Changes in systemic GDF15 across the adult lifespan and their impact on maximal muscle power: the Copenhagen Sarcopenia Study

Older adults with frailty syndrome present an altered platelet function and an increased level of circulating oxidative stress and mitochondrial dysfunction biomarker GDF-15

(2020) Diego Arauna et al.   FREE RADICAL BIOLOGY AND MEDICINE

Age- and Sex-Specific Changes in Lower-Limb Muscle Power Throughout the Lifespan

(2020) Julian Alcazar et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Plasma proteomic signature of the risk of developing mobility disability: A 9‐year follow‐up

(2020) Yusuke Osawa et al.   AGING CELL

GDF15 Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness

(2020) Maria Conte et al.   Frontiers in Immunology

Systematic review and analysis of human proteomics aging studies unveils a novel proteomic aging clock and identifies key processes that change with age

(2020) Adiv A. Johnson et al.   AGEING RESEARCH REVIEWS

Growth differentiation factor 15 protects against the aging‐mediated systemic inflammatory response in humans and mice

(2020) Ji Sun Moon et al.   AGING CELL

Antibody-mediated inhibition of GDF15–GFRAL activity reverses cancer cachexia in mice

(2020) Rowena Suriben et al.   NATURE MEDICINE

Relation between leg extension power and 30-s sit-to-stand muscle power in older adults: validation and translation to functional performance

(2020) Julian Alcazar et al.   Scientific Reports

Low relative mechanical power in older adults: An operational definition and algorithm for its application in the clinical setting

(2020) Jose Losa-Reyna et al.   EXPERIMENTAL GERONTOLOGY

Sit-to-stand muscle power test: Comparison between estimated and force plate-derived mechanical power and their association with physical function in older adults

(2020) Ivan Baltasar-Fernandez et al.   EXPERIMENTAL GERONTOLOGY

Elevated Plasma Growth and Differentiation Factor-15 is Associated with Slower Gait Speed and Lower Physical Performance in Healthy Community-Dwelling Adults

(2019) Richard D Semba et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Association of growth differentiation factor 15 with other key biomarkers, functional parameters and mortality in community-dwelling older adults

(2019) Dietrich Rothenbacher et al.   AGE AND AGEING

mTORC1 underlies age‐related muscle fiber damage and loss by inducing oxidative stress and catabolism

(2019) Huibin Tang et al.   AGING CELL

Growth differentiation factor 15: A novel biomarker with high clinical potential

(2019) Stéphanie Desmedt et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Growth differentiation factor 15 and geriatric conditions in acute coronary syndrome

(2019) Juan Sanchis et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

The Copenhagen Sarcopenia Study: lean mass, strength, power, and physical function in a Danish cohort aged 20–93 years

(2019) Charlotte Suetta et al.   Journal of Cachexia Sarcopenia and Muscle

Ethical guidelines for publishing in the Journal of Cachexia, Sarcopenia and Muscle : update 2019

(2019) Stephan Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Plasma proteomic signature of age in healthy humans

(2018) Toshiko Tanaka et al.   AGING CELL

Human Aging and Longevity Are Characterized by High Levels of Mitokines

(2018) Maria Conte et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Exercise increases circulating GDF15 in humans

(2018) Maximilian Kleinert et al.   Molecular Metabolism

Towards frailty biomarkers: Candidates from genes and pathways regulated in aging and age-related diseases

(2018) Ana Luisa Cardoso et al.   AGEING RESEARCH REVIEWS

The sit-to-stand muscle power test: An easy, inexpensive and portable procedure to assess muscle power in older people

(2018) Julian Alcazar et al.   EXPERIMENTAL GERONTOLOGY

GDF15 and Growth Control

(2018) Paul J. Emmerson et al.   Frontiers in Physiology

GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand

(2017) Linda Yang et al.   NATURE MEDICINE

The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL

(2017) Paul J Emmerson et al.   NATURE MEDICINE

Serum concentrations of insulin-like growth factor-1, members of the TGF-beta superfamily and follistatin do not reflect different stages of dynapenia and sarcopenia in elderly women

(2015) Marlene Hofmann et al.   EXPERIMENTAL GERONTOLOGY

Growth differentiation factor-15 is associated with muscle mass in chronic obstructive pulmonary disease and promotes muscle wastingin vivo

(2015) Mehul S. Patel et al.   Journal of Cachexia Sarcopenia and Muscle

Increased expression of GDF-15 may mediate ICU-acquired weakness by down-regulating muscle microRNAs

(2014) S. A. A. Bloch et al.   THORAX

Change in Growth Differentiation Factor 15 Concentrations over Time Independently Predicts Mortality in Community-Dwelling Elderly Individuals

(2013) K. M. Eggers et al.   CLINICAL CHEMISTRY

Sustained Elevation of Circulating Growth and Differentiation Factor-15 and a Dynamic Imbalance in Mediators of Muscle Homeostasis Are Associated With the Development of Acute Muscle Wasting Following Cardiac Surgery*

(2013) Susannah A.A. Bloch et al.   CRITICAL CARE MEDICINE

Concise Review: Growth Differentiation Factor 15 in Pathology: A Clinical Role?

(2013) Jill Corre et al.   Stem Cells Translational Medicine

Prognostic Utility of Novel Biomarkers of Cardiovascular Stress

(2012) Thomas J. Wang et al.   CIRCULATION

Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality

(2010) Fredrik E. Wiklund et al.   AGING CELL

Progressive Postnatal Motoneuron Loss in Mice Lacking GDF-15

(2009) J. Strelau et al.   JOURNAL OF NEUROSCIENCE