Association of peripheral blood DNA methylation level with Alzheimer’s disease progression

Identification of vascular dementia and Alzheimer's disease hub genes expressed in the frontal lobe and temporal cortex by weighted co-expression network analysis and construction of a protein–protein interaction

(2021) Xiaodou Tian et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex

(2021) Rebecca G. Smith et al.   Nature Communications

Comprehensive analysis of PM20D1 QTL in Alzheimer’s disease

(2020) Jose Vicente Sanchez-Mut et al.   Clinical Epigenetics

Combination Drug Therapy for the Management of Alzheimer’s Disease

(2020) Md. Tanvir Kabir et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA-107 Ameliorates Damage in a Cell Model of Alzheimer’s Disease by Mediating the FGF7/FGFR2/PI3K/Akt Pathway

(2020) Wei Chen et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Elevated Cerebrospinal Fluid and Plasma N-Cadherin in Alzheimer Disease

(2020) Ji-Young Choi et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Inexpensive, non-invasive biomarkers predict Alzheimer transition using machine learning analysis of the Alzheimer’s Disease Neuroimaging (ADNI) database

(2020) Juan Felipe Beltrán et al.   PLoS One

Alzheimer’s Patient Microglia Exhibit Enhanced Aging and Unique Transcriptional Activation

(2020) Karpagam Srinivasan et al.   Cell Reports

Harnessing peripheral DNA methylation differences in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease

(2020) Aparna Vasanthakumar et al.   Clinical Epigenetics

Inflammatory pathway analytes predicting rapid cognitive decline in MCI stage of Alzheimer’s disease

(2020) Jagan A. Pillai et al.   Annals of Clinical and Translational Neurology

Epigenome-wide association study of Alzheimer’s disease replicates 22 differentially methylated positions and 30 differentially methylated regions

(2020) Qingqin S. Li et al.   Clinical Epigenetics

Blood-derived DNA Methylation Signatures of Crohn’s Disease and Severity of Intestinal Inflammation

(2019) Hari K. Somineni et al.   GASTROENTEROLOGY

The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease

(2019) Luke W. Bonham et al.   Frontiers in Immunology

Amyloid PET, FDG-PET or MRI? - the power of different imaging biomarkers to detect progression of early Alzheimer’s disease

(2019) Marion Ortner et al.   BMC Neurology

The role of innate immune responses and neuroinflammation in amyloid accumulation and progression of Alzheimer's disease

(2019) Alessandra Webers et al.   IMMUNOLOGY AND CELL BIOLOGY

Alzheimer’s disease-associated (hydroxy)methylomic changes in the brain and blood

(2019) Roy Lardenoije et al.   Clinical Epigenetics

Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

(2018) Rebecca G. Smith et al.   Alzheimers & Dementia

PM20D1 is a quantitative trait locus associated with Alzheimer’s disease

(2018) Jose V. Sanchez-Mut et al.   NATURE MEDICINE

Peripheral DNA methylation, cognitive decline and brain aging: pilot findings from the Whitehall II imaging study

(2018) Leonidas Chouliaras et al.   Epigenomics

Biological function of Lemur tyrosine kinase 2 (LMTK2): implications in neurodegeneration

(2018) János Bencze et al.   Molecular Brain

Digit Symbol Substitution Test

(2018) Judith Jaeger   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex

(2018) Gilles Gasparoni et al.   Epigenetics & Chromatin

Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative

(2018) Dallas P. Veitch et al.   Alzheimers & Dementia

methylGSA: a Bioconductor package and Shiny app for DNA methylation data length bias adjustment in gene set testing

(2018) Xu Ren et al.   BIOINFORMATICS

DNA Hypomethylation in Blood Links B3GALT4 and ZADH2 to Alzheimer’s Disease

(2018) Andy Madrid et al.   JOURNAL OF ALZHEIMERS DISEASE

Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons

(2017) Michael C. Donohue et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Reactome Pathway Knowledgebase

(2017) Antonio Fabregat et al.   NUCLEIC ACIDS RESEARCH

A multivariate predictive modeling approach reveals a novel CSF peptide signature for both Alzheimer's Disease state classification and for predicting future disease progression

(2017) Daniel A. Llano et al.   PLoS One

Epigenome-Wide Association Study of Cognitive Functioning in Middle-Aged Monozygotic Twins

(2017) Anna Starnawska et al.   Frontiers in Aging Neuroscience

Epigenetic dysregulation in the developing Down syndrome cortex

(2016) Nady El Hajj et al.   Epigenetics

Role of GABAB receptors in learning and memory and neurological disorders

(2016) Chelcie F. Heaney et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

KEGG: new perspectives on genomes, pathways, diseases and drugs

(2016) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Development of Biomarkers Based on DNA Methylation in the NCAPH2/LMF2 Promoter Region for Diagnosis of Alzheimer’s Disease and Amnesic Mild Cognitive Impairment

(2016) Nobuyuki Kobayashi et al.   PLoS One

A Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits

(2016) Petr Volkov et al.   PLoS One

missMethyl: an R package for analyzing data from Illumina’s HumanMethylation450 platform

(2015) Belinda Phipson et al.   BIOINFORMATICS

Machine learning framework for early MRI-based Alzheimer's conversion prediction in MCI subjects

(2015) Elaheh Moradi et al.   NEUROIMAGE

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

RNA Sequence Analysis of Human Huntington Disease Brain Reveals an Extensive Increase in Inflammatory and Developmental Gene Expression

(2015) Adam Labadorf et al.   PLoS One

The Symbol Digit Modalities Test: Normative Data from a Large Nationally Representative Sample of Australians

(2014) Kim M. Kiely et al.   ARCHIVES OF CLINICAL NEUROPSYCHOLOGY

Promoter hypermethylation of the phosphatase DUSP22 mediates PKA-dependent TAU phosphorylation and CREB activation in Alzheimer's disease

(2014) Jose Vicente Sanchez-Mut et al.   HIPPOCAMPUS

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

(2014) Katie Lunnon et al.   NATURE NEUROSCIENCE

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

(2014) Philip L De Jager et al.   NATURE NEUROSCIENCE

Alzheimer’s disease drug-development pipeline: few candidates, frequent failures

(2014) Jeffrey L Cummings et al.   Alzheimers Research & Therapy

Deciphering the Molecular Profile of Plaques, Memory Decline and Neuron Loss in Two Mouse Models for Alzheimer’s Disease by Deep Sequencing

(2014) Yvonne Bouter et al.   Frontiers in Aging Neuroscience

The Preclinical Alzheimer Cognitive Composite

(2014) Michael C. Donohue et al.   JAMA Neurology

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

Improving Alzheimer’s disease phase II clinical trials

(2012) Barry D. Greenberg et al.   Alzheimers & Dementia

Rationale for use of the Clinical Dementia Rating Sum of Boxes as a primary outcome measure for Alzheimer’s disease clinical trials

(2012) Jesse M. Cedarbaum et al.   Alzheimers & Dementia

Comb-p: software for combining, analyzing, grouping and correcting spatially correlated P-values

(2012) B. S. Pedersen et al.   BIOINFORMATICS

Apolipoprotein B is a new target of the GDNF/RET and ET-3/EDNRB signalling pathways

(2012) C. Evangelisti et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

(2010) Pan Du et al.   BMC BIOINFORMATICS

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cerebrospinal Fluid Biomarkers and Rate of Cognitive Decline in Very Mild Dementia of the Alzheimer Type

(2009) Barbara J. Snider et al.   ARCHIVES OF NEUROLOGY

The FGF-2/FGFRs neurotrophic system promotes neurogenesis in the adult brain

(2009) G. Mudò et al.   JOURNAL OF NEURAL TRANSMISSION