Concise Review: Growth Differentiation Factor 15 in Pathology: A Clinical Role?

Growth Differentiation Factor‐15 Deficiency Inhibits Atherosclerosis Progression by Regulating Interleukin‐6–Dependent Inflammatory Response to Vascular Injury

(2013) Gabriel A. Bonaterra et al.   Journal of the American Heart Association

Multiple myeloma-related deregulation of bone marrow-derived CD34+ hematopoietic stem and progenitor cells

(2012) I. Bruns et al.   BLOOD

Bioactivity and Prognostic Significance of Growth Differentiation Factor GDF15 Secreted by Bone Marrow Mesenchymal Stem Cells in Multiple Myeloma

(2012) J. Corre et al.   CANCER RESEARCH

Increased expression of the TGF-b superfamily cytokine MIC-1/GDF15 protects ApoE−/− mice from the development of atherosclerosis

(2012) Heiko Johnen et al.   CARDIOVASCULAR PATHOLOGY

Local substitution of GDF-15 improves axonal and sensory recovery after peripheral nerve injury

(2012) Leonore Mensching et al.   CELL AND TISSUE RESEARCH

Growth-Differentiation Factor 15 Predicts Worsening of Albuminuria in Patients With Type 2 Diabetes

(2012) M. E. Hellemons et al.   DIABETES CARE

Growth differentiation factor 15: An additional diagnostic tool for the risk stratification of developing heart failure in patients with operated congenital heart defects?

(2011) Kambiz Norozi et al.   AMERICAN HEART JOURNAL

Growth differentiation factor 15 in cardiovascular diseases: from bench to bedside

(2011) Xinye Xu et al.   BIOMARKERS

Macrophage inhibitory cytokine-1 transactivates ErbB family receptors via the activation of Src in SK-BR-3 human breast cancer cells

(2011) Yun-Jung Park et al.   BMB Reports

Growth-Differentiation Factor-15 Is a Robust, Independent Predictor of 11-Year Mortality Risk in Community-Dwelling Older Adults

(2011) Lori B. Daniels et al.   CIRCULATION

Elevated Plasma Growth Differentiation Factor-15 Correlates with Lymph Node Metastases and Poor Survival in Endometrial Cancer

(2011) A. C. Staff et al.   CLINICAL CANCER RESEARCH

Plasma Markers for Identifying Patients with Metastatic Melanoma

(2011) H. M. Kluger et al.   CLINICAL CANCER RESEARCH

The TGF-β superfamily cytokine, MIC-1/GDF15: A pleotrophic cytokine with roles in inflammation, cancer and metabolism

(2011) Samuel N. Breit et al.   GROWTH FACTORS

Positive regulation of osteoclastic differentiation by growth differentiation factor 15 upregulated in osteocytic cells under hypoxia

(2011) Eiichi Hinoi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis

(2011) Saskia C.A. de Jager et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The emerging role of hypoxia, HIF-1 and HIF-2 in multiple myeloma

(2011) S K Martin et al.   LEUKEMIA

Macrophage inhibitory cytokine-1 (MIC-1/GDF15) and mortality in end-stage renal disease

(2011) S. N. Breit et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Macrophage inhibitory cytokine-1 (MIC-1/GDF15): a new marker of all-cause mortality

(2010) Fredrik E. Wiklund et al.   AGING CELL

Macrophage Inhibitory Cytokine-1 Regulates Melanoma Vascular Development

(2010) Sung Jin Huh et al.   AMERICAN JOURNAL OF PATHOLOGY

GDF-15 Contributes to Proliferation and Immune Escape of Malignant Gliomas

(2010) P. Roth et al.   CLINICAL CANCER RESEARCH

Growth differentiation factor-15 as a prognostic biomarker in ovarian cancer

(2010) Anne Cathrine Staff et al.   GYNECOLOGIC ONCOLOGY

Growth/differentiation factor-15 is an abundant cytokine in human seminal plasma

(2010) K. Soucek et al.   HUMAN REPRODUCTION

Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancer

(2010) Murielle Mimeault et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Macrophage Inhibitory Cytokine 1: A New Prognostic Marker in Prostate Cancer

(2009) D. A. Brown et al.   CLINICAL CANCER RESEARCH

Growth differentiation factor-15 predicts mortality and morbidity after cardiac resynchronization therapy

(2009) P. W.X. Foley et al.   EUROPEAN HEART JOURNAL

Progressive Postnatal Motoneuron Loss in Mice Lacking GDF-15

(2009) J. Strelau et al.   JOURNAL OF NEUROSCIENCE

Overexpression of macrophage inhibitory cytokine-1 induces metastasis of human prostate cancer cells through the FAK–RhoA signaling pathway

(2009) S Senapati et al.   ONCOGENE

Expression of macrophage inhibitory cytokine-1 in prostate cancer bone metastases induces osteoclast activation and weight loss

(2009) Savita Wakchoure et al.   PROSTATE

Growth Differentiation Factor-15 in Idiopathic Pulmonary Arterial Hypertension

(2008) Nils Nickel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Growth Differentiation Factor-15 for Prognostic Assessment of Patients with Acute Pulmonary Embolism

(2008) Mareike Lankeit et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Elevated growth differentiation factor 15 expression in patients with congenital dyserythropoietic anemia type I

(2008) H. Tamary et al.   BLOOD

Growth differentiation factor 15 production is necessary for normal erythroid differentiation and is increased in refractory anaemia with ring-sideroblasts

(2008) Jean-Marie Ramirez et al.   BRITISH JOURNAL OF HAEMATOLOGY

Regulation of iron metabolism through GDF15 and hepcidin in pyruvate kinase deficiency

(2008) Armin Finkenstedt et al.   BRITISH JOURNAL OF HAEMATOLOGY

Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells

(2008) Kwang-Kyu Kim et al.   CARCINOGENESIS

Identification of Macrophage Inhibitory Cytokine-1 in Adipose Tissue and Its Secretion as an Adipokine by Human Adipocytes

(2008) Qi Ding et al.   ENDOCRINOLOGY

Macrophage Inhibitory Cytokine-1 Is Overexpressed in Malignant Melanoma and Is Associated with Tumorigenicity

(2008) Glen M. Boyle et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Expression of growth differentiation factor 15 is positively correlated with histopathological malignant grade and in vitro cell proliferation in oral squamous cell carcinoma

(2008) Lei Zhang et al.   ORAL ONCOLOGY