Derivation and Evaluation of Putative Adverse Outcome Pathways for the Effects of Cyclooxygenase Inhibitors on Reproductive Processes in Female Fish

A Neural Basis for Control of Cichlid Female Reproductive Behavior by Prostaglandin F 2α

(2016) Scott A. Juntti et al.   CURRENT BIOLOGY

The role of prostaglandins in the regulation of fish immunity

(2016) Victoria Gómez-Abellán et al.   MOLECULAR IMMUNOLOGY

Editor’s Highlight: Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS): A Web-Based Tool for Addressing the Challenges of Cross-Species Extrapolation of Chemical Toxicity

(2016) Carlie A. LaLone et al.   TOXICOLOGICAL SCIENCES

The role of eicosanoids in 17α, 20β-dihydroxy-4-pregnen-3-one-induced ovulation and spawning in Danio rerio

(2015) Olivia M. Knight et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Novel contraceptive targets to inhibit ovulation: the prostaglandin E2 pathway

(2015) Diane M. Duffy   HUMAN REPRODUCTION UPDATE

Increasing Scientific Confidence in Adverse Outcome Pathways: Application of Tailored Bradford-Hill Considerations for Evaluating Weight of Evidence

(2015) Richard A. Becker et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Temporal Changes in Biological Responses and Uncertainty in Assessing Risks of Endocrine-Disrupting Chemicals: Insights from Intensive Time-Course Studies with Fish

(2015) Gerald T. Ankley et al.   TOXICOLOGICAL SCIENCES

Therapeutic implications of the prostaglandin pathway in Alzheimer's disease

(2014) Eiron Cudaback et al.   BIOCHEMICAL PHARMACOLOGY

Roles of prostaglandin receptors in female reproduction

(2014) Y. Sugimoto et al.   JOURNAL OF BIOCHEMISTRY

The Comparative Toxicogenomics Database's 10th year anniversary: update 2015

(2014) Allan Peter Davis et al.   NUCLEIC ACIDS RESEARCH

COX-2 inhibitors arrest prostate cancer cell cycle progression by down-regulation of kinetochore/centromere proteins

(2014) Jared Bieniek et al.   PROSTATE

Adverse Outcome Pathway (AOP) Development I: Strategies and Principles

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Adverse Outcome Pathway Development II: Best Practices

(2014) Daniel L. Villeneuve et al.   TOXICOLOGICAL SCIENCES

Role of arachidonic acid cascade in Rhinella arenarum oocyte maturation

(2014) Maria Eugenia Ortiz et al.   ZYGOTE

Prostaglandin receptor EP3 mediates growth inhibitory effect of aspirin through androgen receptor and contributes to castration resistance in prostate cancer cells

(2013) Eiji Kashiwagi et al.   ENDOCRINE-RELATED CANCER

The Read-Across Hypothesis and Environmental Risk Assessment of Pharmaceuticals

(2013) Mariann Rand-Weaver et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Rapid modulation of gene expression profiles in the telencephalon of male goldfish following exposure to waterborne sex pheromones

(2013) Wudu E. Lado et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Functional interactions between vasotocin and prostaglandins during final oocyte maturation and ovulation in the catfish Heteropneustes fossilis

(2013) K.P. Joy et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Recent Advances in the Understanding of Teleost Medaka Ovulation: The Roles of Proteases and Prostaglandins

(2013) Takayuki Takahashi et al.   ZOOLOGICAL SCIENCE

Push-through direct injection NMR: an optimized automation method applied to metabolomics

(2012) Quincy Teng et al.   ANALYST

Update on EPA’s ToxCast Program: Providing High Throughput Decision Support Tools for Chemical Risk Management

(2012) Robert Kavlock et al.   CHEMICAL RESEARCH IN TOXICOLOGY

TOX 21: New Dimensions of Toxicity Testing

(2012) Charles W. Schmidt   ENVIRONMENTAL HEALTH PERSPECTIVES

Metabolite Profiling and a Transcriptional Activation Assay Provide Direct Evidence of Androgen Receptor Antagonism by Bisphenol A in Fish

(2012) D. R. Ekman et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Characterization of multiple membrane progestin receptor (mPR) subtypes from the goldfish ovary and their roles in the induction of oocyte maturation

(2012) Toshinobu Tokumoto et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Aggregating Data for Computational Toxicology Applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System

(2012) Richard S. Judson et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Effects of the antihistamine diphenhydramine on selected aquatic organisms

(2011) Jason P. Berninger et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Spindle assembly checkpoint and its regulators in meiosis

(2011) Shao-Chen Sun et al.   HUMAN REPRODUCTION UPDATE

A graphical systems model and tissue-specific functional gene sets to aid transcriptomic analysis of chemical impacts on the female teleost reproductive axis

(2011) Daniel L. Villeneuve et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

In Vivo Induction of Oocyte Maturation and Ovulation in Zebrafish

(2011) Toshinobu Tokumoto et al.   PLoS One

Prostaglandin E2 release from astrocytes triggers gonadotropin-releasing hormone (GnRH) neuron firing via EP2 receptor activation

(2011) J. Clasadonte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmaceuticals in the aquatic environment: A critical review of the evidence for health effects in fish

(2010) Jenna Corcoran et al.   CRITICAL REVIEWS IN TOXICOLOGY

Elucidation of Mechanisms of the Reciprocal Cross Talk between Gonadotropin-Releasing Hormone and Prostaglandin Receptors

(2010) Michal Naidich et al.   ENDOCRINOLOGY

Impacts of an Anti-Androgen and an Androgen/Anti-Androgen Mixture on the Metabolite Profile of Male Fathead Minnow Urine

(2010) Timothy W. Collette et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Use of gene expression, biochemical and metabolite profiles to enhance exposure and effects assessment of the model androgen 17β-trenbolone in fish

(2010) Drew R. Ekman et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Expression of cyclooxygenase-2 and prostaglandin receptor EP4b mRNA in the ovary of the medaka fish, Oryzias latipes: Possible involvement in ovulation

(2010) Chika Fujimori et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Oral administration of the cyclooxygenase-2 (COX-2) inhibitor meloxicam blocks ovulation in non-human primates when administered to simulate emergency contraception

(2009) K. E. Hester et al.   HUMAN REPRODUCTION

Leveraging mammalian pharmaceutical toxicology and pharmacology data to predict chronic fish responses to pharmaceuticals

(2009) Jason P. Berninger et al.   TOXICOLOGY LETTERS

NSAIDs revisited: Putative molecular basis of their interactions with peroxisome proliferator-activated gamma receptor (PPARγ)

(2008) Nelilma C. Romeiro et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

An investigation into the role of prostaglandins in zebrafish oocyte maturation and ovulation

(2008) A.L. Lister et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Gene Duplications and Losses within the Cyclooxygenase Family of Teleosts and Other Chordates

(2008) J. C. Havird et al.   MOLECULAR BIOLOGY AND EVOLUTION