Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma
Published 2018 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Developments in Blood-Brain Barrier Penetrance and Drug Repurposing for Improved Treatment of Glioblastoma
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-10-23
DOI
10.3389/fonc.2018.00462
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cancer statistics, 2018
- (2018) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Mechanisms of enhanced antiglioma efficacy of polysorbate 80-modified paclitaxel-loaded PLGA nanoparticles by focused ultrasound
- (2018) Yingjia Li et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- EGFRvIII–Stat5 Signaling Enhances Glioblastoma Cell Migration and Survival
- (2018) Alison Roos et al. MOLECULAR CANCER RESEARCH
- Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2
- (2018) Mark C. de Gooijer et al. NEOPLASIA
- Repositioning chlorpromazine for treating chemoresistant glioma through the inhibition of cytochrome c oxidase bearing the COX4-1 regulatory subunit
- (2017) Claudia R. Oliva et al. Oncotarget
- Molecular and Microenvironmental Determinants of Glioma Stem-Like Cell Survival and Invasion
- (2017) Alison Roos et al. Frontiers in Oncology
- Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier
- (2016) David S. Hersh et al. CURRENT PHARMACEUTICAL DESIGN
- Repurposing antipsychotics as glioblastoma therapeutics: Potentials and challenges
- (2016) JIN-KU LEE et al. Oncology Letters
- High Intensity Focused Ultrasound Technology, its Scope and Applications in Therapy and Drug Delivery
- (2016) Christopher Peter Phenix et al. JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
- Metabolic/Proteomic Signature Defines Two Glioblastoma Subtypes With Different Clinical Outcome
- (2016) G. Marziali et al. Scientific Reports
- The synergistic effect of combination temozolomide and chloroquine treatment is dependent on autophagy formation and p53 status in glioma cells
- (2015) Seung Woo Lee et al. CANCER LETTERS
- Overcoming the blood–brain tumor barrier for effective glioblastoma treatment
- (2015) O. van Tellingen et al. DRUG RESISTANCE UPDATES
- Propentofylline inhibits glioblastoma cell invasion and survival by targeting the TROY signaling pathway
- (2015) Harshil D. Dhruv et al. JOURNAL OF NEURO-ONCOLOGY
- Biomarkers of Traumatic Injury Are Transported from Brain to Blood via the Glymphatic System
- (2015) B. A. Plog et al. JOURNAL OF NEUROSCIENCE
- Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio
- (2015) Tianzhi Yang et al. PHARMACEUTICAL RESEARCH
- Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo
- (2015) Zhiyun Yu et al. Oncotarget
- A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme
- (2014) Myrna R Rosenfeld et al. Autophagy
- Acetate Is a Bioenergetic Substrate for Human Glioblastoma and Brain Metastases
- (2014) Tomoyuki Mashimo et al. CELL
- Nanoscale drug delivery systems and the blood–brain barrier
- (2014) Igor Khalin et al. International Journal of Nanomedicine
- Chloroquine potentiates temozolomide cytotoxicity by inhibiting mitochondrial autophagy in glioma cells
- (2014) Yusuke S. Hori et al. JOURNAL OF NEURO-ONCOLOGY
- A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma
- (2014) Mark R. Gilbert et al. NEW ENGLAND JOURNAL OF MEDICINE
- Bevacizumab plus Radiotherapy–Temozolomide for Newly Diagnosed Glioblastoma
- (2014) Olivier L. Chinot et al. NEW ENGLAND JOURNAL OF MEDICINE
- Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
- (2014) A. P. Patel et al. SCIENCE
- Blood-Brain Barrier Permeable Gold Nanoparticles: An Efficient Delivery Platform for Enhanced Malignant Glioma Therapy and Imaging
- (2014) Yu Cheng et al. Small
- Emerging Therapies for Glioblastoma
- (2014) Alissa A. Thomas et al. JAMA Neurology
- The antipsychotic agent chlorpromazine induces autophagic cell death by inhibiting the Akt/mTOR pathway in human U-87MG glioma cells
- (2013) Soon Young Shin et al. CARCINOGENESIS
- Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage
- (2013) A. Paranjpe et al. CARCINOGENESIS
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- Phase I Study of GRN1005 in Recurrent Malignant Glioma
- (2013) J. Drappatz et al. CLINICAL CANCER RESEARCH
- Improving the prediction of drug disposition in the brain
- (2013) Kiril Lanevskij et al. Expert Opinion on Drug Metabolism & Toxicology
- Loss of Tsc1 accelerates malignant gliomagenesis when combined with oncogenic signals
- (2013) Daisuke Yamada et al. JOURNAL OF BIOCHEMISTRY
- Brain-wide pathway for waste clearance captured by contrast-enhanced MRI
- (2013) Jeffrey J. Iliff et al. JOURNAL OF CLINICAL INVESTIGATION
- TROY (TNFRSF19) Promotes Glioblastoma Survival Signaling and Therapeutic Resistance
- (2013) Joseph C. Loftus et al. MOLECULAR CANCER RESEARCH
- Diffusion of Macromolecules in the Brain: Implications for Drug Delivery
- (2013) Daniel J. Wolak et al. MOLECULAR PHARMACEUTICS
- Development, maintenance and disruption of the blood-brain barrier
- (2013) Birgit Obermeier et al. NATURE MEDICINE
- Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
- (2013) A. Sottoriva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma
- (2013) B. E. Johnson et al. SCIENCE
- Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma
- (2012) Y.-L. Hu et al. CANCER RESEARCH
- Drug Transport across the Blood–Brain Barrier
- (2012) William M Pardridge JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Aldehyde dehydrogenase 1A1—a new mediator of resistance to temozolomide in glioblastoma
- (2012) Andrea Schäfer et al. NEURO-ONCOLOGY
- Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing
- (2012) Marco Gerlinger et al. NEW ENGLAND JOURNAL OF MEDICINE
- Propentofylline Targets TROY, a Novel Microglial Signaling Pathway
- (2012) Valerie L. Jacobs et al. PLoS One
- A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid
- (2012) J. J. Iliff et al. Science Translational Medicine
- The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors
- (2011) E. A. Nelson et al. BLOOD
- Propentofylline decreases tumor growth in a rodent model of glioblastoma multiforme by a direct mechanism on microglia
- (2011) V. L. Jacobs et al. NEURO-ONCOLOGY
- Focused ultrasound disruption of the blood-brain barrier: a new frontier for therapeutic delivery in molecular neurooncology
- (2011) Arnold B. Etame et al. Neurosurgical Focus
- Moving beyond Rules: The Development of a Central Nervous System Multiparameter Optimization (CNS MPO) Approach To Enable Alignment of Druglike Properties
- (2010) Travis T. Wager et al. ACS Chemical Neuroscience
- The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
- (2010) John M. Heddleston et al. CELL CYCLE
- Chlorpromazine activates p21Waf1/Cip1gene transcription via early growth response-1 (Egr-1) in C6 glioma cells
- (2010) Soon Young Shin et al. EXPERIMENTAL AND MOLECULAR MEDICINE
- Acquisition of Temozolomide Chemoresistance in Gliomas Leads to Remodeling of Mitochondrial Electron Transport Chain
- (2010) Claudia R. Oliva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TROY (TNFRSF19) Is Overexpressed in Advanced Glial Tumors and Promotes Glioblastoma Cell Invasion via Pyk2-Rac1 Signaling
- (2010) V. M. Paulino et al. MOLECULAR CANCER RESEARCH
- Aldehyde dehydrogenase 1 positive glioblastoma cells show brain tumor stem cell capacity
- (2010) M. Rasper et al. NEURO-ONCOLOGY
- MSH6 Mutations Arise in Glioblastomas during Temozolomide Therapy and Mediate Temozolomide Resistance
- (2009) S. Yip et al. CLINICAL CANCER RESEARCH
- Chloroquine and its analogs: A new promise of an old drug for effective and safe cancer therapies
- (2009) V. Raja Solomon et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Convection-enhanced delivery for the treatment of brain tumors
- (2009) Waldemar Debinski et al. Expert Review of Neurotherapeutics
- Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
- (2009) Roger Stupp et al. LANCET ONCOLOGY
- Hypoxia-Induced Autophagy Is Mediated through Hypoxia-Inducible Factor Induction of BNIP3 and BNIP3L via Their BH3 Domains
- (2009) G. Bellot et al. MOLECULAR AND CELLULAR BIOLOGY
- Diffusion in Brain Extracellular Space
- (2008) Eva Syková et al. PHYSIOLOGICAL REVIEWS
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started