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Title
RNA
modifications as emerging therapeutic targets
Authors
Keywords
-
Journal
Wiley Interdisciplinary Reviews-RNA
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2021-11-24
DOI
10.1002/wrna.1702
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- (2019) Hao Sheng et al. CARCINOGENESIS
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- (2019) Y. Grace Chen et al. MOLECULAR CELL
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- (2017) Modi Safra et al. NATURE
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- MODOMICS: a database of RNA modification pathways. 2017 update
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- Recent advances in dynamic m6A RNA modification
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- (2015) Claudio R. Alarcón et al. NATURE
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- (2015) Kazuko Nishikura NATURE REVIEWS MOLECULAR CELL BIOLOGY
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- (2015) Yasuhiro FURUICHI PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
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- (2015) Sara Haag et al. RNA
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- (2015) Wim F.P.M. Van den Hof et al. TOXICOLOGY IN VITRO
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- (2015) Jian Jiang et al. TOXICOLOGY LETTERS
- Profiling RNA editing in human tissues: towards the inosinome Atlas
- (2015) Ernesto Picardi et al. Scientific Reports
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- (2015) Gabrielle Bourgeois et al. PLoS One
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- (2015) Michael P Guy et al. RNA Biology
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- (2014) Nina V. Balmer et al. ARCHIVES OF TOXICOLOGY
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- (2014) Syuhei Nakao et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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- (2014) Ken-Wing Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2014) Xiaoqing Ren et al. MOLECULAR & CELLULAR PROTEOMICS
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- (2014) Joanna Rorbach et al. MOLECULAR BIOLOGY OF THE CELL
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- (2012) Jeffrey E. Squires et al. NUCLEIC ACIDS RESEARCH
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- (2012) T. Chujo et al. RNA
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- (2012) Clement T.Y. Chan et al. Nature Communications
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- (2011) M Tasaki et al. BRITISH JOURNAL OF CANCER
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- (2011) Baoman Li JOURNAL OF PSYCHIATRY & NEUROSCIENCE
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- (2011) M.G.L. Elferink et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
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- (2011) Jean-Matthieu Prot et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
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- (2011) Sandra Blanco et al. PLoS Genetics
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- (2010) Yuri Motorin et al. BIOCHEMISTRY
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- (2010) Bjorn-Erik Wulff et al. NATURE REVIEWS GENETICS
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