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Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide

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Radiomic subtyping improves disease stratification beyond key molecular, clinical, and standard imaging characteristics in patients with glioblastoma

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The Epitranscriptome of Noncoding RNAs in Cancer

(2017) Manel Esteller et al.   Cancer Discovery

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A Landscape of Pharmacogenomic Interactions in Cancer

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Posttranscriptional methylation of transfer and ribosomal RNA in stress response pathways, cell differentiation, and cancer

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Pharmacokinetics and derivation of an anticancer dosing regimen for the novel anti-cancer agent isobutyl-deoxynyboquinone (IB-DNQ), a NQO1 bioactivatable molecule, in the domestic felid species

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Advances in the molecular genetics of gliomas — implications for classification and therapy

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Translating the Genome in Time and Space: Specialized Ribosomes, RNA Regulons, and RNA-Binding Proteins

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Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders

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A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

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Modulation of oxidative stress as an anticancer strategy

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Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively

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An NQO1 Substrate with Potent Antitumor Activity That Selectively Kills by PARP1-Induced Programmed Necrosis

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(2012) Christine Vogel et al.   NATURE REVIEWS GENETICS

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rRNA Pseudouridylation Defects Affect Ribosomal Ligand Binding and Translational Fidelity from Yeast to Human Cells

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Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways

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NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

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Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma

(2010) Houtan Noushmehr et al.   CANCER CELL

Loss of Function of the Tumor Suppressor DKC1 Perturbs p27 Translation Control and Contributes to Pituitary Tumorigenesis

(2010) C. Bellodi et al.   CANCER RESEARCH

Deregulation of oncogene-induced senescence and p53 translational control in X-linked dyskeratosis congenita

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Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism

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Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiency

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Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE