Structural and compositional diversity in the kainate receptor family

Differences in interactions between transmembrane domains tune the activation of metabotropic glutamate receptors

(2021) Jordana K Thibado et al.   eLife

FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices

(2021) Eitan Lerner et al.   eLife

Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor

(2021) Nandish Khanra et al.   eLife

Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data

(2021) Robin Herbrechter et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Defining the Homo- and Heterodimerization Propensities of Metabotropic Glutamate Receptors

(2020) Joon Lee et al.   Cell Reports

Subunit-selective iGluR antagonists can potentiate heteromeric receptor responses by blocking desensitization

(2020) Stefan Pollok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM

(2019) Yan Zhao et al.   SCIENCE

Complementary networks of cortical somatostatin interneurons enforce layer specific control

(2019) Alexander Naka et al.   eLife

The structural arrangement and dynamics of the heteromeric GluK2/GluK5 kainate receptor as determined by smFRET

(2019) Douglas B. Litwin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Structural and Functional Insights into GluK3-kainate Receptor Desensitization and Recovery

(2019) Jyoti Kumari et al.   Scientific Reports

Conformational dynamics between transmembrane domains and allosteric modulation of a metabotropic glutamate receptor

(2019) Vanessa A Gutzeit et al.   eLife

Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix

(2019) Dorothee Liebschner et al.   Acta Crystallographica Section D-Structural Biology

ALK4 coordinates extracellular and intrinsic signals to regulate development of cortical somatostatin interneurons

(2019) Christina Göngrich et al.   JOURNAL OF CELL BIOLOGY

Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo

(2019) Amanda Acosta-Ruiz et al.   NEURON

Glutamatergic Signaling in the Central Nervous System: Ionotropic and Metabotropic Receptors in Concert

(2018) Andreas Reiner et al.   NEURON

Shared and distinct transcriptomic cell types across neocortical areas

(2018) Bosiljka Tasic et al.   NATURE

Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK

(2018) Perrine Royal et al.   NEURON

Signal peptide represses GluK1 surface and synaptic trafficking through binding to amino-terminal domain

(2018) Gui-Fang Duan et al.   Nature Communications

New tools for automated high-resolution cryo-EM structure determination in RELION-3

(2018) Jasenko Zivanov et al.   eLife

N -glycan content modulates kainate receptor functional properties

(2017) Claire G. Vernon et al.   JOURNAL OF PHYSIOLOGY-LONDON

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

UCSF ChimeraX: Meeting modern challenges in visualization and analysis

(2017) Thomas D. Goddard et al.   PROTEIN SCIENCE

Layer-specific modulation of neocortical dendritic inhibition during active wakefulness

(2017) William Muñoz et al.   SCIENCE

Neto Auxiliary Subunits Regulate Interneuron Somatodendritic and Presynaptic Kainate Receptors to Control Network Inhibition

(2017) Megan S. Wyeth et al.   Cell Reports

Chrna2-Martinotti Cells Synchronize Layer 5 Type A Pyramidal Cells via Rebound Excitation

(2017) Markus M. Hilscher et al.   PLOS BIOLOGY

Preferential assembly of heteromeric kainate and AMPA receptor amino terminal domains

(2017) Huaying Zhao et al.   eLife

Ionotropic glutamate receptors: Which ones, when, and where in the mammalian neocortex

(2016) Minela Hadzic et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Structural basis of kainate subtype glutamate receptor desensitization

(2016) Joel R. Meyerson et al.   NATURE

Single-molecule imaging of non-equilibrium molecular ensembles on the millisecond timescale

(2016) Manuel F Juette et al.   NATURE METHODS

Disentangling neural cell diversity using single-cell transcriptomics

(2016) Jean-Francois Poulin et al.   NATURE NEUROSCIENCE

Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins

(2016) Keiko Matsuda et al.   NEURON

Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels

(2016) Joshua Levitz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Manipulation of Subunit Stoichiometry in Heteromeric Membrane Proteins

(2016) Claudio L. Morales-Perez et al.   STRUCTURE

Distinct Subunit Domains Govern Synaptic Stability and Specificity of the Kainate Receptor

(2016) Christoph Straub et al.   Cell Reports

CTFFIND4: Fast and accurate defocus estimation from electron micrographs

(2015) Alexis Rohou et al.   JOURNAL OF STRUCTURAL BIOLOGY

Structural mechanism of glutamate receptor activation and desensitization

(2014) Joel R. Meyerson et al.   NATURE

Screening and large-scale expression of membrane proteins in mammalian cells for structural studies

(2014) April Goehring et al.   Nature Protocols

Parkin regulates kainate receptors by interacting with the GluK2 subunit

(2014) AnnaMaria Maraschi et al.   Nature Communications

Self-assembled monolayers improve protein distribution on holey carbon cryo-EM supports

(2014) Joel R. Meyerson et al.   Scientific Reports

NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

(2013) Pierre Paoletti et al.   NATURE REVIEWS NEUROSCIENCE

Kainate Receptors in Health and Disease

(2013) Juan Lerma et al.   NEURON

Neto1 and Neto2: auxiliary subunits that determine key properties of native kainate receptors

(2012) Susumu Tomita et al.   JOURNAL OF PHYSIOLOGY-LONDON

Dancing partners at the synapse: auxiliary subunits that shape kainate receptor function

(2012) Bryan A. Copits et al.   NATURE REVIEWS NEUROSCIENCE

Zinc Potentiates GluK3 Glutamate Receptor Function by Stabilizing the Ligand Binding Domain Dimer Interface

(2012) Julien Veran et al.   NEURON

Assembly Stoichiometry of the GluK2/GluK5 Kainate Receptor Complex

(2012) Andreas Reiner et al.   Cell Reports

Probing cellular protein complexes using single-molecule pull-down

(2011) Ankur Jain et al.   NATURE

Structure and Assembly Mechanism for Heteromeric Kainate Receptors

(2011) Janesh Kumar et al.   NEURON

Kainate receptors coming of age: milestones of two decades of research

(2011) Anis Contractor et al.   TRENDS IN NEUROSCIENCES

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal Structures of the Glutamate Receptor Ion Channel GluK3 and GluK5 Amino-Terminal Domains

(2010) Janesh Kumar et al.   JOURNAL OF MOLECULAR BIOLOGY

A practical guide to single-molecule FRET

(2008) Rahul Roy et al.   NATURE METHODS