VDAC Modulation of Cancer Metabolism: Advances and Therapeutic Challenges
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Title
VDAC Modulation of Cancer Metabolism: Advances and Therapeutic Challenges
Authors
Keywords
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Journal
Frontiers in Physiology
Volume 12, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2021-09-29
DOI
10.3389/fphys.2021.742839
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Note: Only part of the references are listed.- A Calcium Guard in the Outer Membrane: Is VDAC a Regulated Gatekeeper of Mitochondrial Calcium Uptake?
- (2021) Paulina Sander et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Beyond the Warburg Effect: Oxidative and Glycolytic Phenotypes Coexist within the Metabolic Heterogeneity of Glioblastoma
- (2021) Tomás Duraj et al. Cells
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- The Glycolytic Pathway as a Target for Novel Onco-Immunology Therapies in Pancreatic Cancer
- (2021) Claudia Curcio et al. MOLECULES
- Pyruvate carboxylase and cancer progression
- (2021) Violet A. Kiesel et al. Cancer & Metabolism
- B cell heterogeneity, plasticity, and functional diversity in cancer microenvironments
- (2021) Yuan Wei et al. ONCOGENE
- The Endless Sources of Hepatocellular Carcinoma Heterogeneity
- (2021) Marina Barcena-Varela et al. Cancers
- VDAC and its interacting partners in plant and animal systems: an overview
- (2020) Poonam Kanwar et al. CRITICAL REVIEWS IN BIOTECHNOLOGY
- Structure and mechanism of the mitochondrial Ca2+ uniporter holocomplex
- (2020) Minrui Fan et al. NATURE
- Metabolic reprogramming and cancer progression
- (2020) Brandon Faubert et al. SCIENCE
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- (2020) Tatiana K. Rostovtseva et al. Frontiers in Physiology
- An Update on Mitochondrial Reactive Oxygen Species Production
- (2020) Ryan J. Mailloux Antioxidants
- Role of Mitochondria-Cytoskeleton Interactions in the Regulation of Mitochondrial Structure and Function in Cancer Stem Cells
- (2020) Jungmin Kim et al. Cells
- Electrical control of the cell energy metabolism at the level of mitochondrial outer membrane
- (2020) Victor V. Lemeshko BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Metabolic Flexibility of Mitochondria Plays a Key Role in Balancing Glucose and Fatty Acid Metabolism in the Diabetic Heart
- (2020) Jessica Gambardella et al. DIABETES
- Expression of voltage-dependent anion channels in endometrial cancer and its potential prognostic significance
- (2020) Paweł Jóźwiak et al. TUMOR BIOLOGY
- Neuronal metabolic rewiring promotes resilience to neurodegeneration caused by mitochondrial dysfunction
- (2020) E. Motori et al. Science Advances
- Take Advantage of Glutamine Anaplerosis, the Kernel of the Metabolic Rewiring in Malignant Gliomas
- (2020) Filipa Martins et al. Biomolecules
- Evidences of a Direct Relationship between Cellular Fuel Supply and Ciliogenesis Regulated by Hypoxic VDAC1-ΔC
- (2020) Monique Meyenberg Cunha-de Padua et al. Cancers
- VDAC1 is regulated by BRD4 and contributes to JQ1 resistance in breast cancer
- (2019) Guochao Yang et al. Oncology Letters
- The Pleiotropic Effects of Glutamine Metabolism in Cancer
- (2019) Alex Bott et al. Cancers
- Mechanisms and Implications of Metabolic Heterogeneity in Cancer
- (2019) Jiyeon Kim et al. Cell Metabolism
- JNK activation and translocation to mitochondria mediates mitochondrial dysfunction and cell death induced by VDAC opening and sorafenib in hepatocarcinoma cells
- (2019) K.A. Heslop et al. BIOCHEMICAL PHARMACOLOGY
- Relationship between inorganic ion distribution, resting membrane potential, and the ΔG′ of ATP hydrolysis: a new paradigm
- (2019) Richard L. Veech et al. FASEB JOURNAL
- The Structural Basis for Low Conductance in the Membrane Protein VDAC upon β-NADH Binding and Voltage Gating
- (2019) Raphael Böhm et al. STRUCTURE
- Opening of voltage dependent anion channels promotes reactive oxygen species generation, mitochondrial dysfunction and cell death in cancer cells
- (2018) David N. DeHart et al. BIOCHEMICAL PHARMACOLOGY
- The multifaceted contributions of mitochondria to cellular metabolism
- (2018) Jessica B. Spinelli et al. NATURE CELL BIOLOGY
- VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis
- (2018) Andrea Magrì et al. Frontiers in Chemistry
- Mitochondrial Voltage-Dependent Anion Channel Protein Por1 Positively Regulates the Nuclear Localization of Saccharomyces cerevisiae AMP-Activated Protein Kinase
- (2018) Aishwarya Shevade et al. mSphere
- VDAC2 interacts with PFKP to regulate glucose metabolism and phenotypic reprogramming of glioma stem cells
- (2018) Kai Zhou et al. Cell Death & Disease
- Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
- (2018) Piyush B. Gupta et al. Cell Stem Cell
- VDAC2 enables BAX to mediate apoptosis and limit tumor development
- (2018) Hui San Chin et al. Nature Communications
- Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1
- (2017) Melissa M. Budelier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cancer stem cells revisited
- (2017) Eduard Batlle et al. NATURE MEDICINE
- Mitochondrial VDAC1: A Key Gatekeeper as Potential Therapeutic Target
- (2017) Amadou K. S. Camara et al. Frontiers in Physiology
- VDAC–Tubulin, an Anti-Warburg Pro-Oxidant Switch
- (2017) Eduardo N. Maldonado Frontiers in Oncology
- Erastin-Like Anti-Warburg Agents Prevent Mitochondrial Depolarization Induced by Free Tubulin and Decrease Lactate Formation in Cancer Cells
- (2017) David N. DeHart et al. SLAS Discovery
- The N-terminus of VDAC: Structure, mutational analysis, and a potential role in regulating barrel shape
- (2016) Sabbir R. Shuvo et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- The VDAC channel: Molecular basis for selectivity
- (2016) Marco Colombini BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Give it or take it: the flux of one-carbon in cancer cells
- (2016) Johannes Meiser et al. FEBS Journal
- News about VDAC1 in Hypoxia
- (2016) N. M. Mazure Frontiers in Oncology
- Alternative Fuels for Cancer Cells
- (2015) Melissa M. Keenan et al. CANCER JOURNAL
- New Perspectives on Proton Pumping in Cellular Respiration
- (2015) Mårten Wikström et al. CHEMICAL REVIEWS
- Restoration of mitochondria function as a target for cancer therapy
- (2015) Tariq A. Bhat et al. DRUG DISCOVERY TODAY
- Targeting mitochondria metabolism for cancer therapy
- (2015) Samuel E Weinberg et al. Nature Chemical Biology
- Defining normoxia, physoxia and hypoxia in tumours—implications for treatment response
- (2014) S R McKeown BRITISH JOURNAL OF RADIOLOGY
- Acetate Dependence of Tumors
- (2014) Sarah A. Comerford et al. CELL
- Who controls the ATP supply in cancer cells? Biochemistry lessons to understand cancer energy metabolism
- (2014) Rafael Moreno-Sánchez et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
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- Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
- (2013) Cosimo Commisso et al. NATURE
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- (2012) G L Robinson et al. ONCOGENE
- Reversible High Affinity Inhibition of Phosphofructokinase-1 by Acyl-CoA
- (2011) Christopher M. Jenkins et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Respiratory competent mitochondria in human ovarian and peritoneal cancer
- (2011) Hwee Ying Lim et al. MITOCHONDRION
- Reductive carboxylation supports growth in tumour cells with defective mitochondria
- (2011) Andrew R. Mullen et al. NATURE
- Impact of caloric and dietary restriction regimens on markers of health and longevity in humans and animals: a summary of available findings
- (2011) John F Trepanowski et al. Nutrition Journal
- Gene Expression Meta-Analysis Identifies VDAC1 as a Predictor of Poor Outcome in Early Stage Non-Small Cell Lung Cancer
- (2011) Claire Grills et al. PLoS One
- Phosphorylation of Voltage-Dependent Anion Channel by Serine/Threonine Kinases Governs Its Interaction with Tubulin
- (2011) Kely L. Sheldon et al. PLoS One
- Metabolic Positron Emission Tomography Imaging in Cancer Detection and Therapy Response
- (2011) Aizhi Zhu et al. SEMINARS IN ONCOLOGY
- Characterization of human VDAC isoforms: A peculiar function for VDAC3?
- (2010) Vito De Pinto et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- The pivotal roles of mitochondria in cancer: Warburg and beyond and encouraging prospects for effective therapies
- (2010) Saroj P. Mathupala et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Choosing between glycolysis and oxidative phosphorylation: A tumor's dilemma?
- (2010) Caroline Jose et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Free Tubulin Modulates Mitochondrial Membrane Potential in Cancer Cells
- (2010) E. N. Maldonado et al. CANCER RESEARCH
- The mitochondrial respiratory chain
- (2010) Peter R. Rich et al. Essays in Biochemistry
- Mitochondrial metabolite transport
- (2010) Ferdinando Palmieri et al. Essays in Biochemistry
- Oxidative phosphorylation is impaired by prolonged hypoxia in breast and possibly in cervix carcinoma
- (2010) Sara Rodríguez-Enríquez et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Mitochondrial bioenergetic adaptations of breast cancer cells to aglycemia and hypoxia
- (2010) Katarína Smolková et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- The 3D structures of VDAC represent a native conformation
- (2010) Sebastian Hiller et al. TRENDS IN BIOCHEMICAL SCIENCES
- Direct measurement of energy fluxes from mitochondria into cytoplasm in permeabilized cardiac cells in situ: some evidence for mitochondrial interactosome
- (2009) Natalia Timohhina et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- The Electrostatics of VDAC: Implications for Selectivity and Gating
- (2009) Om P. Choudhary et al. JOURNAL OF MOLECULAR BIOLOGY
- The published 3D structure of the VDAC channel: native or not?
- (2009) Marco Colombini TRENDS IN BIOCHEMICAL SCIENCES
- The ADP and ATP transport in mitochondria and its carrier
- (2008) Martin Klingenberg BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- Glycogen Synthase Kinase 3 Inhibition Slows Mitochondrial Adenine Nucleotide Transport and Regulates Voltage-Dependent Anion Channel Phosphorylation
- (2008) Samarjit Das et al. CIRCULATION RESEARCH
- Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration
- (2008) T. K. Rostovtseva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The crystal structure of mouse VDAC1 at 2.3 A resolution reveals mechanistic insights into metabolite gating
- (2008) R. Ujwal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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