A pan-cancer analysis revealing the role of TIGIT in tumor microenvironment
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Title
A pan-cancer analysis revealing the role of TIGIT in tumor microenvironment
Authors
Keywords
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Journal
Scientific Reports
Volume 11, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-11-18
DOI
10.1038/s41598-021-01933-9
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Note: Only part of the references are listed.- TIGIT promotes CD8+T cells exhaustion and predicts poor prognosis of colorectal cancer
- (2021) Rongpu Liang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Additive Role of Immune System Infiltration and Angiogenesis in Uveal Melanoma Progression
- (2021) Sandra García-Mulero et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Intratumoral CXCL13+CD8+T cell infiltration determines poor clinical outcomes and immunoevasive contexture in patients with clear cell renal cell carcinoma
- (2021) Siyuan Dai et al. Journal for ImmunoTherapy of Cancer
- COM902, a novel therapeutic antibody targeting TIGIT augments anti-tumor T cell function in combination with PVRIG or PD-1 pathway blockade
- (2021) Kyle Hansen et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Analysis of the PD-1 Ligands Among Gastrointestinal Cancer Patients: Focus on Cancer Immunity
- (2021) Lin Dai et al. Frontiers in Oncology
- Microsatellite instability: a review of what the oncologist should know
- (2020) Kai Li et al. Cancer Cell International
- Combined evaluation of the expression status of CD155 and TIGIT plays an important role in the prognosis of LUAD (lung adenocarcinoma)
- (2020) Yu Sun et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- A Novel D Peptide Identified by Mirror‐image Phage Display Blocks TIGIT/PVR for Cancer Immunotherapy
- (2020) Xiuman Zhou et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Immune checkpoint signaling and cancer immunotherapy
- (2020) Xing He et al. CELL RESEARCH
- Visualizing and interpreting cancer genomics data via the Xena platform
- (2020) Mary J. Goldman et al. NATURE BIOTECHNOLOGY
- A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling
- (2020) Junbin Qian et al. CELL RESEARCH
- IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma
- (2020) Joe-Marc Chauvin et al. CLINICAL CANCER RESEARCH
- Role of Epigenetic Modifications in Inhibitory Immune Checkpoints in Cancer Development and Progression
- (2020) Reem Saleh et al. Frontiers in Immunology
- A 1p/19q Codeletion-Associated Immune Signature for Predicting Lower Grade Glioma Prognosis
- (2020) Jie Xu et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Intratumoral TIGIT+ CD8+ T-cell infiltration determines poor prognosis and immune evasion in patients with muscle-invasive bladder cancer
- (2020) Zhaopei Liu et al. Journal for ImmunoTherapy of Cancer
- TIGIT in cancer immunotherapy
- (2020) Joe-Marc Chauvin et al. Journal for ImmunoTherapy of Cancer
- A novel human anti-TIGIT monoclonal antibody with excellent function in eliciting NK cell-mediated antitumor immunity
- (2020) Dong Han et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Overall survival according to immunotherapy and radiation treatment for metastatic non-small-cell lung cancer: a National Cancer Database analysis
- (2019) Corey C. Foster et al. Radiation Oncology
- Tumor mutational burden is predictive of response to immune checkpoint inhibitors in MSI-high metastatic colorectal cancer
- (2019) A B Schrock et al. ANNALS OF ONCOLOGY
- Determining cell type abundance and expression from bulk tissues with digital cytometry
- (2019) Aaron M. Newman et al. NATURE BIOTECHNOLOGY
- GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis
- (2019) Zefang Tang et al. NUCLEIC ACIDS RESEARCH
- Clinical and molecular predictors of response to immune checkpoint inhibitors in patients with advanced esophagogastric cancer
- (2019) Megan Greally et al. CLINICAL CANCER RESEARCH
- Optimized fractionated radiotherapy with anti-PD-L1 and anti-TIGIT: a promising new combination
- (2019) Mathieu Grapin et al. Journal for ImmunoTherapy of Cancer
- Cytolytic activity correlates with the mutational burden and deregulated expression of immune checkpoints in colorectal cancer
- (2019) Apostolos Zaravinos et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Toward understanding the origin and evolution of cellular organisms
- (2019) Minoru Kanehisa PROTEIN SCIENCE
- A TIGIT-based chimeric co-stimulatory switch receptor improves T-cell anti-tumor function
- (2019) Shiran Hoogi et al. Journal for ImmunoTherapy of Cancer
- PD-1+ TIGIT+ CD8+ T cells are associated with pathogenesis and progression of patients with hepatitis B virus-related hepatocellular carcinoma
- (2019) Xiaoli Liu et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load
- (2019) Hyunchul Jung et al. Nature Communications
- Single-cell transcriptome analysis reveals tumor immune microenvironment heterogenicity and granulocytes enrichment in colorectal cancer liver metastases
- (2019) Yunbin Zhang et al. CANCER LETTERS
- DNA Methyltransferase Inhibitors: Catalysts For Antitumour Immune Responses
- (2019) Huimin Dan et al. OncoTargets and Therapy
- Reduced GRAMD1C expression correlates to poor prognosis and immune infiltrates in kidney renal clear cell carcinoma
- (2019) Haiyan Hao et al. PeerJ
- Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity
- (2018) Qing Zhang et al. NATURE IMMUNOLOGY
- TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM
- (2018) Alice L. Hung et al. OncoImmunology
- Association of Immunotherapy With Durable Survival as Defined by Value Frameworks for Cancer Care
- (2018) Omer Ben-Aharon et al. JAMA Oncology
- TIGIT: a novel immunotherapy target moving from bench to bedside
- (2018) Benjamin L. Solomon et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- DNA methylation and repressive histones in the promoters of PD-1, CTLA-4, TIM-3, LAG-3, TIGIT, PD-L1, and galectin-9 genes in human colorectal cancer
- (2018) Varun Sasidharan Nair et al. Clinical Epigenetics
- Universal screening for microsatellite instability in colorectal cancer in the clinical genomics era: new recommendations, methods, and considerations
- (2017) Jaclyn F. Hechtman et al. Familial Cancer
- Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
- (2017) Zachary R. Chalmers et al. Genome Medicine
- Gene expression markers of Tumor Infiltrating Leukocytes
- (2017) Patrick Danaher et al. Journal for ImmunoTherapy of Cancer
- Genome-wide association analysis identifies genetic correlates of immune infiltrates in solid tumors
- (2017) Nathan O. Siemers et al. PLoS One
- Adaptive NK Cells with Low TIGIT Expression Are Inherently Resistant to Myeloid-Derived Suppressor Cells
- (2016) Dhifaf Sarhan et al. CANCER RESEARCH
- Reversing T-cell Dysfunction and Exhaustion in Cancer
- (2016) H. M. Zarour CLINICAL CANCER RESEARCH
- Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability
- (2016) Bernhard Mlecnik et al. IMMUNITY
- Binding of the Fap2 Protein of Fusobacterium nucleatum to Human Inhibitory Receptor TIGIT Protects Tumors from Immune Cell Attack
- (2015) Chamutal Gur et al. IMMUNITY
- TIGIT and PD-1 impair tumor antigen–specific CD8+ T cells in melanoma patients
- (2015) Joe-Marc Chauvin et al. JOURNAL OF CLINICAL INVESTIGATION
- Divergent Phenotypes of Human Regulatory T Cells Expressing the Receptors TIGIT and CD226
- (2015) Christopher A. Fuhrman et al. JOURNAL OF IMMUNOLOGY
- Toward understanding and exploiting tumor heterogeneity
- (2015) Ash A Alizadeh et al. NATURE MEDICINE
- Inducible but Not Constitutive Expression of PD-L1 in Human Melanoma Cells Is Dependent on Activation of NF-κB
- (2015) Kavitha Gowrishankar et al. PLoS One
- The Immunoreceptor TIGIT Regulates Antitumor and Antiviral CD8 + T Cell Effector Function
- (2014) Robert J. Johnston et al. CANCER CELL
- Treg Cells Expressing the Coinhibitory Molecule TIGIT Selectively Inhibit Proinflammatory Th1 and Th17 Cell Responses
- (2014) Nicole Joller et al. IMMUNITY
- Molecular Dissection of Microsatellite Instable Colorectal Cancer
- (2013) Eduardo Vilar et al. Cancer Discovery
- Global DNA hypomethylation in cancer: review of validated methods and clinical significance
- (2012) Estela G. Toraño et al. CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Immune Inhibitory Molecules LAG-3 and PD-1 Synergistically Regulate T-cell Function to Promote Tumoral Immune Escape
- (2011) S.-R. Woo et al. CANCER RESEARCH
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
- Dissecting DNA hypermethylation in cancer
- (2010) Marcos R.H. Estécio et al. FEBS LETTERS
- Microsatellite instability in colorectal cancer—the stable evidence
- (2010) Eduardo Vilar et al. Nature Reviews Clinical Oncology
- A novel molecular interaction for the adhesion of follicular CD4 T cells to follicular DC
- (2009) Kent S. Boles et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity
- (2009) N. Stanietsky et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells
- (2008) Xin Yu et al. NATURE IMMUNOLOGY
- Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection
- (2008) Shawn D Blackburn et al. NATURE IMMUNOLOGY
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