants and glioma risk in a Chinese population: a hospital-based case–control study

(2012) Peng Zhao et al.   BMC CANCER

The role of PKC/ERK1/2 signaling in the anti-inflammatory effect of tetracyclic triterpene euphol on TPA-induced skin inflammation in mice

(2012) Giselle F. Passos et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Euphol from Euphorbia tirucalli selectively inhibits human gastric cancer cell growth through the induction of ERK1/2-mediated apoptosis

(2012) Ming-Wei Lin et al.   FOOD AND CHEMICAL TOXICOLOGY

Diagnostic and therapeutic avenues for glioblastoma: no longer a dead end?

(2012) Shota Tanaka et al.   Nature Reviews Clinical Oncology

Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets

(2012) Vera Miranda-Gonçalves et al.   NEURO-ONCOLOGY

Euphol, a tetracyclic triterpene produces antinociceptive effects in inflammatory and neuropathic pain: The involvement of cannabinoid system

(2012) Rafael Cypriano Dutra et al.   NEUROPHARMACOLOGY

Euphol prevents experimental autoimmune encephalomyelitis in mice: Evidence for the underlying mechanisms

(2011) Rafael Cypriano Dutra et al.   BIOCHEMICAL PHARMACOLOGY

Autophagy in Brain Tumors: A New Target for Therapeutic Intervention

(2011) Niroop Kaza et al.   BRAIN PATHOLOGY

Autophagy as a therapeutic target in cancer

(2011) Ning Chen et al.   CANCER BIOLOGY & THERAPY

Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation

(2011) Ninel Azoitei et al.   NEURO-ONCOLOGY

Autophagy Interplay with Apoptosis and Cell Cycle Regulation in the Growth Inhibiting Effect of Resveratrol in Glioma Cells

(2011) Eduardo C. Filippi-Chiela et al.   PLoS One

Protein kinase D as a potential new target for cancer therapy

(2010) Courtney R. LaValle et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Integrated Molecular Genetic Profiling of Pediatric High-Grade Gliomas Reveals Key Differences With the Adult Disease

(2010) Barbara S. Paugh et al.   JOURNAL OF CLINICAL ONCOLOGY

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells

(2010) Lucia Ricci-Vitiani et al.   NATURE

Glioblastoma stem-like cells give rise to tumour endothelium

(2010) Rong Wang et al.   NATURE

Activity of the multikinase inhibitor dasatinib against ovarian cancer cells

(2009) G E Konecny et al.   BRITISH JOURNAL OF CANCER

The induction of autophagy by γ-radiation contributes to the radioresistance of glioma stem cells

(2009) Stephanie L. Lomonaco et al.   INTERNATIONAL JOURNAL OF CANCER